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Toxicity determination for drug candidates is an area that increasingly requires measurements of several protein biomarkers. The best biomarkers are specific to particular organs or tissue types. Researchers require an assay system with consistent performance, high sensitivity, and large dynamic range. MSD provides all of these characteristics plus multiplexing to save time and precious sample.
MSD Toxicology Assay Kits are qualified through a rigorous procedure that includes multi-plate, multi-day studies to ensure suitability for use in toxicology testing. Result reported in the Product Inserts include:
- Sensitivity
- Precision
- Spike Recovery
- Dilution Linearity
- Sample Study of Normal and Treated Samples
Qualification Studies of our Toxicology Panel Assays are available in our literature section.
MSD Toxicology Assays are available as singleplex and panel assays in 96-well format.
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Product Inserts and Data are in PDF format. |
Qualified Panel Assay
| Description |
Analytes |
Lot Numbers |
Availability |
| Argutus AKI Test® (rat) |
aGST, GSTYb1, RPA-1 |
K0040052
K0040055
|
insert
insert
insert |
| Kidney Injury Panel 1 (rat) |
Albumin, TIM-1, Lipocalin-2, Osteopontin |
K0040049
K0040054
|
insert
insert
insert |
| Cardiac Injury Panel 2 (rat) |
cTnI, cTnT, FABP3 |
|
insert |
| Cardiac Injury Panel 3 (rat) |
cTnI, cTnT, FABP3, Myl3 |
|
insert |
| Muscle Injury Panel 1 (rat) |
cTnI, cTnT, sTnI, FABP3, Myl3 |
K0040050
K0040062
K0040075 |
insert
insert
insert |
| Acute Phase Protein Panel 1 (rat) |
A2M, AGP |
|
insert |
| Steroid Hormone Panel 1 (rat/mouse/human) |
Estradiol, Progesterone, Testosterone, DHEA |
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AKI Test is a registered trademark of Argutus Medical Limited
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