R-PLEX Human CD27 Antibody Set

R-PLEX Human CD27 Antibody Set Overview
The R-PLEX Human CD27 Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of CD27 in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX and U-PLEX analytes, can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products click here.

R-PLEX Human CD27 Antibody Set Features
  • Measures human CD27 in plasma
  • Dynamic range: 1.7-50,000 pg/mL
  • Median LLOD: 1.7 pg/mL
  • Can be used to develop individual analyte assays as well as multiplex panels

Typical Data
Calibration curve for the R-PLEX Human CD27 Antibody Set was assessed and representative data is presented below.

Figure 1. R-PLEX Human CD27 Antibody Set Calibration Curve
Calibration Curve for R-PLEX Human CD27 Antibody Set
CD27 Analyte

Description - CD27 (CD27L receptor, S152, T14, TNFRSF7) is a TNFR superfamily co-stimulatory immune checkpoint molecule. When bound by CD70 it positively regulates T-cell expansion, effector function, and the differentiation of memory T cells. The CD27/70 axis also regulates B-cell activation and antibody synthesis. CD27 induces apoptosis through SIVA. Soluble CD27 (sCD27) is elevated in individuals with cancer after immunotherapy.

Disease Research Area - Oncology

Application Area - Oncology & Cancer, , Immuno-Oncology

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5 plate size
50 plate size
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