Search For Scientific Publications - Meso Scale Discovery

Research laboratories and drug development companies around the world use MSD technology to analyze disease states through the characterization and quantification of biomarkers. We maintain a list of scientific journal articles that describe how MSD assays have been instrumental in providing highly sensitive, quantified, reproducible results.

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Title	Journal	Year
Mice lacking epithelial I-κB kinase are protected from lipopolysaccharide and cigarette smoke extract induced inflammation. Lamb D, Parker N, Ulrich K, Jones G, Apfeldorfer C, Pasparakis M, Evans S, Kilty I.	J Pulmon Resp Med	2013
Age-dependent neuroplasticity mechanisms in Alzheimer Tg2576 mice following modulation of brain amyloid-β levels Lilja AM, Rojdner J, Mustafiz T, Thome CM, Storelli E, Gonzalez D, Unger-Lithner C, Greig NH, Nordberg A, Marutle A.	PLoS One	2013
Shedding LIGHT (TNFSF14) on the tumor microenvironment of colorectal cancer liver metastases. Qin JZ, Upadhyay V, Prabhakar B, Maker AV.	J Transl Med	2013
The TARC/sICAM5 ratio in patient plasma is a candidate biomarker for drug resistant epilepsy Pollard JR, Eidelman O, Mueller GP, Dalgard CL, Crino PB, Anderson CT, Brand EJ, Burakgazi E, Ivaturi SK, Pollard HB.	Front Neurol	2012
Vital exhaustion and markers of low-grade inflammation in healthy adults: The Amsterdam Growth and Health Longitudinal Study. Hoekstra T, Barbosa-Leiker C, Twisk JW.	Stress Health	2013
Associations of interleukin-6 with vegetative but not affective depressive symptoms in terminally ill cancer patients. Inagaki M, Akechi T, Okuyama T, Sugawara Y, Kinoshita H, Shima Y, Terao K, Mitsunaga S, Ochiai A, Uchitomi Y.	Support Care Cancer	2013
Phase II study of a neutrophil elastase inhibitor (AZD9668) in patients with bronchiectasis. Stockley R, De Soyza A, Gunawardena K, Perrett J, Forsman-Semb K, Entwistle N, Snell N.	Respir Med	2013
Tetrathiomolybdate-associated copper depletion decreases circulating endothelial progenitor cells in women with breast cancer at high risk of relapse. Jain S, Cohen J, Ward MM, Kornhauser N, Chuang E, Cigler T, Moore A, Donovan D, Lam C, Cobham MV, Schneider S, Hurtado Rúa SM, Benkert S, Mathijsen Greenwood C, Zelkowitz R, Warren JD, Lane ME, Mittal V, Rafii S, Vahdat LT.	Ann Oncol	2013
C-reactive protein predicts the long-term progression of interstitial lung disease and survival in patients with early systemic sclerosis. Liu X, Mayes MD, Phd CP, Draeger HT, Gonzalez EB, Harper BE, Reveille JD, Assassi S.	Arthritis Care Res	2013
Anti-inflammatory cytokines, pro-fibrogenic chemokines and persistence of acute HCV infection. Osburn WO, Levine JS, Chattergoon MA, Thomas DL, Cox AL.	Journal of Viral Hepatitis	2013
Immune enhancing properties of the novel Matrix-M™ adjuvant leads to potentiated immune responses to an influenza vaccine in mice. Magnusson SE, Reimer JM, Karlsson KH, Lilja L, Bengtsson KL, Stertman L.	Vaccine	2013
Biomarkers of inflammation and coagulation are associated with mortality and Hepatitis flares in persons coinfected with HIV and Hepatitis viruses. Andrade BB, Hullsiek KH, Boulware DR, Rupert A, French MA, Ruxrungtham K, Montes ML, Price H, Barreiro P, Audsley J, Sher A, Lewin SR, Sereti I; for the INSIGHT Study Group.	J Infect Dis	2013
Helicobacter pylori-induced disruption of monolayer permeability and proinflammatory cytokine secretion in polarized human gastric epithelial cells. Fiorentino M, Ding H, Blanchard TG, Czinn SJ, Sztein MB, Fasano A.	Infect Immun	2013
Effect of Linezolid on clinical severity and pulmonary cytokines in a murine model of Influenza A and Staphylococcus aureus coinfection. Liu X, He Y, Xiao K, White JR, Fusco DN, Papanicolaou GA	PLoS One	2013
Abdominal obesity, independent from caloric intake, accounts for the development of intestinal tumors in Apc1638N/+ female mice. Huffman DM, Augenlicht LH, Zhang X, Lofrese JJ, Atzmon G, Chamberland JP, Mantzoros CS.	Cancer Prev Res	2013
Generation and characterization of fully human monoclonal antibodies against human Orai1 for autoimmune disease. Lin FF, Elliott R, Colombero A, Gaida K, Kelley L, Moksa A, Ho SY, Bykova E, Wong M, Rathanaswami P, Hu S, Sullivan JK, Nguyen HQ, McBride HJ.	J Pharmacol Exp Ther	2013
Effects of feminine hygiene products on the vaginal mucosal biome. Fashemi B, Delaney ML, Onderdonk AB, Fichorova RN.	Microbial Ecology in Health and Disease	2013
Deficiency in p38β MAPK Fails to Inhibit Cytokine Production or Protect Neurons against Inflammatory Insult in In Vitro and In Vivo Mouse Models. Xing B, Bachstetter AD, Van Eldik LJ.	PLoS One	2013
Quinine controls body weight gain without affecting food intake in male C57BL6 mice. Cettour-Rose P, Bezençon C, Darimont C, le Coutre J, Damak S.	BMC Physiol	2013
A multi-biomarker score measures rheumatoid arthritis disease activity in the BeSt study. Hirata S, Dirven L, Shen Y, Centola M, Cavet G, Lems WF, Tanaka Y, Huizinga TW, Allaart CF.	Rheumatology (Oxford)	2013
A salmon peptide diet alleviates experimental colitis as compared with fish oil Grimstad T, Bjorndal B, Cacabelos D, Aasprong OG, Omdal R, Svardal A, Bohov P, Pamplona R, Portero-Otin M, Berge RK, Hausken T.	Journal of Nutritional Science	2013
TRIF-mediated TLR3 and TLR4 signaling is negatively regulated by ADAM15. Ahmed S, Maratha A, Butt AQ, Shevlin E, Miggin SM.	J Immunol	2013
A hepcidin lowering agent mobilizes iron for incorporation into red blood cells in an adenine-induced kidney disease model of anemia in rats. Sun CC, Vaja V, Chen S, Theurl I, Stepanek A, Brown DE, Cappellini MD, Weiss G, Hong CC, Lin HY, Babitt JL.	Nephrol Dial Transplant	2013
Association of IL-12p70 and IL-6:IL-10 ratio with autism-related behaviors in 22q11.2 deletion syndrome: A preliminary report. Ross H, Guo Y, Coleman K, Ousley O, Miller A.	Brain Behav Immun	2013
Blood CD33(+)HLA-DR(-) myeloid-derived suppressor cells are increased with age and a history of cancer. Verschoor CP, Johnstone J, Millar J, Dorrington MG, Habibagahi M, Lelic A, Loeb M, Bramson JL, Bowdish DM.	J Leukoc Biol	2013

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