Search For Scientific Publications - Meso Scale Discovery

Research laboratories and drug development companies around the world use MSD technology to analyze disease states through the characterization and quantification of biomarkers. We maintain a list of scientific journal articles that describe how MSD assays have been instrumental in providing highly sensitive, quantified, reproducible results.

Enter keywords to search all publications. To see a complete list of publications by research topic, select an area of interest.

Title	Journal	Year
NEW! Assessment of DBS technology for the detection of therapeutic antibodies. Prince PJ, Matsuda KC, Retter M, Scott G.	Bioanalysis. 2010 Aug;2(8):1449-60.	2010
Discovery of diverse and functional antibodies from large human repertoire antibody libraries. Schwimmer LJ, Huang B, Giang H, Cotter RL, Chemla-Vogel DS, Dy FV, Tam EM, Zhang F, Toy P, Bohmann DJ, Watson SR, Beaber JW, Reddy N, Kuan HF, Bedinger DH, Rondon IJ.	J Immunol Methods	2013
Use of primary human cells in high-throughput screens. Dunne A, Jowett M, Rees S.	Methods Mol Biol	2009
An automated immunoassay for early specificity profiling of antibodies. Frese K, Eisenmann M, Ostendorp R, Brocks B, Pabst S.	MAbs	2013
High throughput solution-based measurement of antibody-antigen affinity and epitope binning. Estep P, Reid F, Nauman C, Liu Y, Sun T, Sun J, Xu Y.	mAbs	2013
Use of PD biomarkers to drive dose selection and early clinical decision making. Robas NM.	Bioanalysis	2012
Correlation of screening and confirmatory results in tiered immunogenicity testing by solution-phase bridging assays Kubiak RJ, Zhang L, Zhang J, Zhu Y, Lee N, Weichold FF, Yand H, Abraham V, Akufongwe PF, Hewitt L, Robinson S, Liu W, Liu X, Patnaik MM, Spitz S, Wu Y, Roskos LK.	Journal of Pharmaceutical and Biomedical Analysis	2012
Overcoming soluble target interference in an anti-therapeutic antibody screening assay for an antibody-drug conjugate therapeutic. Carrasco-Triguero M, Mahood C, Milojic-Blair M, Amaya C, Ruppel J, Hong K, Yi JH, Kaur S.	Bioanalysis.	2012
Development and evaluation of a multiplex enzyme-linked immunosorbent assay for the detection of antibodies to bovine respiratory diseases on the Meso Scale Discovery platform. Mayers J, Sawyer J.	J Vet Diagn Invest.	2012
Lateral Clustering of TLR3:dsRNA Signaling Units Revealed by TLR3ecd:3Fabs Quaternary Structure. Luo J, Obmolova G, Malia TJ, Wu SJ, Duffy KE, Marion JD, Bell JK, Ge P, Zhou ZH, Teplyakov A, Zhao Y, Lamb RJ, Jordan JL, San Mateo LR, Sweet RW, Gilliland GL.	J Mol Biol.	2012
Challenges in multi-plex and mono-plex platforms for the discovery of inflammatory profiles in neurodegenerative diseases. Malekzadeh A, de Groot V, Beckerman H, van Oosten BW, Blankenstein MA, Teunissen C.	Methods.	2012
Development of electrochemiluminescence-based singleplex and multiplex assays for the quantification of α-synuclein and other proteins in cerebrospinal fluid. Kruse N, Schulz-Schaeffer WJ, Schlossmacher MG, Mollenhauer B.	Methods.	2012
Probing the solution structure of tumor necrosis factor-α homotrimer and heterotrimer after complex perturbation using electrospray ionization mass spectrometry. Beil EJ, Heavner GA, Wu SJ, Nemeth JF.	J Mol Recognit.	2012
Characterization of a high-affinity human antibody with a disulfide bridge in the third complementarity-determining region of the heavy chain. Almagro JC, Raghunathan G, Beil E, Janecki DJ, Chen Q, Dinh T, Lacombe A, Connor J, Ware M, Kim PH, Swanson RV, Fransson J.	J Mol Recognit.	2012
A novel, high-sensitivity and drug-tolerant sandwich immunoassay for the quantitative measurement of circulating proteins. Sloan JH, Ackermann BL, Carpenter JW, Nguyen HT, Stopa K, Siegel RW, Konrad RJ.	Bioanalysis.	2012
Critical Appraisal of Four IL-6 Immunoassays. Thompson, DK, Huffman, KM, Kraus, WE, Kraus, VB.	PLoS One.	2012
Autophagy-dependent regulation of the DNA damage response protein ribonucleotide reductase 1. Dyavaiah, M., Rooney, J.P., Chittur, S.V., Lin, Q., Begley, T.J.	Mol Cancer Res.	2011
Comparison of a New Multiplex Binding Assay versus the Enzyme-Linked Immunosorbent Assay for Measurement of Serotype-Specific Pneumococcal Capsular Polysaccharide IgG. Goldblatt, D., Ashton, L., Zhang, Y., Antonello, J., Marchese, R.D.	Clin Vaccine Immunol.	2011
Impact of matrix-associated soluble factors on the specificity of the immunogenicity assessment. Bautista, A.C., Wullner, D., Moxness, M., Swanson, S.J., Chirmule, N., Jawa, V.	Bioanalysis	2010
A novel gamma-fitting statistical method for anti-drug antibody assays to establish assay cut points for data with non-normal distribution. Schlain, B., Amaravadi, L., Donley, J., Wickramasekera, A., Bennett, D., Subramanyam, M.	Journal of Immunological Methods	2010
Rheumatoid factor interference in immunogenicity assays for human monoclonal antibody therapeutics. Tatarewicz, S., Miller, J.M., Swanson, S.J., Moxness, M.S.	Journal of Immunological Methods	2010
Identification and inhibition of drug target interference in immunogenicity assays. Zhong, Z.D., Dinnogen, S., Hokom, M., Ray, C., Weinreich, D., Swanson, S.J., Chirmule, N.	Journal of Immunological Methods	2010
A bioactive drug quantitation based approach for the detection of anti-drug neutralizing antibodies in human serum. Hu, J., Gupta, S., Swanson, S.J., Zhuang, Y.	Journal of Immunological Methods	2009
Technology comparisons for anti-therapeutic antibody and neutralizing antibody assays in the context of an anti-TNF pharmacokinetic study. Loyet, K.M., Deng, R., Liang, W.C., Wu, Y., Lowman, H.B., Deforge, L.E.	Journal of Immunological Methods	2009
Application of multi-factorial design of experiments to successfully optimize immunoassays for robust measurements of therapeutic proteins. Ray, C.A., Patel, V., Shih, J., Macaraeg, C., Wu, Y., Thway, T., Ma, M., Lee, J.W., Desilva, B.	Journal of Pharmaceutical and Biomedical Analysis	2009

Page 1 of 3

Next > Last >|