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Rat Clusterin Kit
Clusterin is a glycoprotein that is found in most mammalian tissues. The localized over-expression of clusterin at sites of tissue damage or stress indicates that clusterin acts as a molecular chaperone displaying cytoprotective characteristics. In addition, the marked induction of clusterin in several renal disease states suggest that clusterin may be a putative biochemical marker of kidney damage and disease. The Rat Clusterin Kit provides assay-specific components for the quantitative determination of endogenous clusterin in rat urine, serum, plasma and cell supernatant.

Product Detail
Application Kidney Markers, Toxicology
Analyte Clusterin
Species Rat
Instrument SI2400, SI6000
Plate Type 96-well singleplex
 
Documents
Title Lot Number
doc Product insert
doc Data sheet
doc Certificate of analysis K0040138
doc Certificate of analysis K0040163
Product Options
Catalog No. Product Name Size
K153MGC-4 Rat Clusterin Kit 25 plates
K153MGC-2 Rat Clusterin Kit 5 plates
Additional Information
Related Publications Journal Year  
(2011) Nephrotoxicity of hexachloro-1:3-butadiene in the male Hanover Wistar rat; correlation of minimal histopathological changes with biomarkers of renal injury.
Swain, A., Turton, J., Scudamore, C., Maguire, D., Pereira, I., Freitas, S., Smyth, R., Munday, M., Stamp, C., Gandhi, M., Sondh, S., Ashall, H., Francis, I., Woodfine, J., Bowles, J., York, M.
J Appl Toxicol. 2011
Comparison of the course of biomarker changes and kidney injury in a rat model of drug-induced acute kidney injury.
Sasaki, D., Yamada, A., Umeno, H., Kurihara, H., Nakatsuji, S., Fujihira, S., Tsubota, K., Ono, M., Moriguchi, A., Watanabe, K., Seki, J.
Biomarkers. 2011
Comparative profile of commercially available urinary biomarkers in preclinical drug-induced kidney injury and recovery in rats.
Rouse, R.L., Zhang, J., Stewart, S.R., Rosenzweig, B.A., Espandiari, P., Sadrieh, N.K.
Kidney Int. 2010
Renal biomarker changes associated with hyaline droplet nephropathy in rats are time and potentially compound dependent.
Brott DA, Bentley P, Nadella MV, Thurman D, Fikes J, Cheatham L, McGrath F, Luo W, Kinter LB.
Toxicology 2012
Underestimation of urinary biomarker-to-creatinine ratio resulting from age-related gain in muscle mass in rats.
Tonomura Y, Morikawa Y, Takagi S, Torii M, Matsubara M.
Toxicology 2012

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Price and Availability
Price Please call for price
Size 1 plate
Catalog No. K153MGC-1
Availability Usually ships in 1-3 days

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