R-PLEX Human Clusterin Antibody Set

R-PLEX Human Clusterin Antibody Set Overview
The R-PLEX Human Clusterin Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of Clusterin in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX plus U-PLEX analytes can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products click here.

R-PLEX Human Clusterin Antibody Set Features
  • Measures human Clusterin in plasma
  • Dynamic range: 153 - 1,000,000 pg/mL
  • Median LLOD: 153 pg/mL
  • Can be used to develop individual analyte assays as well as multiplex panels

Typical Data
Calibration curve for the R-PLEX Human Clusterin Antibody Set was assessed and representative data is presented below.

Figure 1. R-PLEX Human Clusterin Antibody Set Calibration Curve
Calibration curve for R-PLEX Human Clusterin Antibody Set
Clusterin Analyte

Description - Clusterin (CLI, AAG4, APOJ, CLU1, CLU2, KUB1, SGP2, APO-J, SGP-2, SP-40, TRPM2, TRPM-2, NA1/NA2, CLU) is a glycoprotein that is found in most mammalian tissues. The localized over-expression of clusterin at sites of tissue damage or stress indicates that clusterin acts as a molecular chaperone displaying cytoprotective characteristics. Increased expression has been consistently detected in damaged tissues from brain, liver, breast, and kidney. In the kidney, marked induction of clusterin occurs following renal tubule injury. Clusterin levels in urine can be used to distinguish between glomerular and tubular injuries; they can also be used to assess the severity and progression of renal damage.

Disease Research Area - Tissue Damage, Stress

Application Area - Intracellular Signaling, Apoptosis

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5 plate size
50 plate size
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