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Toxicity determination for drug candidates is an area that increasingly requires measurements of several protein biomarkers. The best biomarkers are specific to particular organs or tissue types. Researchers require an assay system with consistent performance, high sensitivity, and large dynamic range. MSD provides all of these characteristics plus multiplexing to save time and precious sample.
MSD Toxicology Assay Kits are validated through a rigorous procedure that includes multi-plate, multi-day studies to ensure suitability for use in toxicology testing. Result reported in the Product Inserts include:
- Sensitivity
- Precision
- Spike Recovery
- Dilution Linearity
- Sample Study of Normal and Treated Samples
Validation Studies of our Toxicology Panel Assays are available in our literature section.
MSD Toxicology Assays are available as singleplex and panel assays in 96-well format.
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Product Inserts and Data are in PDF format. |
Multiplex Panels
| Description |
Analytes |
Availability |
Certificate of Analysis |
Lot Numbers |
Data |
Insert |
Argutus AKI Test® (rat) |
aGST, GSTYb1, RPA-1 |
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C of A K0040080 |
K0040080 |
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view |
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K0040055 |
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view |
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K0040052 |
|
view |
| Kidney Injury Panel 1 (rat) |
Albumin, TIM-1, NGAL, Osteopontin |
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C of A K0040156
C of A K0040147
C of A K0040142
C of A K0040121
C of A K0040087
C of A K0040074 |
K0040156
K0040147
K0040142
K0040121
K0040087
K0040074 |
|
view |
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K0040056 |
|
view |
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K0040049 |
|
view |
| Kidney Injury Panel 3 (human) |
aGST, Calbindin, Clusterin, KIM-1, Osteoactivin, TFF3, VEGF |
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C of A K0040136 |
K0040136 |
view |
view |
| Kidney Injury Panel 5 (human) |
Albumin, B2M, Cystatin C, EGF, NGAL, OPN, UMOD |
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C of A K0040164
C of A K0040133 |
K0040133 |
view |
view |
| Cardiac Injury Panel 2 (rat) |
cTnI, cTnT, FABP3 |
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C of A K0040171
C of A K0040100
C of A K0040079
C of A K0040077 |
K0040171 K0040100 K0040079 K0040077 |
|
view |
| Cardiac Injury Panel 3 (rat) |
cTnI, cTnT, FABP3, Myl3 |
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C of A K0040171
C of A K0040100
C of A K0040079
C of A K0040077 |
K0040171 K0040100 K0040079 K0040077 |
|
view |
| Muscle Injury Panel 1 (rat) |
cTnI, cTnT, sTnI, FABP3, Myl3 |
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C of A K0040157
C of A K0040088
C of A K0040083
C of A K0040078 |
K0040157
K0040088
K0040083
K0040078 |
|
view |
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K0040075 |
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view |
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K0040062 |
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view |
| Muscle Injury Panel 2 (rat) |
Parvalbumin, TIMP-1, CK |
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C of A K0040097 |
K0040097 |
view |
view |
| Muscle Injury Panel 3 (mouse) |
cTnI, FABP3, Myl3, sTnI |
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C of A K0040107 |
K0040107 |
view |
view |
Acute Phase Protein Panel 1 (rat) |
A2M, AGP |
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C of A K0040137
C of A K0040093
C of A K0040082 |
K0040137
K0040093
K0040082 |
|
view |
| Inflammation Panel 1 (rat) |
NGAL, TSP-1, TIMP-1, MCP-1 |
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C of A K0040139
C of A K0040127
C of A K0040124
C of A K0040089 |
K0040139
K0040127
K0040124
K0040089 |
view |
view |
| Inflammation Panel 3 (cyno) |
MCP-1, NGAL, TIMP-1 |
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C of A K0040128 |
K0040128 |
view |
view |
| Liver Injury Panel 1 (rat) |
Arginase-1, aGST |
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C of A K0040178
C of A K0040090 |
K0040090 |
view |
view |
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AKI Test is a registered trademark of Argutus Medical Limited
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