R-PLEX Human FGF (basic) Antibody Set

R-PLEX Human FGF (basic) Overview
The R-PLEX Human FGF (basic) includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of FGF (basic) in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX plus U-PLEX analytes can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products click here.

R-PLEX Human FGF (basic) Features
  • Measures human FGF (basic) in serum, plasma, and urine
  • Dynamic range: 1.1 - 2,000 pg/mL
  • Median LLOD: 1.1 pg/mL
  • Can be used to develop individual analyte assays as well as multiplex panels

Typical Data
Calibration curve for the R-PLEX Human FGF (basic) was assessed and representative data is presented below.

Figure 1. R-PLEX Human FGF (basic) Calibration Curve
Calibration curve for R-PLEX Human FGF
FGF (basic) Analyte

Description - Basic Fibroblast Growth Factor (FGF (basic), bFGF, FGFB, FGF-2, HBGF-2, FGF2) is a member of the FGF family of growth factors. It stimulates the growth and development of new blood vessels (angiogenesis) that contribute to the pathogenesis of several diseases (e.g. cancer, atherosclerosis). The mammalian FGFs mediate numerous developmental programs during embryogenesis and play critical roles in adult tissue repair and maintenance. bFGF has a heparin binding domain and oligimerizes upon binding to heparin making it less available to detection. Heparin plasma samples should not be tested for bFGF.

Disease Research Area - Angiogenesis, Cancer, Atherosclerosis

Application Area - Angiogenesis & Vascular, Oncology & Cancer

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5 plate size
50 plate size
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