R-PLEX Human BAFF-R Antibody Set

R-PLEX Human BAFF-R Antibody Set Overview
The R-PLEX Human BAFF-R Antibody Set includes a matched capture and detection antibody pair and calibrator for the quick and easy measurement of BAFF-R in biological samples. R-PLEX products leverage MSD’s electrochemiluminescence technology for better sensitivity and a larger dynamic range than traditional ELISAs. R-PLEX matched antibody sets enable the development of singleplex and multiplex immunoassays. Individual assays may be developed using MSD avidin- or streptavidin-coated plates. Custom multiplex assays with any combination of R-PLEX analytes, as well as R-PLEX plus U-PLEX analytes can be developed on U-PLEX MULTI-SPOT plates. To learn more about the advantages of R-PLEX products click here.

R-PLEX Human BAFF-R Antibody Set Features
  • Measures human BAFF-R in serum, plasma, and urine
  • Dynamic range: 2.4 - 100,000 pg/mL
  • Median LLOD: 2.4 pg/mL
  • Can be used to develop individual analyte assays as well as multiplex panels

Typical Data
Calibration curve for the R-PLEX Human BAFF-R Antibody Set was assessed and representative data is presented below.

Figure 1. R-PLEX Human BAFF-R Antibody Set Calibration Curve
Calibration curve for R-PLEX Human BAFF-R Antibody Set
BAFF-R Analyte

Description - B-Cell Activating Factor Receptor (BAFFR, CD268, CVID4, BAFF-R, BROMIX, TNFRSF13C) is one of three known receptors for BAFF, which regulates B- and T-cell function. BAFF-R is required for B-cell maturation and is predominantly expressed on peripheral B-cells. BAFF-R has also been associated with costimulation of T-cells. BAFF/BAFF-R signaling has been widely implicated to play a role in autoimmune conditions in both humans and mice. BAFF levels are significantly elevated in patients with systemic lupus erythematosus, systemic sclerosis, and rheumatoid arthritis.

Disease Research Area - Systemic Lupus Erythematosus, Systemic Sclerosis, Rheumatoid Arthritis

Application Area - Inflammation, Immunology

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5 plate size
50 plate size
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