ECL Diagram Electrochemiluminescence detection uses labels that emit light when electrochemically stimulated. Background signals are minimal because the stimulation mechanism (electricity) is decoupled from the signal (light). Labels are stable, non-radioactive and offer a choice of convenient coupling chemistries. They emit light at ~620 nm, eliminating problems with color quenching. Few compounds interfere with electrochemiluminescent labels so you can use large, diverse libraries with confidence. Multiple excitation cycles of each label amplify the signal to enhance light levels and improve sensitivity.