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Human IL-18 Kit
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| Interleukin 18 (IL-18) is an 18-kDa cytokine and a co-stimulatory factor that is produced in Kuppfer cells, activated macrophages, keratinocytes, and intestinal epithelial cells. One of the main functions of IL-18 is to promote the production of IFN-γ from T and NK cells, particularly in the presence of IL-12p70. IL-18 also promotes the secretion of other proinflammatory cytokines like TNF-α, IL-1β, and GM-CSF that enhance the migration and activation of neutrophils during microbial infections. In addition, IL-18 enhances cytotoxic activity and proliferation of CD8+ T and NK cells. IL-18 has also been shown to stimulate the production of IL-13 and other Th2 cytokines. Dysregulation of IL-18 may therefore contribute to inflammatory-associated disorders, unchecked infections, autoimmune diseases such as rheumatoid arthritis, acute and chronic kidney injury, cancer, and pathogenic conditions related to metabolic syndrome. The Human IL-18 Kit provides the assay-specific components for the quantitative determination of endogenous IL-18 in human serum, plasma and cell supernatant. |
Cluster Analysis of Placental Inflammatory Proteins Can Distinguish Preeclampsia from Preterm Labor and Premature Membrane Rupture in Singleton Deliveries Less Than 28 Weeks of Gestation.
Faupel-Badger, J.M., Fichorova, R.N., Allred, E.N., Hecht, J.L., Dammann, O., Leviton, A., McElrath, T.F.
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Am J Reprod Immunol. |
2011 |
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Urine Biomarkers Predict Acute Kidney Injury and Mortality in Very Low Birth Weight Infants.
Askenazi, D.J., Montesanti, A., Hunley, H., Koralkar, R., Pawar, P., Shuaib, F., Liwo, A., Devarajan, P., Ambalavanan, N.
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J Pediatr. |
2011 |
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| Price |
Please call for price |
| Size |
1 plate |
| Catalog No. |
K151MCD-1 |
| Availability |
Usually ships within 3 weeks |
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K151MCD-1
