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Human YKL-40 Kit
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| YKL-40 is a 40 kDa inflammatory glycoprotein involved in the activation of the innate immune system and extracellular matrix remodeling. YKL-40 is secreted by macrophages, neutrophils, chondrocytes, vascular smooth muscle, and hepatic stellate cells. Elevated serum YKL-40 levels are associated with the presence and extent of coronary artery disease (CAD) and even higher YKL-40 levels have been documented in patients with myocardial infarction and both type 1 and type 2 diabetes. Enhanced expression of YKL-40 is observed in macrophages and smooth muscle cells in atherosclerotic plaques. In endothelial dysfunction, elevated YKL-40 levels seem to be involved in cell migration, reorganization, and tissue remodeling in response to endothelial damage. Therefore, YKL-40 may play a role in multiple pathogenic processes related to inflammation, extracellular tissue remodeling, fibrosis, and the metastatic and angiogenic invasiveness of many solid tumors. The Human YKL-40 Kit provides assay-specific components for the quantitative determination of endogenous YKL-40 in human serum, plasma and cell supernatant. |
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| Price |
Please call for price |
| Size |
1 plate |
| Catalog No. |
K151NHD-1 |
| Availability |
Usually ships within 3 weeks |
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K151NHD-1
