R-PLEX Human GITRL Antibody Set

R-PLEX Human GITRL Antibody Set Overview
The R-PLEX Human GITRL Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of GITRL in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX and U-PLEX analytes, can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products click here.

R-PLEX Human GITRL Antibody Set Features
  • Measures human GITRL in serum, plasma, and cell lysate
  • Dynamic range: 1.4-50,000 pg/mL
  • Median LLOD: 1.4 pg/mL
  • Can be used to develop individual analyte assays as well as multiplex panels

Typical Data
Calibration curve for the R-PLEX Human GITRL Antibody Set was assessed and representative data is presented below.

Figure 1. R-PLEX Human GITRL Antibody Set Calibration Curve
Calibration Curve for R-PLEX Human GITRL Antibody Set
GITRL Analyte

Description - Ligand for Glucocorticoid-Induced TNFR-related protein (GITRL, AITRL, TNFSF18, TNLG2A) is a cytokine in the TNF ligand family that binds to the GITR/AITR receptor. GITRL acts as a costimulator to lower the threshold for T-cell activation and proliferation. GITRL is important for interactions between activated T lymphocytes and endothelial cells. It promotes leukocyte adhesion to endothelial cells and is chemoattractant, drawing monocytes to sites of inflammation.

Disease Research Area - Autoimmune & Inflammation

Application Area - Immunology/Inflammation, Immuno-Oncology

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5 plate size
50 plate size
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