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U-PLEX Microbiome Combo 1 (human)

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U-PLEX Combos offer popular panels of biomarkers that have been grouped together for convenient ordering. They have been tested for multiplex compatibility and are fulfilled as a kit. The U-PLEX Microbiome Combo 1 (human) combines assays for 7 biomarkers that may be influenced by the gut microbiome (Table 1). The assays can be used for quantitative measurements in the sample types listed in the "Specifications" tab below, and offer detection limits (LLODs) in the sub- to low pg/mL range. This Combo is provided on 2 plates.

Table 1. List of analytes and typical detection limits

Analyte	LLOD - ULOD	units
Ghrelin (total)	1.7 - 2,710	pg/mL
GLP-1 (total)	0.59 - 576	pM
Glucagon	0.13 - 156	pM
Insulin	0.32 - 736	μIU/mL
Leptin	14 - 47,500	pg/mL
PP	0.19 - 1,830	pg/mL
PYY (total)	2.7 - 2,260	pg/mL

Specifications
Kit Contents
References
Documentation

Analyte(s)		Ghrelin (total), GLP-1 (total), Glucagon, Insulin, Leptin, PP, PYY (total)
Species		Human
Plate Type		96-well
U-PLEX Group Compatibility		Metabolic Group 1
Instrument(s)		MESO SECTOR S 600MM , MESO QuickPlex SQ 120MM , MESO QuickPlex Q 60MM , MESO SECTOR S 600 , MESO QuickPlex SQ 120 , SECTOR Imager 6000 , SECTOR Imager 2400
Sample Type		EDTA Plasma, P800 Plasma, Serum
Usage Statement		For Research Use Only. Not for use in diagnostic procedures.
Storage Statement(s)		Please refer to the product insert for the storage conditions of individual kit components.
Storage Condition		Multi-Component
Schedule B Code		3822.19.0000

Kit Contents for Catalog No. K15441K-1

Product Description

Storage

Quantity per Kit

Human Microbiome Combo 1, Box 1 of 2 (1 PL)

Multi-Component

1 each
(1 plate size)

U-PLEX Linker Set, 6-Assay (300 µL)	2-8 °C	1 each (1 vial)
U-PLEX GLP-1 (total) Antibody Set	2-8 °C	1 each (1 plate size)
U-PLEX Ghrelin (total) Antibody Set	2-8 °C	1 each (1 plate size)
U-PLEX Human Leptin Antibody Set (1 Plate Size)	2-8 °C	1 each (1 plate size)
U-PLEX Human PP Antibody Set (1 Plate Size)	2-8 °C	1 each (1 plate size)
U-PLEX Human PYY (total) Antibody Set (1 Plate Size)	2-8 °C	1 each (1 plate size)
U-PLEX Human Insulin Antibody Set (1 Plate Size)	2-8 °C	1 each (1 plate size)
Calibrator 13	2-8 °C	1 vial (1 vial)
Calibrator 15	2-8 °C	1 vial (1 vial)
U-PLEX 6-Assay, 96-Well SECTOR Plate	2-8 °C	1 each (1 plate)
U-PLEX Stop Solution	2-8 °C	1 bottle (40 mL)
Diluent 11	≤-10 °C	1 bottle (10 mL)
Diluent 13	≤-10 °C	1 bottle (10 mL)
MSD GOLD Read Buffer B	RT	1 bottle (18 mL)
Aprotinin	2-8 °C	1 vial (50 μL)

Human Microbiome Combo 1, Box 2 of 2 (1 PL)

Multi-Component

1 each
(1 plate size)

U-PLEX Linker Set, 1-Assay (300 μL)	2-8 °C	1 each (1 vial)
U-PLEX Glucagon Antibody Set	2-8 °C	1 each (1 plate size)
Calibrator 13	2-8 °C	1 vial (1 vial)
U-PLEX 2-Assay, 96-Well SECTOR Plate	2-8 °C	1 each (1 plate)
U-PLEX Stop Solution	2-8 °C	1 bottle (40 mL)
Diluent 11	≤-10 °C	1 bottle (10 mL)
Diluent 13	≤-10 °C	1 bottle (10 mL)
MSD GOLD Read Buffer B	RT	1 bottle (18 mL)
Aprotinin	2-8 °C	1 vial (50 μL)

Kit Contents for Catalog No. K15441K-2

Product Description

Storage

Quantity per Kit

Human Microbiome Combo 1, Box 1 of 2 (5 PL)

Multi-Component

1 each
(5 plate size)

U-PLEX Linker Set, 6-Assay (1.8 mL)	2-8 °C	1 each (1 vial)
U-PLEX GLP-1 (total) Antibody Set	2-8 °C	1 each (5 plate size)
U-PLEX Ghrelin (total) Antibody Set	2-8 °C	1 each (5 plate size)
U-PLEX Human Leptin Antibody Set (5 Plate Size)	2-8 °C	1 each (5 plate size)
U-PLEX Human PP Antibody Set (5 Plate Size)	2-8 °C	1 each (5 plate size)
U-PLEX Human PYY (total) Antibody Set (5 Plate Size)	2-8 °C	1 each (5 plate size)
U-PLEX Human Insulin Antibody Set (5 Plate Size)	2-8 °C	1 each (5 plate size)
Calibrator 13	2-8 °C	5 vial (1 vial)
Calibrator 15	2-8 °C	5 vial (1 vial)
U-PLEX 6-Assay, 96-Well SECTOR Plate	2-8 °C	5 each (1 plate)
U-PLEX Stop Solution	2-8 °C	1 bottle (40 mL)
Diluent 11	≤-10 °C	1 bottle (50 mL)
Diluent 13	≤-10 °C	1 bottle (50 mL)
MSD GOLD Read Buffer B	RT	1 bottle (90 mL)
Aprotinin	2-8 °C	1 vial (250 μL)

Human Microbiome Combo 1, Box 2 of 2 (5 PL)

Multi-Component

1 each
(5 plate size)

U-PLEX Linker Set, 1-Assay (1.8 mL)	2-8 °C	1 each (1 vial)
U-PLEX Glucagon Antibody Set	2-8 °C	1 each (5 plate size)
Calibrator 13	2-8 °C	5 vial (1 vial)
U-PLEX 2-Assay, 96-Well SECTOR Plate	2-8 °C	5 each (1 plate)
U-PLEX Stop Solution	2-8 °C	1 bottle (40 mL)
Diluent 11	≤-10 °C	1 bottle (50 mL)
Diluent 13	≤-10 °C	1 bottle (50 mL)
MSD GOLD Read Buffer B	RT	1 bottle (90 mL)
Aprotinin	2-8 °C	1 vial (250 μL)

Kit Contents for Catalog No. K15441K-4

Product Description

Storage

Quantity per Kit

Human Microbiome Combo 1, Box 1 of 2 (25 PL)

Multi-Component

1 each
(25 plate size)

U-PLEX Linker Set, 6-Assay (1.8 mL)	2-8 °C	5 each (1 vial)
U-PLEX GLP-1 (total) Antibody Set	2-8 °C	5 each (5 plate size)
U-PLEX Ghrelin (total) Antibody Set	2-8 °C	5 each (5 plate size)
U-PLEX Human Leptin Antibody Set (5 Plate Size)	2-8 °C	5 each (5 plate size)
U-PLEX Human PP Antibody Set (5 Plate Size)	2-8 °C	5 each (5 plate size)
U-PLEX Human PYY (total) Antibody Set (5 Plate Size)	2-8 °C	5 each (5 plate size)
U-PLEX Human Insulin Antibody Set (5 Plate Size)	2-8 °C	5 each (5 plate size)
Calibrator 13	2-8 °C	25 vial (1 vial)
Calibrator 15	2-8 °C	25 vial (1 vial)
U-PLEX 6-Assay, 96-Well SECTOR Plate	2-8 °C	25 each (1 plate)
U-PLEX Stop Solution	2-8 °C	5 bottle (40 mL)
Diluent 11	≤-10 °C	5 bottle (50 mL)
Diluent 13	≤-10 °C	5 bottle (50 mL)
MSD GOLD Read Buffer B	RT	5 bottle (90 mL)
Aprotinin	2-8 °C	5 vial (250 μL)

Human Microbiome Combo 1, Box 2 of 2 (25 PL)

Multi-Component

1 each
(25 plate size)

U-PLEX Linker Set, 1-Assay (1.8 mL)	2-8 °C	5 each (1 vial)
U-PLEX Glucagon Antibody Set	2-8 °C	5 each (5 plate size)
Calibrator 13	2-8 °C	25 vial (1 vial)
U-PLEX 2-Assay, 96-Well SECTOR Plate	2-8 °C	25 each (1 plate)
U-PLEX Stop Solution	2-8 °C	5 bottle (40 mL)
Diluent 11	≤-10 °C	5 bottle (50 mL)
Diluent 13	≤-10 °C	5 bottle (50 mL)
MSD GOLD Read Buffer B	RT	5 bottle (90 mL)
Aprotinin	2-8 °C	5 vial (250 μL)

Kit Contents for Catalog No. K15441K-21

Product Description	Storage	Quantity per Kit
Human Microbiome Combo 1, Box 1 of 2 (1 PL)	Multi-Component	1 each (1 each)

Human Microbiome Combo 1, Box 2 of 2 (1 PL)	Multi-Component	1 each (1 each)

Kit Contents for Catalog No. K15441K-22

Product Description	Storage	Quantity per Kit
Human Microbiome Combo 1, Box 1 of 2 (5 PL)	Multi-Component	1 each (5 each)

Human Microbiome Combo 1, Box 2 of 2 (5 PL)	Multi-Component	1 each (5 each)

Kit Contents for Catalog No. K15441K-24

Product Description	Storage	Quantity per Kit
Human Microbiome Combo 1, Box 1 of 2 (25 PL)	Multi-Component	1 each (25 each)

Human Microbiome Combo 1, Box 2 of 2 (25 PL)	Multi-Component	1 each (25 each)

Related Products

Product Name	Applications	Species	Plate Type
U-PLEX TH17 Combo 1 (human)	Cytokines & Chemokines, Immunology/Inflammation	Human	96-well
U-PLEX TH17 Combo 2 (human)	Cytokines & Chemokines, Immunology/Inflammation	Human	96-well

Order Details

K15441K

Select your instrument:

S 600

SQ 120

Q 60

Catalog No

Size

Price in USD

Qty

K15441K-1

1 plate size

$2,413.00

Planned: 3 Day Delivery

K15441K-2

5 plate size

$10,179.00

Planned: 3 Day Delivery

K15441K-4

25 plate size

$45,807.00

Planned: 3 Day Delivery

K15441K-21

1 plate size

$2,413.00

Usually ships in 1-3 days

K15441K-22

5 plate size

$10,179.00

Usually ships in 1-3 days

K15441K-24

25 plate size

$45,807.00

Usually ships in 1-3 days

Customize

Contact Information

Customer Service/Orders
1-240-314-2795

5:00 a.m. to 8:00 p.m.
US Eastern Time

Email

Scientific/Technical Support
1-240-314-2798

8:30 a.m. to 5:30 p.m.
US Eastern Time

Email

Instrument Support
1-301-947-2057

8:30 a.m. - 5:30 p.m.
US Eastern Time

Email

Company Headquarters
1-240-314-2600
1601 Research Blvd.
Rockville, Maryland 20850-3173
USA

Title	Journal	Year
Islet Autoantibody Standardization Program: interlaboratory comparison of insulin autoantibody assay performance in 2018 and 2020 workshops Ilaria Marzinotto, David L Pittman, Alistair J K Williams, Anna E Long, Peter Achenbach, Michael Schlosser, Beena Akolkar, William E Winter, Vito Lampasona; participating laboratories	Diabetologia	2023
Leptin levels are associated with multiple sclerosis risk Biström M, Hultdin J, Andersen O, Alonso-Magdalena L, Jons D, Gunnarsson M, Vrethem M, Sundström P	Multiple Sclerosis	2020
Genetic Deletion and Pharmacological Inhibition of Phosphodiesterase 10A Protects Mice From Diet-Induced Obesity and Insulin Resistance. Nawrocki AR, Rodriguez CG, Toolan DM, Price O, Henry M, Forrest G, Szeto D, Keohane CA, Pan Y, Smith KM, Raheem IT, Cox CD, Hwa J, Renger JJ, Smith SM.	Diabetes	2014
A multi-biomarker score measures rheumatoid arthritis disease activity in the BeSt study. Hirata S, Dirven L, Shen Y, Centola M, Cavet G, Lems WF, Tanaka Y, Huizinga TW, Allaart CF.	Rheumatology (Oxford)	2013
Beneficial effects of parenteral GLP-1 delivery by cell therapy in insulin-deficient streptozotocin diabetic mice. Vasu S, Moffett RC, McCluskey JT, Hamid MH, Irwin N, Flatt PR.	Gene Ther.	2013
View All

Product Inserts		U-PLEX Metabolic Group 1 (human) Multiplex Insert
Datasheets		U-PLEX Human Ghrelin (total) U-PLEX Human GLP-1 (total) U-PLEX Human Glucagon U-PLEX Human Insulin U-PLEX Human Leptin U-PLEX Human PP U-PLEX Human PYY-total
Product Highlights		U-PLEX Platform Highlights
SDS		Biotin-conjugated Antibodies Safety Data Sheet Diluent 10, Diluent 11, Diluent 12, Diluent 13, Diluent 15, Diluent 16 and Diluent 17 MSD Calibrators and Controls MSD GOLD Read Buffer B U-PLEX Linker Set

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U-PLEX Microbiome Combo 1 (human)

Kit Contents for Catalog No. K15441K-1

Kit Contents for Catalog No. K15441K-2

Kit Contents for Catalog No. K15441K-4

Kit Contents for Catalog No. K15441K-21

Kit Contents for Catalog No. K15441K-22

Kit Contents for Catalog No. K15441K-24

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K15441K

S 600

SQ 120

Q 60

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