Galectin-9, a Player in Cytokine Release Syndrome and a Surrogate Diagnostic Biomarker in SARS-CoV-2 Infection

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Galectin-9, a Player in Cytokine Release Syndrome and a Surrogate Diagnostic Biomarker in SARS-CoV-2 Infection

Najmeh Bozorgmehr, Siavash Mashhouri, Eliana Perez Rosero, Lai Xu, Shima Shahbaz, Wendy Sligl, Mohammed Osman, Demetrios J. Kutsogiannis, Erika MacIntyre, Conar R. O’Neil, Shokrollah Elahi

Journal		mBio
Species
Analytes Measured		Eotaxin , Eotaxin-3 , Galectin-9 , GM-CSF , IFN-gamma , IL-1a , IL-1beta , IL-2 , IL-4 , IL-5 , IL-6 , IL-7 , IL-8 , IL-8 - HA , IL-10 , IL-12 IL-23p40 , IL-12 p70 , IL-13 , IL-15 , IL-16 , IL-17A , IP-10 , MCP-1 , MCP-4 , MDC , MIP-1alpha , MIP-1beta , TARC , TNF-alpha , TNF-beta , VEGF-A
Matrix Tested

Year		2021
Volume		Journal Volume
Page Numbers		Journal Page Number(s)
Application

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V-PLEX Plus Human Cytokine 29-Plex Kit Eotaxin, Eotaxin-3, GM-CSF, IFN-γ, IL-1α, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-7, IL-8, IL-10, IL-12/IL-23p40, IL-12p70, IL-13, IL-15, IL-16, IL-17A, IP-10, MCP-1, MCP-4, MDC, MIP-1α, MIP-1β, TARC, TNF-α, TNF-β, VEGF-A \| Human Multiplex
V-PLEX Custom Human Biomarkers 1 C-Peptide, Eotaxin, Eotaxin-3, GIP (active), GLP-1 (active), Glucagon, GM-CSF, IFN-γ, IL-1α, IL-1β, IL-1RA, IL-2, IL-3, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, IL-10, IL-12/IL-23p40, IL-12p70, IL-13, IL-15, IL-16, IL-17A, IL-17A/F, IL-17B, IL-17C, IL-17D, Insulin, IP-10, Leptin, MCP-1, MCP-4, MDC, MIP-1α, MIP-1β, PP, TARC, TNF-α, TNF-β, TSLP, VEGF-A \| Human Multiplex		NEW
V-PLEX Custom NHP Biomarkers 1 C-Peptide, Eotaxin, Eotaxin-3, GIP (active), GLP-1 (active), Glucagon, GM-CSF, IFN-γ, IL-1β, IL-2, IL-5, IL-6, IL-7, IL-8, IL-10, IL-12/IL-23p40, IL-15, IL-16, IL-17A, Insulin, IP-10, MCP-1, MCP-4, MDC, MIP-1α, MIP-1β, PP, TARC, TNF-β, VEGF-A \| Non-human primate Multiplex		NEW
V-PLEX Custom Mouse Biomarkers IFN-γ, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-9, IL-10, IL-12p70, IL-15, IL-17A/F, IL-27p28/IL-30, IL-33, IP-10, KC/GRO, MCP-1, MIP-1α, MIP-2, TNF-α \| Mouse Multiplex		NEW
V-PLEX Plus Mouse TNF-α Kit TNF-α \| Mouse Singleplex		NEW
V-PLEX Plus Mouse IL-6 Kit IL-6 \| Mouse Singleplex		NEW
V-PLEX Plus Mouse IL-1β Kit IL-1β \| Mouse Singleplex		NEW
V-PLEX Plus Mouse IFN-γ Kit IFN-γ \| Mouse Singleplex		NEW
V-PLEX Mouse TNF-α Kit TNF-α \| Mouse Singleplex		NEW
V-PLEX Mouse IL-6 Kit IL-6 \| Mouse Singleplex		NEW
V-PLEX Mouse IL-1β Kit IL-1β \| Mouse Singleplex		NEW
V-PLEX Mouse IFN-γ Kit IFN-γ \| Mouse Singleplex		NEW
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V-PLEX Mouse IL-2 Kit IL-2 \| Mouse Singleplex		NEW
V-PLEX Proinflammatory Panel 1 Mouse Kit IFN-γ, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-10, IL-12p70, KC/GRO, TNF-α \| Mouse Multiplex		NEW
V-PLEX Plus Proinflammatory Panel 1 Mouse Kit IFN-γ, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-10, IL-12p70, KC/GRO, TNF-α \| Mouse Multiplex		NEW
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V-PLEX Plus Mouse IL-10 Kit IL-10 \| Mouse Singleplex		NEW
V-PLEX Plus Mouse IL-5 Kit IL-5 \| Mouse Singleplex		NEW
V-PLEX Plus Mouse IL-4 Kit IL-4 \| Mouse Singleplex		NEW
V-PLEX Mouse IL-12p70 Kit IL-12p70 \| Mouse Singleplex		NEW
V-PLEX Mouse IL-10 Kit IL-10 \| Mouse Singleplex		NEW
V-PLEX Mouse IL-5 Kit IL-5 \| Mouse Singleplex		NEW
V-PLEX Mouse IL-4 Kit IL-4 \| Mouse Singleplex		NEW
V-PLEX Plus NHP MIP-1β Gen. B Kit MIP-1β \| Non-human primate Singleplex
V-PLEX NHP MIP-1β Gen. B Kit MIP-1β \| Non-human primate Singleplex
V-PLEX Plus NHP MCP-1 Gen. B Kit MCP-1 \| Non-human primate Singleplex
V-PLEX NHP MCP-1 Gen. B Kit MCP-1 \| Non-human primate Singleplex
V-PLEX Plus NHP MIP-1α Gen. B Kit MIP-1α \| Non-human primate Singleplex
V-PLEX NHP MIP-1α Gen. B Kit MIP-1α \| Non-human primate Singleplex
V-PLEX Plus NHP Eotaxin-3 Gen. B Kit Eotaxin-3 \| Non-human primate Singleplex
V-PLEX NHP Eotaxin-3 Gen. B Kit Eotaxin-3 \| Non-human primate Singleplex
V-PLEX Plus NHP MDC Gen. B Kit MDC \| Non-human primate Singleplex
V-PLEX Plus NHP MCP-4 Gen. B Kit MCP-4 \| Non-human primate Singleplex
V-PLEX Plus NHP Eotaxin Gen. B Kit Eotaxin \| Non-human primate Singleplex
V-PLEX Plus Chemokine Panel 1 (NHP) Gen. B Kit Eotaxin, Eotaxin-3, IP-10, MCP-1, MCP-4, MDC, MIP-1α, MIP-1β, TARC \| Non-human primate Multiplex
V-PLEX NHP MDC Gen. B Kit MDC \| Non-human primate Singleplex
V-PLEX NHP MCP-4 Gen. B Kit MCP-4 \| Non-human primate Singleplex
V-PLEX NHP Eotaxin Gen. B Kit Eotaxin \| Non-human primate Singleplex
V-PLEX Chemokine Panel 1 (NHP) Gen. B Kit Eotaxin, Eotaxin-3, IP-10, MCP-1, MCP-4, MDC, MIP-1α, MIP-1β, TARC \| Non-human primate Multiplex
V-PLEX Plus NHP TARC Gen. B Kit TARC \| Non-human primate Singleplex
V-PLEX NHP TARC Gen. B Kit TARC \| Non-human primate Singleplex
V-PLEX Plus NHP IP-10 Gen. B Kit IP-10 \| Non-human primate Singleplex
V-PLEX NHP IP-10 Gen. B Kit IP-10 \| Non-human primate Singleplex
V-PLEX Plus Human MIP-1β Gen. B Kit MIP-1β \| Human Singleplex
V-PLEX Plus Human IL-2 Kit IL-2 \| Human Singleplex
V-PLEX Human IL-2 Kit IL-2 \| Human Singleplex
V-PLEX Plus Human IL-8 Kit IL-8 \| Human Singleplex
V-PLEX Human IL-8 Kit IL-8 \| Human Singleplex
V-PLEX Human VEGF Kit VEGF-A \| Human Singleplex
V-PLEX Human IL-17A Kit IL-17A \| Human Singleplex
V-PLEX Human IL-1α Kit IL-1α \| Human Singleplex
V-PLEX Plus Human IL-1α Kit IL-1α \| Human Singleplex
V-PLEX NHP GM-CSF Kit GM-CSF \| Non-human primate Singleplex
V-PLEX NHP VEGF Kit VEGF-A \| Non-human primate Singleplex
V-PLEX NHP IL-17A Kit IL-17A \| Non-human primate Singleplex
V-PLEX Plus NHP GM-CSF Kit GM-CSF \| Non-human primate Singleplex
V-PLEX Plus NHP VEGF Kit VEGF-A \| Non-human primate Singleplex
V-PLEX Plus NHP IL-17A Kit IL-17A \| Non-human primate Singleplex
V-PLEX Plus Human VEGF Kit VEGF-A \| Human Singleplex
V-PLEX Plus Human IL-17A Kit IL-17A \| Human Singleplex
V-PLEX Plus NHP IL-2 Kit IL-2 \| Non-human primate Singleplex
V-PLEX NHP IL-8 Kit IL-8 \| Non-human primate Singleplex
V-PLEX NHP IL-2 Kit IL-2 \| Non-human primate Singleplex
V-PLEX Plus NHP IL-8 Kit IL-8 \| Non-human primate Singleplex
V-PLEX NHP IL-6 Kit IL-6 \| Non-human primate Singleplex
V-PLEX NHP IL-16 Kit IL-16 \| Non-human primate Singleplex
V-PLEX NHP IL-7 Kit IL-7 \| Non-human primate Singleplex
V-PLEX Human TNF-β Kit TNF-β \| Human Singleplex
V-PLEX Human IL-16 Kit IL-16 \| Human Singleplex
V-PLEX Human IL-7 Kit IL-7 \| Human Singleplex
V-PLEX Human IL-6 Kit IL-6 \| Human Singleplex
V-PLEX Plus Human MCP-1 Gen. B Kit MCP-1 \| Human Singleplex
V-PLEX Human MIP-1β Gen. B Kit MIP-1β \| Human Singleplex
V-PLEX Human MCP-1 Gen. B Kit MCP-1 \| Human Singleplex
V-PLEX Plus NHP TNF-β Kit TNF-β \| Non-human primate Singleplex
V-PLEX Plus NHP IL-16 Kit IL-16 \| Non-human primate Singleplex
V-PLEX Plus NHP IL-7 Kit IL-7 \| Non-human primate Singleplex
V-PLEX Plus NHP IL-6 Kit IL-6 \| Non-human primate Singleplex
V-PLEX Plus Human TNF-β Kit TNF-β \| Human Singleplex
V-PLEX Plus Human IL-16 Kit IL-16 \| Human Singleplex
V-PLEX Plus Human IL-7 Kit IL-7 \| Human Singleplex
V-PLEX Plus Human IL-6 Kit IL-6 \| Human Singleplex
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V-PLEX NHP TNF-β Kit TNF-β \| Non-human primate Singleplex
V-PLEX Plus NHP IL-1β Kit IL-1β \| Non-human primate Singleplex
V-PLEX Plus Human IL-1β Kit IL-1β \| Human Singleplex
V-PLEX NHP IL-1β Kit IL-1β \| Non-human primate Singleplex
V-PLEX Human IL-1β Kit IL-1β \| Human Singleplex
V-PLEX Plus NHP IL-10 Kit IL-10 \| Non-human primate Singleplex
V-PLEX Plus Human IL-10 Kit IL-10 \| Human Singleplex
V-PLEX NHP IL-10 Kit IL-10 \| Non-human primate Singleplex
V-PLEX Human IL-10 Kit IL-10 \| Human Singleplex
V-PLEX Plus Human TNF-α Kit TNF-α \| Human Singleplex
V-PLEX Human TNF-α Kit TNF-α \| Human Singleplex
V-PLEX Plus Human MIP-1α Gen. B Kit MIP-1α \| Human Singleplex
V-PLEX Human MIP-1α Gen. B Kit MIP-1α \| Human Singleplex
V-PLEX Plus Human GM-CSF Kit GM-CSF \| Human Singleplex
V-PLEX Human GM-CSF Kit GM-CSF \| Human Singleplex
V-PLEX Cytokine Panel 1 NHP Kit GM-CSF, IL-5, IL-7, IL-12/IL-23p40, IL-15, IL-16, IL-17A, TNF-β, VEGF-A \| Non-human primate Multiplex
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V-PLEX Plus Human Cytokine 29-Plex Kit Eotaxin, Eotaxin-3, GM-CSF, IFN-γ, IL-1α, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-7, IL-8, IL-10, IL-12/IL-23p40, IL-12p70, IL-13, IL-15, IL-16, IL-17A, IP-10, MCP-1, MCP-4, MDC, MIP-1α, MIP-1β, TARC, TNF-α, TNF-β, VEGF-A \| Human Multiplex
V-PLEX Custom Human Biomarkers 1 C-Peptide, Eotaxin, Eotaxin-3, GIP (active), GLP-1 (active), Glucagon, GM-CSF, IFN-γ, IL-1α, IL-1β, IL-1RA, IL-2, IL-3, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, IL-10, IL-12/IL-23p40, IL-12p70, IL-13, IL-15, IL-16, IL-17A, IL-17A/F, IL-17B, IL-17C, IL-17D, Insulin, IP-10, Leptin, MCP-1, MCP-4, MDC, MIP-1α, MIP-1β, PP, TARC, TNF-α, TNF-β, TSLP, VEGF-A \| Human Multiplex		NEW
V-PLEX Custom NHP Biomarkers 1 C-Peptide, Eotaxin, Eotaxin-3, GIP (active), GLP-1 (active), Glucagon, GM-CSF, IFN-γ, IL-1β, IL-2, IL-5, IL-6, IL-7, IL-8, IL-10, IL-12/IL-23p40, IL-15, IL-16, IL-17A, Insulin, IP-10, MCP-1, MCP-4, MDC, MIP-1α, MIP-1β, PP, TARC, TNF-β, VEGF-A \| Non-human primate Multiplex		NEW
V-PLEX Custom Mouse Biomarkers IFN-γ, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-9, IL-10, IL-12p70, IL-15, IL-17A/F, IL-27p28/IL-30, IL-33, IP-10, KC/GRO, MCP-1, MIP-1α, MIP-2, TNF-α \| Mouse Multiplex		NEW
V-PLEX Plus Mouse TNF-α Kit TNF-α \| Mouse Singleplex		NEW
V-PLEX Plus Mouse IL-6 Kit IL-6 \| Mouse Singleplex		NEW
V-PLEX Plus Mouse IL-1β Kit IL-1β \| Mouse Singleplex		NEW
V-PLEX Plus Mouse IFN-γ Kit IFN-γ \| Mouse Singleplex		NEW
V-PLEX Mouse TNF-α Kit TNF-α \| Mouse Singleplex		NEW
V-PLEX Mouse IL-6 Kit IL-6 \| Mouse Singleplex		NEW
V-PLEX Mouse IL-1β Kit IL-1β \| Mouse Singleplex		NEW
V-PLEX Mouse IFN-γ Kit IFN-γ \| Mouse Singleplex		NEW
V-PLEX Plus Mouse IL-2 Kit IL-2 \| Mouse Singleplex		NEW
V-PLEX Mouse IL-2 Kit IL-2 \| Mouse Singleplex		NEW
V-PLEX Proinflammatory Panel 1 Mouse Kit IFN-γ, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-10, IL-12p70, KC/GRO, TNF-α \| Mouse Multiplex		NEW
V-PLEX Plus Proinflammatory Panel 1 Mouse Kit IFN-γ, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-10, IL-12p70, KC/GRO, TNF-α \| Mouse Multiplex		NEW
V-PLEX Plus Mouse IL-12p70 Kit IL-12p70 \| Mouse Singleplex		NEW
V-PLEX Plus Mouse IL-10 Kit IL-10 \| Mouse Singleplex		NEW
V-PLEX Plus Mouse IL-5 Kit IL-5 \| Mouse Singleplex		NEW
V-PLEX Plus Mouse IL-4 Kit IL-4 \| Mouse Singleplex		NEW
V-PLEX Mouse IL-12p70 Kit IL-12p70 \| Mouse Singleplex		NEW
V-PLEX Mouse IL-10 Kit IL-10 \| Mouse Singleplex		NEW
V-PLEX Mouse IL-5 Kit IL-5 \| Mouse Singleplex		NEW
V-PLEX Mouse IL-4 Kit IL-4 \| Mouse Singleplex		NEW
V-PLEX Plus NHP MIP-1β Gen. B Kit MIP-1β \| Non-human primate Singleplex
V-PLEX NHP MIP-1β Gen. B Kit MIP-1β \| Non-human primate Singleplex
V-PLEX Plus NHP MCP-1 Gen. B Kit MCP-1 \| Non-human primate Singleplex
V-PLEX NHP MCP-1 Gen. B Kit MCP-1 \| Non-human primate Singleplex
V-PLEX Plus NHP MIP-1α Gen. B Kit MIP-1α \| Non-human primate Singleplex
V-PLEX NHP MIP-1α Gen. B Kit MIP-1α \| Non-human primate Singleplex
V-PLEX Plus NHP Eotaxin-3 Gen. B Kit Eotaxin-3 \| Non-human primate Singleplex
V-PLEX NHP Eotaxin-3 Gen. B Kit Eotaxin-3 \| Non-human primate Singleplex
V-PLEX Plus NHP MDC Gen. B Kit MDC \| Non-human primate Singleplex
V-PLEX Plus NHP MCP-4 Gen. B Kit MCP-4 \| Non-human primate Singleplex
V-PLEX Plus NHP Eotaxin Gen. B Kit Eotaxin \| Non-human primate Singleplex
V-PLEX Plus Chemokine Panel 1 (NHP) Gen. B Kit Eotaxin, Eotaxin-3, IP-10, MCP-1, MCP-4, MDC, MIP-1α, MIP-1β, TARC \| Non-human primate Multiplex
V-PLEX NHP MDC Gen. B Kit MDC \| Non-human primate Singleplex
V-PLEX NHP MCP-4 Gen. B Kit MCP-4 \| Non-human primate Singleplex
V-PLEX NHP Eotaxin Gen. B Kit Eotaxin \| Non-human primate Singleplex
V-PLEX Chemokine Panel 1 (NHP) Gen. B Kit Eotaxin, Eotaxin-3, IP-10, MCP-1, MCP-4, MDC, MIP-1α, MIP-1β, TARC \| Non-human primate Multiplex
V-PLEX Plus NHP TARC Gen. B Kit TARC \| Non-human primate Singleplex
V-PLEX NHP TARC Gen. B Kit TARC \| Non-human primate Singleplex
V-PLEX Plus NHP IP-10 Gen. B Kit IP-10 \| Non-human primate Singleplex
V-PLEX NHP IP-10 Gen. B Kit IP-10 \| Non-human primate Singleplex
V-PLEX Plus Human MIP-1β Gen. B Kit MIP-1β \| Human Singleplex
V-PLEX Plus Human IL-2 Kit IL-2 \| Human Singleplex
V-PLEX Human IL-2 Kit IL-2 \| Human Singleplex
V-PLEX Plus Human IL-8 Kit IL-8 \| Human Singleplex
V-PLEX Human IL-8 Kit IL-8 \| Human Singleplex
V-PLEX Human VEGF Kit VEGF-A \| Human Singleplex
V-PLEX Human IL-17A Kit IL-17A \| Human Singleplex
V-PLEX Human IL-1α Kit IL-1α \| Human Singleplex
V-PLEX Plus Human IL-1α Kit IL-1α \| Human Singleplex
V-PLEX NHP GM-CSF Kit GM-CSF \| Non-human primate Singleplex
V-PLEX NHP VEGF Kit VEGF-A \| Non-human primate Singleplex
V-PLEX NHP IL-17A Kit IL-17A \| Non-human primate Singleplex
V-PLEX Plus NHP GM-CSF Kit GM-CSF \| Non-human primate Singleplex
V-PLEX Plus NHP VEGF Kit VEGF-A \| Non-human primate Singleplex
V-PLEX Plus NHP IL-17A Kit IL-17A \| Non-human primate Singleplex
V-PLEX Plus Human VEGF Kit VEGF-A \| Human Singleplex
V-PLEX Plus Human IL-17A Kit IL-17A \| Human Singleplex
V-PLEX Plus NHP IL-2 Kit IL-2 \| Non-human primate Singleplex
V-PLEX NHP IL-8 Kit IL-8 \| Non-human primate Singleplex
V-PLEX NHP IL-2 Kit IL-2 \| Non-human primate Singleplex
V-PLEX Plus NHP IL-8 Kit IL-8 \| Non-human primate Singleplex
V-PLEX NHP IL-6 Kit IL-6 \| Non-human primate Singleplex
V-PLEX NHP IL-16 Kit IL-16 \| Non-human primate Singleplex
V-PLEX NHP IL-7 Kit IL-7 \| Non-human primate Singleplex
V-PLEX Human TNF-β Kit TNF-β \| Human Singleplex
V-PLEX Human IL-16 Kit IL-16 \| Human Singleplex
V-PLEX Human IL-7 Kit IL-7 \| Human Singleplex
V-PLEX Human IL-6 Kit IL-6 \| Human Singleplex
V-PLEX Plus Human MCP-1 Gen. B Kit MCP-1 \| Human Singleplex
V-PLEX Human MIP-1β Gen. B Kit MIP-1β \| Human Singleplex
V-PLEX Human MCP-1 Gen. B Kit MCP-1 \| Human Singleplex
V-PLEX Plus NHP TNF-β Kit TNF-β \| Non-human primate Singleplex
V-PLEX Plus NHP IL-16 Kit IL-16 \| Non-human primate Singleplex
V-PLEX Plus NHP IL-7 Kit IL-7 \| Non-human primate Singleplex
V-PLEX Plus NHP IL-6 Kit IL-6 \| Non-human primate Singleplex
V-PLEX Plus Human TNF-β Kit TNF-β \| Human Singleplex
V-PLEX Plus Human IL-16 Kit IL-16 \| Human Singleplex
V-PLEX Plus Human IL-7 Kit IL-7 \| Human Singleplex
V-PLEX Plus Human IL-6 Kit IL-6 \| Human Singleplex
V-PLEX Plus Cytokine Panel 1 NHP Kit GM-CSF, IL-5, IL-7, IL-12/IL-23p40, IL-15, IL-16, IL-17A, TNF-β, VEGF-A \| Non-human primate Multiplex
V-PLEX NHP TNF-β Kit TNF-β \| Non-human primate Singleplex
V-PLEX Plus NHP IL-1β Kit IL-1β \| Non-human primate Singleplex
V-PLEX Plus Human IL-1β Kit IL-1β \| Human Singleplex
V-PLEX NHP IL-1β Kit IL-1β \| Non-human primate Singleplex
V-PLEX Human IL-1β Kit IL-1β \| Human Singleplex
V-PLEX Plus NHP IL-10 Kit IL-10 \| Non-human primate Singleplex
V-PLEX Plus Human IL-10 Kit IL-10 \| Human Singleplex
V-PLEX NHP IL-10 Kit IL-10 \| Non-human primate Singleplex
V-PLEX Human IL-10 Kit IL-10 \| Human Singleplex
V-PLEX Plus Human TNF-α Kit TNF-α \| Human Singleplex
V-PLEX Human TNF-α Kit TNF-α \| Human Singleplex
V-PLEX Plus Human MIP-1α Gen. B Kit MIP-1α \| Human Singleplex
V-PLEX Human MIP-1α Gen. B Kit MIP-1α \| Human Singleplex
V-PLEX Plus Human GM-CSF Kit GM-CSF \| Human Singleplex
V-PLEX Human GM-CSF Kit GM-CSF \| Human Singleplex
V-PLEX Cytokine Panel 1 NHP Kit GM-CSF, IL-5, IL-7, IL-12/IL-23p40, IL-15, IL-16, IL-17A, TNF-β, VEGF-A \| Non-human primate Multiplex
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Galectin-9, a Player in Cytokine Release Syndrome and a Surrogate Diagnostic Biomarker in SARS-CoV-2 Infection

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