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K15011B-1
Human TH1/TH2 7-Plex Tissue Culture Kit
The Human TH1/TH2 7-Plex Tissue Culture Kit provides assay-specific components for the simultaneous quantitative determination of both natural and recombinant human IFN-γ, IL-2, IL-4, IL-5, IL-10, IL-12p70, and IL-13 in tissue culture supernatant.
Product Detail
Application
Cytokines & Chemokines
Analyte
IFN-γ, IL-10, IL-12 p70, IL-13, IL-2, IL-4, IL-5
Species
Human
Instrument
SI2400
,
SI6000
Plate Type
96
-well
multiplex
Documents
Title
Lot Number
Product insert
Product Options
Catalog No.
Product Name
Size
K15011B-4
Human TH1/TH2 7-Plex Tissue Culture Kit
25 plates
K15011B-2
Human TH1/TH2 7-Plex Tissue Culture Kit
5 plates
Additional Information
Related Publications
Journal
Year
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High plasma interleukin-18 levels mark the acute phase of hepatitis C virus infection.
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J Infect Dis.
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Price and Availability
Price
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Size
1 plate
Catalog No.
K15011B-1
Availability
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Related Publications
Journal
Year
Short-term walnut consumption increases circulating total adiponectin and apolipoprotein A concentrations, but does not affect markers of inflammation or vascular injury in obese humans with the metabolic syndrome: data from a double-blinded, randomized, placebo-controlled study.
Aronis, K.N., Vamvini, M.T., Chamberland, J.P., Sweeney, L.L., Brennan, A.M., Magkos, F., Mantzoros, C.S.
Metabolism.
2011
Mycobacterium tuberculosis infection induces non-apoptotic cell death of human dendritic cells.
Ryan, R.C., O'Sullivan, M.P., Keane, J.
BMC Microbiol.
2011
MTRX1011A, a humanized anti-CD4 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: A Phase I randomized, double-blind, placebo-controlled study incorporating pharmacodynamic biomarker assessments.
Scheerens, H., Su, Z., Irving, B., Townsend, M.J., Zheng, Y., Stefanich, E., Chindalore, V., Bingham, C.O. 3rd, Davis, J.C. Jr.
Arthritis Res Ther.
2011
Placental growth factor and soluble c-kit receptor dynamics characterize the cytokine signature of imatinib in prostate cancer and bone metastases.
Mathew, P., Wen, S., Morita, S., Thall, P.F.
J Interferon Cytokine Res.
2011
High plasma interleukin-18 levels mark the acute phase of hepatitis C virus infection.
Chattergoon, M.A., Levine, J.S., Latanich, R., Osburn, W.O., Thomas, D.L., Cox, A.L.
J Infect Dis.
2011
Immediate and long-term effects of addition of exercise to a 16-week very low calorie diet on low-grade inflammation in obese, insulin-dependent type 2 diabetic patients.
Snel, M., Diepen, J.A., Stijnen, T., Pijl, H., Romijn, J.A., Edo Meinders, A., Voshol, P., Jazet, I.M.
Food Chem Toxicol.
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Cluster Analysis of Placental Inflammatory Proteins Can Distinguish Preeclampsia from Preterm Labor and Premature Membrane Rupture in Singleton Deliveries Less Than 28 Weeks of Gestation.
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Am J Reprod Immunol.
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Neonatal Cytokine Profile in the Airway Mucosal Lining Fluid is skewed by Maternal Atopy.
Folsgaard, N.V., Chawes, B.L., Rasmussen, M.A., Bischoff, A.L., Carson, C.G., Stokholm, J., Pedersen, L., Hansel, T.T., Bønnelykke, K., Brix, S., Bisgaard, H.
Am J Respir Crit Care Med.
2011
Cigarette smoke increases TLR4 and TLR9 expression and induces cytokine production from CD8+ T cells in chronic obstructive pulmonary disease.
Nadigel, J., Prefontaine, D., Baglole, C.J., Bourbeau, J., Maltais, F., Eidelman, D.H., Hamid, Q.
Respir Res.
2011
Mitochondrial mutagenesis correlates with the local inflammatory environment in arthritis.
Harty, L.C., Biniecka, M., O’Sullivan, J., Fox, E., Mulhall, K., Veale, D.J., Fearon, U.
Ann Rheum Dis.
2011
Surface molecules on stimulated plasmacytoid dendritic cells are sufficient to cross-activate resting myeloid dendritic cells.
Cantisani, R., Sammicheli, C., Tavarini, S., D'Oro, U., Wack, A., Piccioli, D.
Hum Immunol.
2011
Multiplex measurement of proinflammatory cytokines in human serum: Comparison of the Meso Scale Discovery electrochemiluminescence assay and the Cytometric Bead Array.
Dabitao, D., Margolick, J.B., Lopez, J., Bream, J.H.
J Immunol Methods
2011
Tryptophan catabolism in females with irritable bowel syndrome: relationship to interferon-gamma, severity of symptoms and psychiatric co-morbidity.
Fitzgerald, P., Cassidy Eugene, M., Clarke, G., Scully, P., Barry, S., Quigley Eamonn, M.M., Shanahan, F., Cryan, J., Dinan, T. G.
Neurogastroenterol Motil.
2008
TLR7 Agonist 852A Inhibition of Tumor Cell Proliferation Is Dependent on Plasmacytoid Dendritic Cells and Type I IFN.
Inglefield, J.R., Dumitru, C.D., Alkan, S.S., Gibson, S.J., Lipson, K.E., Tomai, M.A., Larson, C.J., Vasilakos, J.P.
J Interferon Cytokine Res.
2008
The anthrax vaccine adsorbed vaccine generates protective antigen (PA)-Specific CD4+ T cells with a phenotype distinct from that of naive PA T cells.
Kwok, W.W., Yang, J., James, E., Bui, J., Huston, L., Wiesen, A.R., Roti, M.
Infect Immun.
2008
The antileukemia activity of a human anti-CD40 antagonist antibody, HCD122, on human chronic lymphocytic leukemia cells.
Luqman, M., Klabunde, S., Lin, K., Georgakis, G.V., Cherukuri, A., Holash, J., Goldbeck, C., Xu, X., Kadel, E.E. 3rd, Lee, S.H., Aukerman, S.L., Jallal, B., Aziz, N., Weng, W.K., Wierda, W., O'Brien, S., Younes, A.
Blood
2008
Mutual antagonistic relationship between prostaglandin E(2) and IFN-gamma: Implications for rheumatoid arthritis.
Mathieu, M.C., Lord-Dufour, S., Bernier, V., Boie, Y., Burch, J.D., Clark, P., Denis, D., Han, Y., Mortimer, J.R., Therien, A.G.
Eur J Immunol.
2008
Healthy human subjects have CD4+ T cells directed against H5N1 influenza virus.
Roti, M., Yang, J., Berger, D., Huston, L., James, E.A., Kwok, W.W.
J Immunol Methods
2008
Impaired dendritic cell maturation and cytokine production in patients with chronic mucocutanous candidiasis with or without APECED.
Ryan, K.R., Hong, M., Arkwright, P.D., Gennery, A.R., Costigan, C., Dominguez, M., Denning, D., McConnell, V., Cant, A.J., Abinun, M., Spickett, G.P., Lilic, D.
Clin Exp Immunol.
2008
Coligation of the Hepatitis C Virus Receptor CD81 with CD28 Primes Naive T Lymphocytes to Acquire Type 2 Effector Function.
Serra, A., Nuti, S., Tavarini, S., Sammicheli, C., Rosa, D., Saletti, G., Soldaini, E., Abrignani, S., Wack, A.
J Immunol Methods
2008
Concurrent decrease in IL-10 with development of immune-related adverse events in a patient treated with anti-CTLA-4 therapy.
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Cancer Immun.
2008
Simultaneous Detection of Eight Analytes in Human Serum by Two Commercially Available Platforms for Multiplex Cytokine Analysis.
Toedter, G., Hayden, K., Wagner, C., Brodmerkel, C.
Clin Vaccine Immunol.
2008
TLR-TLR cross talk in human PBMC resulting in synergistic and antagonistic regulation of type-1 and 2 interferons, IL-12 and TNF-alpha.
Ghosh, T.K., Michelson, D.J., Solberg, J.C., Lipson, K.E., Inglefield, J.R., Alkan, S.S.
Int Immunopharmacol.
2007
Ovarian cancer cell-derived migration inhibitory factor enhances tumor growth, progression, and angiogenesis.
Hagemann, T., Robinson, S.C., Thompson, R.G., Charles, K., Kulbe, H., Balkwill, F.R.
Mol Cancer Ther.
2007
Staphylococcus aureus enterotoxin B, protein A, and lipoteichoic acid stimulations in nasal polyps.
Patou, J., Gevaert, P., Van Zele, T., Holtappels, G., van Cauwenberge, P., Bachert, C.
J Allergy Clin Immunol.
2007
Use of a cytokine gene expression signature in lung adenocarcinoma and the surrounding tissue as a prognostic classifier.
Seike, M., Yanaihara, N., Bowman, E.D., Zanetti, K.A., Budhu, A., Kumamoto, K., Mechanic, L.E., Matsumoto, S., Yokota, J., Shibata, T., Sugimura, H., Gemma, A., Kudoh, S., Wang, X.W., Harris, C.C.
J Natl Cancer Inst.
2007
Trichomonas vaginalis Lipophosphoglycan Triggers a Selective Upregulation of Cytokines by Human Female Reproductive Tract Epithelial Cells.
Fichorova, R.N., Trifonova, R.T., Gilbert, R.O., Costello, C.E., Hayes, G.R., Lucas, J.J., Singh, B.N.
Infection and Immunity.
2006
Selective leukemic-cell killing by a novel functional class of thalidomide analogs.
Ge, Y., Montano, I., Rustici, G., Freebern, W.J., Haggerty, C.M., Cui, W., Ponciano-Jackson, D., Chandramouli, G.V., Gardner, E.R., Figg, W.D., Abu-Asab, M., Tsokos, M., Jackson, S.H., Gardner. K.
Blood
2006
Toll-like receptor (TLR) 2-9 agonists-induced Cytokines & Chemokines: I. Comparison with T cell receptor-induced responses.
Ghosh, T.K., Michelson, D.J., Fink, J., Solberg, J.C., Inglefield, J.R., Hook, D., Gupta, S.K., Gibson, S., Alkan, S.S.
Cell Immunol.
2006
Predictors of elevated nuclear factor-kappaB-dependent genes in obstructive sleep apnea syndrome.
Ryan, S., Taylor, C.T., McNicholas, W.T.
Am J Res and Crit Care Med.
2006
Pharmacologic profiling of transcriptional targets deciphers promoter logic.
Freebern, W.J., Haggerty, C.M., Montano, I., McNutt, M.C., Collins, I., Graham, A., Chandramouli, G.V.R., Stewart, D.H., Biebuyck, H.A., Taub, D.D., Gardner, K.
Pharmacogenomics J.
2005
A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease.
Björkqvist, M., Wild, E.J., Thiele, J., Silvestroni, A., Andre, R., Lahiri, N., Raibon, E., Lee, R.V., Benn, C.L., Soulet, D., Magnusson, A., Woodman, B., Landles, C., Pouladi, M.A., Hayden, M.R., Khalili-Shirazi, A., Lowdell, M.W., Brundin, P., Bates, G.P., Leavitt, B.R., Möller, T., Tabrizi, S.J.
J Exp Med.
2008
Insulin resistance is associated with a metabolic profile of altered protein metabolism in Chinese and Asian-Indian men.
Tai, E.S., Tan, M.L., Stevens, R.D., Low, Y.L., Muehlbauer, M.J., Goh, D.L., Ilkayeva, O.R., Wenner, B.R., Bain, J.R., Lee, J.J., Lim, S.C., Khoo, C.M., Shah, S.H., Newgard, C.B.
Diabetologia
2010
Mycophenolic Acid Differentially Impacts B Cell Function Depending on the Stage of Differentiation.
Karnell, J.L., Karnell, F.G. 3rd, Stephens, G.L., Rajan, B., Morehouse, C., Li, Y., Swerdlow, B., Wilson, M., Goldbach-Mansky, R., Groves, C., Coyle, A.J., Herbst, R., Ettinger, R.
J Immunol Methods
2011
A Small Molecule That Mimics the BB-loop in the Toll Interleukin-1 (IL-1) Receptor Domain of MyD88 Attenuates Staphylococcal Enterotoxin B-induced Pro-inflammatory Cytokine Production and Toxicity in Mice.
Kissner, T.L., Moisan, L., Mann, E., Alam, S., Ruthel, G., Ulrich, R.G., Rebek, M., Rebek, J. Jr, Saikh, K.U.
J Biol Chem.
2011
Assessing immune function by profiling cytokine release from stimulated blood leukocytes and the risk of infection in rheumatoid arthritis.
Krause, M.L., Davis, J.M. 3rd, Knutson, K.L., Strausbach, M.A., Crowson, C.S., Therneau, T.M., Wettstein, P.J., Matteson, E.L., Gabriel, S.E.
Clin Immunol.
2011
Variance in the Acute Inflammatory Response to Prolonged Cycling Is Linked to Exercise Intensity.
Nieman, D.C., Konrad, M., Henson, D.A., Kennerly, K., Shanely, R.A., Wallner-Liebmann, S.J.
J Interferon Cytokine Res.
2011
Tenascin-C induces inflammatory mediators and matrix degradation in osteoarthritic cartilage.
Patel, L., Sun, W., Glasson, S.S., Morris, E.A., Flannery, C.R., Chockalingam, P.S.
BMC Musculoskelet Disord.
2011
Acute Exacerbations of COPD: Identification of Biological Clusters and Their Biomarkers.
Bafadhel, M., McKenna, S., Terry, S., Mistry, V., Reid, C., Haldar, P., McCormick, M., Haldar, K., Kebadze, T., Duvoix, A., Lindblad, K., Patel, H., Rugman, P., Dodson, P., Jenkins, M., Saunders, M., Newbold, P., Green, R.H., Venge, P., Lomas, D.A., Barer, M.R., Johnston, S.L., Pavord, I.D., Brightling, C.E.
Am J Respir Crit Care Med.
2011
Higher Levels of CRP, D-dimer, IL-6, and Hyaluronic Acid Before Initiation of Antiretroviral Therapy (ART) Are Associated With Increased Risk of AIDS or Death.
Boulware, D.R., Hullsiek, K.H., Puronen, C.E., Rupert, A., Baker, J.V., French, M.A., Bohjanen, P.R., Novak, R.M., Neaton, J.D., Sereti, I; for the INSIGHT Study Group.
J Infect Dis.
2011
Serum protein profiling of systemic lupus erythematosus and systemic sclerosis using recombinant antibody microarrays.
Carlsson, A., Wuttge, D.M., Ingvarsson, J., Bengtsson, A.A., Sturfelt, G., Borrebaeck, C.A., Wingren, C.
Mol Cell Proteomics.
2011
Maturation of human dendritic cells with Saccharomyces cerevisiae (yeast) reduces the number and function of regulatory T cells and enhances the ratio of antigen-specific effectors to regulatory T cells.
Cereda, V., Vergati, M., Huen, N.Y., di Bari, M.G., Jochems, C., Intrivici, C., Gulley, J.L., Apelian, D., Schlom, J., Tsang, K.Y.
Vaccine.
2011
Presurgical stress management improves postoperative immune function in men with prostate cancer undergoing radical prostatectomy.
Cohen, L., Parker, P.A., Vence, L., Savary, C., Kentor, D., Pettaway, C., Babaian, R., Pisters, L., Miles, B., Wei, Q., Wiltz, L., Patel, T., Radvanyi, L.
Psychosom Med.
2011
A signature of aberrant immune responsiveness identifies myocardial dysfunction in rheumatoid arthritis.
Davis, J.M. 3rd, Knutson, K.L., Strausbauch, M.A., Crowson, C.S., Therneau, T.M., Wettstein, P.J., Roger, V.L., Matteson, E.L., Gabriel, S.E.
Arthritis Rheum.
2011
Characterization Of Specific Antibodies Against Cytomegalovirus-Encoded IL-10 Produced By 28% Of The CMV-Seropositive Blood Donors.
de Lemos Rieper, C., Galle, P., Pedersen, B.K., Hansen, M.B.
J Gen Virol.
2011
Eosinophil and neutrophil extracellular DNA traps in human allergic asthmatic airways.
Dworski, R., Simon, H.U., Hoskins, A., Yousefi, S.
J Allergy Clin Immunol.
2011
The Antagonists But Not Partial Agonists of Glucocorticoid Receptor Ligands Show Substantial Side Effect Dissociation.
Hu, X., Du, S., Tunca, C., Braden, T., Long, K.R., Lee, J., Webb, E.G., Dietz, J.D., Hummert, S., Rouw, S., Hegde, S.G., Webber, R.K., Obukowicz, M.G.
Endocrinology
2011
The NKT cell ligand agalactosylceramide suppresses allergic airway inflammation by induction of a Th1 response.
Knothe, S., Mutschler, V., Rochlitzera, S., Winkler, C., Ebensen, T., Guzman, C.A., Hohlfeld, J., Braun, A., Muller, M.
Vaccine.
2011
A role for reactive oxygen species in endotoxin-induced elevation of MOR expression in the nervous and immune systems.
Langsdorf, E.F., Mao, X., Chang, S.L.
J Neuroimmunol.
2011
Association of detectable cytomegalovirus (CMV) DNA in monocytes rather than positive CMV IgG serology with elevated neopterin levels in community-dwelling older adults.
Leng, S.X., Li, H., Xue, Q.L., Tian, J., Yang, X., Ferrucci, L., Fedarko, N., Fried, L.P., Semba, R.D.
Exp Gerontol.
2011
Cyst fluid interleukin-1beta (IL1beta) levels predict the risk of carcinoma in intraductal papillary mucinous neoplasms of the pancreas.
Maker, A.V., Katabi, N., Qin, L.X., Klimstra, D.S., Schattner, M., Brennan, M.F., Jarnagin, W.R., Allen, P.J.
Clin Cancer Res.
2011
Placental Growth Factor and Soluble c-Kit Receptor Dynamics Characterize the Cytokine Signature of Imatinib in Prostate Cancer and Bone Metastases.
Mathew, P., Wen, S., Morita, S., Thall, P.F.
J Interferon Cytokine Res.
2011
Markers of endothelial dysfunction, coagulation and tissue fibrosis independently predict venous thromboembolism in HIV.
Musselwhite, L.W., Sheikh, V., Norton, T.D., Rupert, A., Porter, B.O., Penzak, S.R., Skinner, J., Mican, J.M., Hadigan, C., Sereti, I.
AIDS
2011
Blockade of Toll-like receptor 2 prevents spontaneous cytokine release from rheumatoid arthritis ex vivo synovial explant cultures.
Nic An Ultaigh, S., Saber, T.P., McCormick, J., Connolly, M., Dellacasagrande, J., Keogh, B., McCormack, W., Reilly, M., O'Neill, L.A., McGuirk, P., Fearon, U., Veale, D.J.
Arthritis Res Ther.
2011
Tobacco smoke exposure and altered nasal responses to live attenuated influenza virus.
Noah, T.L., Zhou, H., Monaco, J., Horvath, K., Herbst, M., Jaspers, I.
Environ Health Perspect.
2011
IL-10 Blocks Phagosome Maturation in Mycobacterium tuberculosis-infected Human Macrophages.
O'Leary, S., O'Sullivan, M.P., Keane, J.
Am J Respir Cell Mol Biol.
2011
Microparticles (ectosomes) shed by stored human platelets downregulate macrophages and modify the development of dendritic cells.
Sadallah, S., Eken, C., Martin, P.J., Schifferli, J.A.
J Immunol Methods
2011
Differential effects of HIV viral load and CD4 counts on proliferation of naive and memory CD4 and CD8 T lymphocytes.
Srinivasula, S., Lempicki, R.A., Adelsberger, J.W., Huang, C.Y., Roark, J., Lee, P.I., Rupert, A., Stevens, R., Sereti, I., Lane, H.C., Di Mascio, M., Kovacs, J.A.
Blood
2011
Patterns of Th1/Th2 Cytokines Predict Clinical Response in Multiple Sclerosis Patients Treated with Glatiramer Acetate.
Tumani, H., Kassubek, J., Hijazi, M., Lehmensiek, V., Unrath, A., Sussmuth, S., Lauda, F., Kapfer, T., Fang, L., Senel, M., Brettschneider, J.
Eur Neurol.
2011
High-dose zidovudine plus valganciclovir for Kaposi sarcoma herpesvirus-associated multicentric Castleman disease: a pilot study of virus-activated cytotoxic therapy.
Uldrick, T.S., Polizzotto, M.N., Aleman, K., O'Mahony, D., Wyvill, K.M., Wang, V., Marshall, V., Pittaluga, S., Steinberg, S.M., Tosato, G., Whitby, D., Little, R.F., Yarchoan, R.
Blood
2011
Lipopolysaccharide Regulation of Toll-Like Receptor-4 and Matrix Metalloprotease-9 in Human Primary Corneal Fibroblast Cells.
Wong, Y., Sethu, C., Louafi, F., Hossain, P.
Invest Ophthalmol Vis Sci.
2011
The biochemical response to biomechanical tissue loading on the low back during physical work exposure.
Yang, G., Marras, W.S., Best, T.M.
Clin Biomech (Bristol, Avon).
2011
Hepatitis C virions subvert natural killer cell activation to generate a cytokine environment permissive for infection.
Crotta, S., Brazzoli, M., Piccioli, D., Valiante, N.M., Wack, A.
J Hepatol.
2010
Omega-3 fatty acid supplementation improves vascular function and reduces inflammation in obese adolescents.
Dangardt, F., Osika, W., Chen, Y., Nilsson, U., Gan, L.M., Gronowitz, E., Strandvik, B., Friberg, P.
Atherosclerosis.
2010
Analysis of complex biomarkers for human immune-mediated disorders based on cytokine responsiveness of peripheral blood cells.
Davis, J.M. 3rd, Knutson, K.L., Strausbauch, M.A., Crowson, C.S., Therneau, T.M., Wettstein, P.J., Matteson, E.L., Gabriel, S.E.
J Immunol Methods
2010
Macrophage-colony stimulating factor and interleukin-34 induce chemokines in human whole blood.
Eda, H., Zhang, J., Keith, R.H., Michener, M., Beidler, D.R., Monahan, J.B.
Cytokine
2010
Traditional risk factors and D-dimer predict incident cardiovascular disease events in chronic HIV infection.
Ford, E.S., Greenwald, J.H., Richterman, A.G., Rupert, A., Dutcher, L., Badralmaa, Y., Natarajan, V., Rehm, C., Hadigan, C., Sereti, I.
AIDS
2010
Assessing agonistic potential of a candidate therapeutic anti-IL21R antibody.
Guo, Y., Hill, A.A., Ramsey, R.C., Immermann, F.W., Corcoran, C., Young, D., Lavallie, E.R., Ryan, M., Bouchard, T., Pfeifer, R., Warner, G., Bologna, M., Bloom, L., O'Toole, M.
J Transl Med.
2010
Enhancement of Mast Cell IL-6 Production by Combined Toll-Like and Nucleotide-Binding Oligomerization Domain-Like Receptor Activation.
Haidl, I.D., McAlpine, S.M., Marshall, J.S.
Int Arch Allergy Immunol.
2010
Exercise-induced release of cytokines in patients with major depressive disorder.
Hallberg, L., Janelidze, S., Engstrom, G., Wisen, A.G., Westrin, A., Brundin, L.
J Affect Disord.
2010
Cytokine levels in the blood may distinguish suicide attempters from depressed patients.
Janelidze, S., Mattei, D., Westrin, S., Träskman-Bendz, L., Brundin, L.
Brain Behavior and Immunity
2010
No effect of supplementation with cholecalciferol on cytokines and markers of inflammation in overweight and obese subjects.
Jorde, R., Sneve, M., Torjesen, P.A., Figenschau, Y., Gøransson, L.G., Omdal, R.
Cytokine
2010
Substitution of the Bordetella pertussis lipid A phosphate groups with glucosamine is required for robust NF-kappaB activation and release of proinflammatory cytokines in cells expressing human but not murine Toll-like receptor 4-MD-2-CD14.
Marr, N., Hajjar, A.M., Shah, N.R., Novikov, A., Yam, C.S., Caroff, M., Fernandez, R.C.
Infect Immun.
2010
Transcriptional responses in the adaptation to ischaemia-reperfusion injury: a study of the effect of ischaemic preconditioning in total knee arthroplasty patients.
Murphy, T., Walsh, P.M., Doran, P.P., Mulhall, K.J.
J Transl Med.
2010
Effects of exercise combined with caloric restriction on inflammatory cytokines.
Reed, J.L., De Souza, M.J., Williams, N.I.
Appl Physiol Nutr Metab.
2010
Differential IL-17 production and mannan recognition contribute to fungal pathogenicity and commensalism.
Rizzetto, L., Kuka, M., De Filippo, C., Cambi, A., Netea, M.G., Beltrame, L., Napolitani, G., Torcia, M.G., D'Oro, U., Cavalieri, D.
J Immunol Methods
2010
Short-term IL-1beta blockade reduces monocyte CD11b integrin expression in an IL-8 dependent fashion in patients with type 1 diabetes.
Sanda, S., Bollyky, J., Standifer, N., Nepom, G., Hamerman, J.A., Greenbaum, C.
Clin Immunol.
2010
Elevated levels of inflammatory cytokines predict survival in idiopathic and familial pulmonary arterial hypertension.
Soon, E., Holmes, A.M., Treacy, C.M., Doughty, N.J., Southgate, L., Machado, R.D., Trembath, R.C., Jennings, S., Barker, L., Nicklin, P., Walker, C., Budd, D.C., Pepke-Zaba, J., Morrell, N.W.
Circulation.
2010
Transient expression of an IL-23R extracellular domain Fc fusion protein in CHO vs. HEK cells results in improved plasma exposure.
Suen, K.F., Turner, M.S., Gao, F., Liu, B., Althage, A., Slavin, A., Ou, W., Zuo, E., Eckart, M., Ogawa, T., Yamada, M., Tuntland, T., Harris, J.L., Trauger, J.W.
Protein Expr Purif
2010
Natural innate cytokine response to immunomodulators and adjuvants in human precision-cut lung slices.
Switalla, S., Lauenstein, L., Prenzler, F., Knothe, S., Forster, C., Fieguth, H.G., Pfennig, O., Schaumann, F., Martin, C., Guzman, C.A., Ebensen, T., Muller, M., Hohlfeld, J.M., Krug, N., Braun, A., Sewald, K.
Toxicol Appl Pharmacol.
2010
Minocycline attenuates HIV infection and reactivation by suppressing cellular activation in human CD4+ T cells.
Szeto, G.L., Brice, A.K., Yang, H.C., Barber, S.A., Siliciano, R.F., Clements, J.E.
J Infect Dis.
2010
Transforming growth factor beta is a major regulator of human neonatal immune responses following respiratory syncytial virus infection.
Thornburg, N.J., Shepherd, B., Crowe, J.E. Jr.
J Virol.
2010
Response of Th17 cells to a citrullinated arthritogenic aggrecan peptide in patients with rheumatoid arthritis.
von Delwig, A., Locke, J., Robinson, J.H., Ng, W.F.
Arthritis Rheum.
2010
Lymphotoxin-aß heterotrimers are cleaved by metalloproteinases and contribute to synovitis in rheumatoid arthritis.
Young, J., Yu, X., Wolslegel, K., Nguyen, A., Kung, C., Chiang, E., Kolumam, G., Wei, N., Wong, W.L., DeForge, L., Townsend, M.J., Grogan, J.L.
Cytokine
2010
CD44 costimulation promotes FoxP3+ regulatory T cell persistence and function via production of IL-2, IL-10, and TGF-beta.
Bollyky, P.L., Falk, B.A., Long, S.A., Preisinger, A., Braun, K.R., Wu, R.P., Evanko, S.P., Buckner, J.H., Wight, T.N., Nepom, G.T.
J Immunol Methods
2009
A phase I pharmacokinetic and biological correlative study of IMP321, a novel MHC class II agonist, in patients with advanced renal cell carcinoma.
Brignone, C., Escudier, B., Grygar, C., Marcu, M., Triebel, F.
Clin Cancer Res.
2009
Amphipathic DNA polymers exhibit antiviral activity against systemic murine Cytomegalovirus infection.
Cardin, R.D., Bravo, F.J., Sewell, A.P., Cummins, J., Flamand, L., Juteau, J.M., Bernstein, D.I., Vaillant, A.
Virol J.
2009
Validation and comparison of two multiplex technologies, Luminex® and Mesoscale Discovery, for human cytokine profiling.
Chowdhury. F., Williams, A., Johnson, P.
J Immunol Methods
2009
Longitudinal cytokine expression during IMRT for prostate cancer and acute treatment toxicity.
Christensen, E., Pintilie, M., Evans, K.R., Lenarduzzi, M., Menard, C., Catton, C.N., Diamandis, E.P., Bristow, R.G.
Clin Cancer Res.
2009
Indoleamine 2,3-dioxygenase-expressing mature human monocyte-derived dendritic cells expand potent autologous regulatory T cells.
Chung, D.J., Rossi, M., Romano, E., Ghith, J., Yuan, J., Munn, D.H., Young, J.W.
Blood
2009
Targeting gut T cell Ca2+ release-activated Ca2+ channels inhibits T cell cytokine production and T-box transcription factor T-bet in inflammatory bowel disease.
Di Sabatino, A., Rovedatti, L., Kaur, R., Spencer, J.P., Brown, J.T., Morisset, V.D., Biancheri, P., Leakey, N.A., Wilde, J.I., Scott, L., Corazza, G.R., Lee, K., Sengupta, N., Knowles, C.H., Gunthorpe, M.J., McLean, P.G., MacDonald, T.T., Kruidenier, L.
J Immunol Methods
2009
Serum concentrations of cytokines and lung cancer survival in African Americans and Caucasians.
Enewold, L., Mechanic, L.E., Bowman, E.D., Zheng, Y.L., Yu, Z., Trivers, G., Alberg, A.J., Harris, C.C.
Cancer Epidemiol Biomarkers Prev.
2009
Plasma cytokine profiles in systemic sclerosis: associations with autoantibody subsets and clinical manifestations.
Gourh, P., Arnett, F.C., Assassi, S., Tan, F.K., Huang, M., Diekman, L., Mayes, M.D., Reveille, J.D., Agarwal, S.K.
Arthritis Res Ther.
2009
Dexamethasone-pDMAEMA polymeric conjugates reduce inflammatory biomarkers in human intestinal epithelial monolayers.
Keely, S., Ryan, S.M., Haddleton, D.M., Limer, A., Mantovani, G., Murphy, E.P., Colgan, S.P., Brayden, D.J. (
J Control Release.
2009
Circulating and gut-resident human Th17 cells express CD161 and promote intestinal inflammation.
Kleinschek, M.A., Boniface, K., Sadekova, S., Grein, J., Murphy, E.E., Turner, S.P., Raskin, L., Desai, B., Faubion, W.A., de Waal Malefyt, R., Pierce, R.H., McClanahan, T., Kastelein, R.A.
J Exp Med.
2009
Physical training after percutaneous coronary intervention in patients with stable angina: effects on working capacity, metabolism, and markers of inflammation.
Astengo, M., Dahl, A., Karlsson, T., Mattsson-Hultén, L., Wiklund, O., Wennerblom, B.
European Journal of Cardiovascular Prevention & Rehabilitation.
2009
High sensitivity cytokine detection in acute coronary syndrome reveals up-regulation of Interferon Gamma and Interleukin-10 post Myocardial Infarction.
Patel, K.D., Duggan, S.P., Currid, C.A., Gallagher, W.M., McManus, R., Kelleher, D., Murphy, R.T., Ryan, A.W.
Clinical Immunology.
2009
Microbial translocation, the innate cytokine response, and HIV-1 disease progression in Africa.
Redd, A.D., Dabitao, D., Bream, J.H., Charvat, B., Laeyendecker, O., Kiwanuka, N., Lutalo, T., Kigozi, G., Tobian, A.A., Gamiel, J., Neal, J.D., Oliver, A.E., Margolick, J.B., Sewankambo, N., Reynolds, S.J., Wawer, M.J., Serwadda, D., Gray, R.H., Quinn, T.C.
Proc Natl Acad Sci USA.
2009
Human dendritic cell maturation and activation by a heat-killed recombinant yeast (Saccharomyces cerevisiae) vector encoding carcinoembryonic antigen.
Remondo, C., Cereda, V., Mostbock, S., Sabzevari, H., Franzusoff, A., Schlom, J., Tsang, K.Y.
Vaccine.
2009
IL-13 expression by blood T cells and not eosinophils is increased in asthma compared to non-asthmatic eosinophilic bronchitis.
Siddiqui, S., Cruse, G., McKenna, S., Monteiro, W., Mistry, V., Wardlaw, A., Brightling, C.
BMC Pulmonary Medicine.
2009
Ligation of TLR9 induced on human IL-10-secreting Tregs by 1alpha,25-dihydroxyvitamin D3 abrogates regulatory function.
Urry, Z., Xystrakis, E., Richards, D.F., McDonald, J., Sattar, Z., Cousins, D.J., Corrigan, C.J., Hickman, E., Brown, Z., Hawrylowicz, C.M.
J Clin Invest.
2009
Immunomodulatory drugs reorganize cytoskeleton by modulating Rho GTPases.
Xu, Y., Li, J., Ferguson, G.D., Mercurio, F., Khambatta, G., Morrison, L. Lopez-Girona, A., Corral, L.G., Webb, D.R., Bennett, B.L., Xie, W.
Blood
2009
Searching immunodominant epitopes prior to epidemic: HLA class II-restricted SARS-CoV spike protein epitopes in unexposed individuals.
Yang, J.B., James, E., Roti, M., Huston, L., Gebe, J.A., Kwok, W.W.
Intrnl Immuno.
2009
IL-4 protein expression and basal activation of Erk in vivo in follicular lymphoma.
Calvo, K.R., Dabir, B., Kovach, A., Devor, C., Bandle, R., Bond, A., Shih, J.H., Jaffe, E.S.
Blood
2008
HIV infection-associated immune activation occurs by two distinct pathways that differentially affect CD4 and CD8 T cells.
Catalfamo, M., Di Mascio, M., Hu, Z., Srinivasula, S., Thaker, V., Adelsberger, J., Rupert, A., Baseler, M., Tagaya, Y., Roby, G., Rehm, C., Follmann, D., Lane, H.C.
PNAS.
2008
Lactoferrin acts as an alarmin to promote the recruitment and activation of APCs and antigen-specific immune responses.
de la Rosa, G., Yang, D., Tewary, P., Varadhachary, A., Oppenheim, J.J.
J Immunol Methods
2008
Novel structurally related compounds reactivate latent HIV-1 in a bcl-2-transduced primary CD4+ T cell model without inducing global T cell activation.
Xing S, Bhat S, Shroff NS, Zhang H, Lopez JA, Margolick JB, Liu JO, Siliciano RF.
J Antimicrob Chemother.
2012
Serum and Colonic Mucosal Immune Markers in Irritable Bowel Syndrome.
Chang L, Adeyemo M, Karagiannidis I, Videlock EJ, Bowe C, Shih W, Presson AP, Yuan PQ, Cortina G, Gong H, Singh S, Licudine A, Mayer M, Tache Y, Pothoulakis C, Mayer EA.
Am J Gastroenterol.
2012
Qualitative Differences in T cell responses to Live, Attenuated and Inactivated Influenza Vaccines.
Eichelberger MC, Rivers KH, Ream R, Gao J, Hassantoufighi A, Straight TM.
J Clin Cell Immunol.
2011
Upregulation of IL-17, but not of IL-9, in circulating cells of CIS and relapsing MS patients. Impact of corticosteroid therapy on the cytokine network.
Muls N, Jnaoui K, Dang HA, Wauters A, Van Snick J, Sindic CJ, van Pesch V.
J Neuroimmunol.
2012
Profiling of sputum inflammatory mediators in asthma and chronic obstructive pulmonary disease.
Bafadhel M, McCormick M, Saha S, McKenna S, Shelley M, Hargadon B, Mistry V, Reid C, Parker D, Dodson P, Jenkins M, Lloyd A, Rugman P, Newbold P, Brightling CE.
Respiration.
2012
A profile of immune response to herpesvirus is associated with radiographic joint damage in rheumatoid arthritis.
Davis JM 3rd, Knutson KL, Skinner JA, Strausbauch MA, Crowson CS, Therneau TM, Wettstein PJ, Matteson EL, Gabriel SE.
Arthritis Res Ther.
2012
Cycling to work in London and inhaled dose of black carbon.
Nwokoro C, Ewin C, Harrison C, Ibrahim M, Dundas I, Dickson I, Mushtaq N, Grigg J.
Eur Respir J.
2012
Langerhans cells from human cutaneous squamous cell carcinoma induce strong type 1 immunity.
Fujita H, Suárez-Fariñas M, Mitsui H, Gonzalez J, Bluth MJ, Zhang S, Felsen D, Krueger JG, Carucci JA.
J Invest Dermatol.
2012
CRACM/Orai ion channel expression and function in human lung mast cells.
Ashmole I, Duffy SM, Leyland ML, Morrison VS, Begg M, Bradding P.
J Allergy Clin Immunol.
2012
Macrophages are related to goblet cell hyperplasia and induce MUC5B but not MUC5AC in human bronchus epithelial cells.
Silva MA, Bercik P.
Lab Invest.
2012
The role of TRKA signaling in IL-10 production by apoptotic tumor cell-activated macrophages.
Ley S, Weigert A, Weichand B, Henke N, Mille-Baker B, Janssen RA, Brüne B.
Oncogene.
2012
Natural-source d-α-tocopheryl acetate inhibits oxidant stress and modulates atopic asthma in humans in vivo.
Hoskins A, Roberts JL 2nd, Milne G, Choi L, Dworski R.
Allergy.
2012
Examining the positive effects of exercise in intubated adults in ICU: A prospective repeated measures clinical study.
Winkelman C, Johnson KD, Hejal R, Gordon NH, Rowbottom J, Daly J, Peereboom K, Levine AD.
Intensive Crit Care Nurs.
2012
Bananas as an Energy Source during Exercise: A Metabolomics Approach.
Nieman, DC, Gillitt, ND, Henson, DA, Sha, W, Shanely, RA, Knab, AM, Cialdella-Kam, L, Jin, F.
PLoS One.
2012
Human mesenchymal stem cells protect human islets from pro-inflammatory cytokines.
Yeung TY, Seeberger KL, Kin T, Adesida A, Jomha N, Shapiro AM, Korbutt GS.
PLoS One
2012
Prostaglandin E2: a putative potency indicator of the immunosuppressive activity of human mesenchymal stem cells.
Solchaga, LA, Zale, EA.
Am J Stem Cell
2012
Plasma neopterin level as a marker of peripheral immune activation in amnestic mild cognitive impairment and Alzheimer's disease.
Parker DC, Mielke MM, Yu Q, Rosenberg PB, Jain A, Lyketsos CG, Fedarko NS, Oh ES.
Int J Geriatr Psychiatry.
2012
Efficiency of log wood combustion affects the toxicological and chemical properties of emission particles.
Tapanainen M, Jalava PI, Mäki-Paakkanen J, Hakulinen P, Lamberg H, Ruusunen J, Tissari J, Jokiniemi J, Hirvonen MR.
Inhal Toxicol.
2012
Synthetic double-stranded RNA induces innate immune responses similar to a live viral vaccine in humans.
Caskey M, Lefebvre F, Filali-Mouhim A, Cameron MJ, Goulet JP, Haddad EK, Breton G, Trumpfheller C, Pollak S, Shimeliovich I, Duque-Alarcon A, Pan L, Nelkenbaum A, Salazar AM, Schlesinger SJ, Steinman RM, Sékaly RP.
J Exp Med.
2011
Phase II Study of Bevacizumab in Patients With HIV-Associated Kaposi's Sarcoma Receiving Antiretroviral Therapy.
Uldrick TS, Wyvill KM, Kumar P, O'Mahony D, Bernstein W, Aleman K, Polizzotto MN, Steinberg SM, Pittaluga S, Marshall V, Whitby D, Little RF, Yarchoan R.
J Clin Oncol.
2012
Sarcoidosis and Tuberculosis Cytokine Profiles: Indistinguishable in Bronchoalveolar Lavage but Different in Blood.
Thillai M, Eberhardt C, Lewin AM, Potiphar L, Hingley-Wilson S, Sridhar S, Macintyre J, Kon OM, Wickremasinghe M, Wells A, Weeks ME, Mitchell D, Lalvani A.
PLoS One
2012
Ways of coping and biomarkers of an increased atherothrombotic cardiovascular disease risk in elderly individuals.
von Kanel R, Mausbach BT, Dimsdale JE, Mills PJ, Patterson TL, Ancoli-Israel S, Ziegler MG, Roepke SK, Allison M, Grant I.
Cardiovascular Psychiatry and Neurology
2012
Optimisation of grass pollen nasal allergen challenge for assessment of clinical and immunological outcomes.
Scadding GW, Calderon MA, Bellido V, Koed GK, Nielsen NC, Lund K, Togias A, Phippard D, Turka LA, Hansel TT, Durham SR, Wurtzen PA.
J Immunol Methods.
2012
Comparison of Multiplex Immunoassay Platforms.
Fu, Q., Zhu, J., Van Eyk, J.E.
Clinical Chemistry.
2010
Therapeutic Inhibition of Pro-Inflammatory Signaling and Toxicity to Staphylococcal Enterotoxin B by a Synthetic Dimeric BB-Loop Mimetic of MyD88.
Kissner TL, Ruthel G, Alam S, Mann E, Ajami D, Rebek M, Larkin E, Fernandez S, Ulrich RG, Ping S, Waugh DS, Rebek J Jr, Saikh KU.
PLoS One.
2012
The release of IL-31 and IL-13 after nasal allergen challenge and their relation to nasal symptoms.
Baumann R, Rabaszowski M, Stenin I, Gaertner-Akerboom M, Scheckenbach K, Wiltfang J, Schipper J, Wagenmann M.
Clin Transl Allergy.
2012
A key role for the endothelium in NOD1 mediated vascular inflammation: comparison to TLR4 responses.
Gatheral T, Reed DM, Moreno L, Gough PJ, Votta BJ, Sehon CA, Rickard DJ, Bertin J, Lim E, Nicholson AG, Mitchell JA.
PLoS One.
2012
Arachidonate 15-Lipoxygenase Type B Knockdown Leads to Reduced Lipid Accumulation and Inflammation in Atherosclerosis.
Magnusson, LU, Lundqvist A, Karlsson MN, Skalen K, Levin M, Wiklund O, Boren J, Hulten LM.
PLoS One
2012
Helicobacter pylori induces in vivo expansion of human regulatory T cells through stimulating IL-1β-production by dendritic cells
Mitchell PJ, Afzali B, Fazekasova H, Chen D, Ali N, Powell N, Lord GM, Lechler RI, Lombardi G.
Clinical & Experimental Immunology
2012
Chia seed supplementation and disease risk factors in overweight women: a metabolomics investigation.
Nieman DC, Gillitt N, Jin F, Henson DA, Kennerly K, Shanely RA, Ore B, Su M, Schwartz S.
J Altern Complement Med.
2012
Interrelationship of depression, stress and inflammation in cancer patients: A preliminary study.
Archer JA, Hutchison IL, Dorudi S, Stansfeld SA, Korszun A.
J Affect Disord.
2012
Phase I clinical trial of mixed bacterial vaccine (Coley's toxins) in patients with NY-ESO-1 expressing cancers: Immunological effects and clinical activity.
Karbach J, Neumann A, Brand K, Wahle C, Siegel E, Maeurer M, Ritter E, Tsuji T, Gnjatic S, Old LJ, Ritter G, Jäger E.
Clin Cancer Res.
2012
Changes in novel biomarkers of disease activity in juvenile and adult dermatomyositis are sensitive biomarkers of disease course.
Reed AM, Peterson E, Bilgic H, Ytterberg SR, Amin S, Hein MS, Crowson CS, Ernste F, Gillespie EB.
Arthritis Rheum.
2012
Changes in serum and cerebrospinal fluid cytokines in response to non-neurological surgery: an observational study.
Bromander S, Anckarsäter R, Kristiansson M, Blennow K, Zetterberg H, Anckarsäter H, Wass CE.
J Neuroinflammation.
2012
Influence of red pepper spice and turmeric on inflammation and oxidative stress biomarkers in overweight females: A metabolomics approach.
Nieman DC, Cialdella-Kam L, Knab AM, Shanely RA.
Plant Foods Hum Nutr.
2012
Monocytes and γδ T cells control the acute phase response to intravenous zoledronate: Insights from a phase IV safety trial.
Welton JL, Morgan MP, Martí S, Stone MD, Moser B, Sewell AK, Turton J, Eberl M.
J Bone Miner Res.
2012
Selective antagonist reveals the role of prostaglandin receptor EP2 in cancer cell proliferation, invasion and inflammation.
Jiang J, Dingledine R.
J Pharmacol Exp Ther.
2012
Use of PD biomarkers to drive dose selection and early clinical decision making.
Robas NM.
Bioanalysis
2012
Differential serum cytokine responses to inactivated and live attenuated seasonal influenza vaccines.
Ramakrishnan A, Althoff KN, Lopez JA, Coles CL, Bream JH.
Cytokine
2012
Experimental pain and opioid analgesia in volunteers at high risk for obstructive sleep apnea
Doufas AG, Tian L, Padrez KA, Suwanprathes P, Cardell JA, Maecker HT, Panousis P.
PLoS One
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Correlation between cytokine levels and changes in fatigue and quality of life in patients with acute myeloid leukemia.
Fung FY, Li M, Breunis H, Timilshina N, Minden MD, Alibhai SM.
Leuk Res.
2013
Glutathione S-transferase P1 Ile105Val polymorphism modulates allergen-induced airway inflammation in human atopic asthmatics in vivo
Hoskins A, Wu P, Reiss S, Dworski R.
Clinical & Experimental Allergy
2013
Blood CD33(+)HLA-DR(-) myeloid-derived suppressor cells are increased with age and a history of cancer.
Verschoor CP, Johnstone J, Millar J, Dorrington MG, Habibagahi M, Lelic A, Loeb M, Bramson JL, Bowdish DM.
J Leukoc Biol
2013
Association of IL-12p70 and IL-6:IL-10 ratio with autism-related behaviors in 22q11.2 deletion syndrome: A preliminary report.
Ross H, Guo Y, Coleman K, Ousley O, Miller A.
Brain Behav Immun
2013
TRIF-mediated TLR3 and TLR4 signaling is negatively regulated by ADAM15.
Ahmed S, Maratha A, Butt AQ, Shevlin E, Miggin SM.
J Immunol
2013
Generation and characterization of fully human monoclonal antibodies against human Orai1 for autoimmune disease.
Lin FF, Elliott R, Colombero A, Gaida K, Kelley L, Moksa A, Ho SY, Bykova E, Wong M, Rathanaswami P, Hu S, Sullivan JK, Nguyen HQ, McBride HJ.
J Pharmacol Exp Ther
2013
Helicobacter pylori-induced disruption of monolayer permeability and proinflammatory cytokine secretion in polarized human gastric epithelial cells.
Fiorentino M, Ding H, Blanchard TG, Czinn SJ, Sztein MB, Fasano A.
Infect Immun
2013
Biomarkers of inflammation and coagulation are associated with mortality and Hepatitis flares in persons coinfected with HIV and Hepatitis viruses.
Andrade BB, Hullsiek KH, Boulware DR, Rupert A, French MA, Ruxrungtham K, Montes ML, Price H, Barreiro P, Audsley J, Sher A, Lewin SR, Sereti I; for the INSIGHT Study Group.
J Infect Dis
2013
Anti-inflammatory cytokines, pro-fibrogenic chemokines and persistence of acute HCV infection.
Osburn WO, Levine JS, Chattergoon MA, Thomas DL, Cox AL.
Journal of Viral Hepatitis
2013
Idiopathic normal-pressure hydrocephalus: Pathophysiology and diagnosis by CSF biomarkers.
Jeppsson A, Zetterberg H, Blennow K, Wikkelso C.
Neurology
2013
The TARC/sICAM5 ratio in patient plasma is a candidate biomarker for drug resistant epilepsy
Pollard JR, Eidelman O, Mueller GP, Dalgard CL, Crino PB, Anderson CT, Brand EJ, Burakgazi E, Ivaturi SK, Pollard HB.
Front Neurol
2012
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