R-PLEX Human FGF-23 Antibody Set

Please note: This analyte is also sold as a U-PLEX assay. Click here to be directed to the U-PLEX assay page. MSD is continuing to sell this R-PLEX Antibody Set until inventory is depleted. If you want to order the R-PLEX Antibody Set, you can choose to purchase it from this page.

R-PLEX Human FGF-23 Antibody Set Overview
The R-PLEX Human FGF-23 Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of FGF-23 in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX and U-PLEX analytes, can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products click here.

R-PLEX Human FGF-23 Antibody Set Features
  • Measures human FGF-23 in serum and plasma
  • Dynamic range: 1.5-10,000 pg/mL
  • Median LLOD: 1.5 pg/mL
  • Can be used to develop individual analyte assays as well as multiplex panels

Typical Data
Calibration curve for the R-PLEX Human FGF-23 Antibody Set was assessed and representative data is presented below.

Figure 1. R-PLEX Human FGF-23 Antibody Set Calibration Curve
Calibration Curve for R-PLEX Human FGF-23 Antibody Set
FGF-23 Analyte

Description - Fibroblast Growth Factor 23 (FGF-23, ADHR, FGFN, HPDR2, HYPF, phosphatonin) is secreted primarily by osteocytes/osteoblasts in bone. High serum phosphate levels stimulate FGF-23 expression and secretion. Excess FGF-23 production results in hypophosphatemia, suppressed 1,25(OH)2 vitamin D levels, elevated PTH levels, and impaired bone and cartilage mineralization. Its deficiency results in hyperphosphatemia, elevated 1,25(OH)2 vitamin D levels, suppressed PTH and soft tissue calcification.

Disease Research Area - Metabolic Diseases

Application Area - Metabolic, Oncology & Cancer

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