Assays and Kits - Meso Scale Discovery

4E-BP1 (pT37/46)
4E-BP1 (total) ‡
Abeta 38
Abeta 40
Abeta 42
Total Abeta
Adiponectin
AFP
Akt (pS473)
Akt (pT308)
Akt (total)
Albumin ‡
ALP
AMPK-a1 (pS485) ‡
AMPK-a1 (pT174/172) ‡
AMPK-a1 (total) ‡
Angiopoietin 1 ‡
Angiopoietin 2 ‡
Apolipoprotein A1 ‡
Apolipoprotein C3 ‡
Aurora A (pT288)
B2M ‡
BAD (pS112)
BAD (total)
BDNF
Calbindin ‡
Calprotectin ‡
cAMP
Cancer Antigen 125
Cancer Antigen 15.3 ‡
Caspase-3 (p20/p17) (cleaved)
Caspase-3 (total)
CEA
Chk1 (pS296) ‡
c-Jun (pS63)
c-Kit (pY721)
c-Kit (total)
CK-MB
Clusterin ‡
C-Peptide
CRP
CTACK ‡
Cystatin C ‡
DHEA
E-Cadherin
EGF ‡
EGFR (pY1068)
EGFR (pY1173)
EGFR (total)
eIF2a (pS51) ‡
eIF4E (pS209) ‡
eIF4E (total) ‡
ENA-78 ‡
Endoglin ‡
Eotaxin
Eotaxin-3
EphB4 (total) ‡
EPO
ErbB2 (pY1248)
ErbB2 (total)
ErbB3 (HER3) (pY) ‡
ERK-1/2 (pT202/pY204),
(pT185/pY187)
ERK-1/2 (total)
ERK-5 (pT218/pY220)
E-Selectin
Estradiol
FasL ‡
FGF (acidic) ‡
FGF (basic)
FOXO3a (pT32)
FRS2 (pY196)
FRS2 (pY436)
FSH
GAPDH ‡
G-CSF
Active Ghrelin ‡
GLP-1 (x-36) amide
Active GLP-1 (7-36) amide
Active GLP-1 (ver. 2)
Total GLP-1 (ver. 2)
Glucagon
GM-CSF
GRO-a
GSK-3a (pS21)
GSK-3a (total) ‡
GSK-3b (pS9)
GSK-3b (total)
HCG ‡
HGF
HIF-1a
Histone H3 (pS10)
HSP27 (pS15)
HSP27 (pS78)
HSP27 (pS82)

HSP27 (total)
HSP70 (total)
IFN-a2a
IFN-b
IFN-g
IGF-1R (pY)
IGF-1R (total)
IGFBP-1
IL-1ra ‡
IL-1a
IL-1b
IL-2
IL-4
IL-5
IL-6
IL-6R
IL-7
IL-8
IL-10
IL-12
IL-12 p40
IL-12 p70
IL-13
IL-15
IL-16
IL-17
IL-18 ‡
IL-23 ‡
Immunoglobulin Isotyping and
Quantification
Insulin
IP-10
IP-10 (urine) ‡
IR (pY)
IR (total)
IRS-1 (pS312)
IRS-1 (total)
I-TAC
JAK2 (pY1007/1008) ‡
JAK2 (total) ‡
JNK (pT183/pY185)
JNK (total)
KDR (sVEGFR2)
LBP
Leptin
Luteinizing Hormone (LH) *
MAPKAPK2 (pT334)
MCP-1
MCP-2 ‡
MCP-3 ‡
MCP-4
M-CSF
MDC
MDM2 - p53 complex
MDM2 (self-ubiquitinated)
(activity assay)
MDM2 (total)
MDM2 (ubiquitinated)
MEK1/2 (pS217/221)
MEK1/2 (total)
MEK2 (total)
Met (pY1349)
Met (total)
MIF ‡
MIG
MIP-1a
MIP-1b
MIP-3a
MIP-3ß ‡
MMP-1
MMP-2
MMP-3
MMP-8 ‡
MMP-9
MMP-10
MPO
mTOR (pS2448)
Myoglobin
NFkB (pS468)
NFkB (pS536)
NFkB (total) ‡
NGAL/Lipocalin-2 ‡
NGAL/Lipocalin-2 (urine) ‡
NT-proBNP
Osteoactivin ‡
Osteocalcin
Osteonectin
Osteopontin
Osteopontin (urine) ‡
Osteoprotegerin
p21 (total) ‡
p38 (pT180/pY182)
p38 (total)
p53 (pS15)
p53 (total)

p53 (ubiquitinated)
p70S6K (pT389)
p70S6K (pT421/pS424)
p70S6K (total)
Total PAI-1 ‡
PARP (D214) (cleaved)
P-Cadherin
PDGFR-b (pY751)
PDH E1a (pS293) ‡
PEDF/Serpin F1 ‡
PlGF
Pleckstrin (pS) ‡
PRAS40 (pT246)
PRAS40 (total)
Progesterone
Prolactin
PSA ‡
P-Selectin
Total PYY ‡
RANTES
Rb (pS608)
Rb (pS780)
Rb (total)
Resistin
RON (pT1238/1239) ‡
S6RP (pS235/236)
S6RP (pS240/244)
S6RP (total)
SAA
sAPPa
sAPPb
sAPPb sw
Sclerostin
SDF-1a ‡
sEGFR
sErbB2
sFas ‡
sFlt-1 (sVEGFR1)
sICAM-1
sICAM-3
Smad1 (pS463/465) ‡
sMet ‡
sRAGE ‡
SRC3 (total) ‡
STAT3 (pY705)
STAT4 (pY693)
STAT4 (total)
STAT5a/b (pY694)
STAT5a/b (total)
sVCAM-1
T3 ‡
T4 ‡
TARC
Tau (pS202)
Tau (pS262) ‡
Tau (pS396) ‡
Tau (pT181)
Tau (pT231)
Tau (total)
TFF3 ‡
TGF-b1
TGF-b2 ‡
TGF-b3 ‡
Thrombomodulin
Tie-2 ‡
TIMP-1 *
TIMP-1 (urine) ‡
TIMP-2 ‡
TNF-RI
TNF-RII
TNF-a
TNF-b ‡
TRAIL ‡
Troponin I (cTnI)
Troponin T (cTnT)
TSH ‡
TSLP ‡
Tuberin (pT1462) ‡
TWEAK ‡
uPA ‡
Uromodulin ‡
VASP (pS157)
VASP (pS239)
VASP (total)
VEGF(121/165)
VEGF (urine) ‡
VEGF-C ‡
VEGF-D ‡
VEGFR-2 (pY1054)
VEGFR-2 (total)
aGST ‡
b-NGF ‡
b-Secretase (activity assay)
pGST ‡

4E-BP1 (pT37/46)
4E-BP1 (total) ‡
Abeta 38
Abeta 40
Abeta 42
Adiponectin
Akt (pS473)
Akt (pT308)
Akt (total)
cAMP
c-Jun (pS63)
eIF2a (pS51) ‡
EPO
ERK-1/2 (pT202/pY204),
(pT185/pY187)
ERK-1/2 (total)
Estradiol
FOXO3a (pT32)
FRS2 (pY196)
FRS2 (pY436)
Ghrelin
GLP-1 (x-36) amide
Active GLP-1 (7-36) amide
Active GLP-1 (ver. 2)
Total GLP-1 (ver. 2)
Glucagon
GM-CSF
GSK-3b (pS9)
GSK-3b (total)
HIF-1a
Histone H3 (pS10)
IFN-g

IL-1b
IL-2
IL-4
IL-5
IL-6
IL-10
IL-12
IL-12 p40
IL-12 p70
IL-13
IL-17
IL-23 ‡
Immunoglobulin Isotyping and
Quantification
Insulin
Isotyping Panel 1
(IgGA, IgG1, IgG2a, IgG2b, IgG3, IgM)
JNK (pT183/pY185)
KC/GRO/CINC (CXCL1)
Leptin
MAPKAPK2 (pT334)
MCP-1
M-CSF ‡
MDM2 (ubiquitinated)
MEK1/2 (pS217/221)
MEK1/2 (total)
MEK2 (total)
MIP-1a ‡
MIP-1b ‡
MIP-2 ‡
MIP-3a ‡
MMP-9 ‡

p38 (pT180/pY182)
p38 (total)
p53 (total)
p53 (ubiquitinated)
p70S6K (pT389)
p70S6K (pT421/pS424)
p70S6K (total)
PDGFR-b (pY751)
PRAS40 (pT246)
Total PAI-1 ‡
Total PYY ‡
RANTES
Resistin
S6RP (pS235/236)
S6RP (pS240/244)
S6RP (total)
sAPPb
sRAGE ‡
STAT3 (pY705)
STAT5a/b (pY694)
STAT5a/b (total)
T3 ‡
T4 ‡
Tau (pT231)
Tau (total)
TNF-RI
TNF-RII
TNF-a
VEGF(121/165)
VEGFR-2 (pY1175)

A2M *
Abeta 38
Abeta 40
Abeta 42
Adiponectin
AGP *
Akt (pS473)
Akt (total)
Albumin *
Arginase-1
B2M *
BNP
cAMP
Cardiac Troponin I *
Cardiac Troponin T *
CINC-2 ‡
CINC-3 ‡
c-Jun (pS63)
Clusterin *
CNTF-1 ‡
C-Peptide
eIF2a (pS51) ‡
EPO
ERK-1/2 (pT202/pY204),
(pT185/pY187)
ERK-1/2 (total)
Estradiol
FABP3 *
FOXO3a (pT32)
Ghrelin
GLP-1 (x-36) amide
Active GLP-1 (7-36) amide

Active GLP-1 (ver. 2)
Total GLP-1 (ver. 2)
Glucagon
GM-CSF
GSK-3b (pS9)
GSK-3b (total)
GSTYb1 *
HIF-1a
Histone H3 (pS10)
IFN-g
IL-1a
IL-1b
IL-2 ‡
IL-4
IL-5
IL-6
IL-10 ‡
IL-13
Insulin
JNK (pT183/pY185)
KC/GRO/CINC (CXCL1)
Leptin
Lipocalin-2 *
L-Selectin ‡
MCP-1
MDM2 (ubiquitinated)
MEK1/2 (pS217/221)
MEK1/2 (total)
MEK2 (total)
MIP-3a
Myl3 *
NT-proBNP

Osteopontin *
p38 (pT180/pY182)
p38 (total)
p53 (total)
p53 (ubiquitinated)
p70S6K (pT389)
p70S6K (pT421/pS424)
p70S6K (total)
PRAS40 (pT246)
Total PYY ‡
Resistin
RPA-1 *
S6RP (pS235/236)
S6RP (pS240/244)
S6RP (total)
sAPPb
sICAM-1 ‡
Skeletal Troponin I *
sRAGE ‡
STAT3 (pY705)
T3 ‡
T4 ‡
TIM-1/KIM-1/HAVCR *
TIMP-1 ‡
TNF-a
TNNI1 ‡
Troponin ITC Complex
TSP-1
VEGF(121/165)
aGST

Active GLP-1 (ver. 2)
Total GLP-1 (ver. 2)
GM-CSF ‡
IFN-g ‡
IL-2
IL-6
IL-8
IL-10
MCP-1 ‡
TNF-a

4E-BP1 (pT37/46)
4E-BP1 (total) ‡
Akt (pS473)
Akt (pT308)
Akt (total)
AMPK-a1 (pS485) ‡
AMPK-a1 (pT174/172) ‡
AMPK-a1 (total) ‡
Aurora A (pT288)
BAD (pS112)
BAD (total)
Chk1 (pS296) ‡
c-Jun (pS63)
c-Kit (pY721)
c-Kit (total)
Caspase-3 (p20/p17) (cleaved)
Caspase-3 (total)
EGFR (pY1068)
EGFR (pY1173)
EGFR (total)
eIF2a (pS51) ‡
eIF4E (pS209) ‡
eIF4E (total) ‡
EphB4 (total) ‡
ErbB2 (pY1248)
ErbB2 (total)
ErbB3 (HER3) (pY) ‡
ERK-1/2 (pT202/pY204),
(pT185/pY187)
ERK-1/2 (total)
ERK-5 (pT218/pY220)
FOXO3a (pT32)
FRS2 (pY196)
FRS2 (pY436)
GAPDH ‡
GSK-3a (pS21)

GSK-3a (total) ‡
GSK-3b (pS9)
GSK-3b (total)
HIF-1a (total)
Histone H3 (pS10)
HSP27 (pS15)
HSP27 (pS78)
HSP27 (pS82)
HSP27 (total)
HSP70 (total)
IGF-1R (pY)
IGF-1R (total)
IR (pY)
IR (total)
IRS-1 (pS312)
IRS-1 (total)
JAK2 (pY1007/1008) ‡
JAK2 (total) ‡
JNK (pT183/pY185)
JNK (total)
MAPKAPK2 (pT334)
MEK1/2 (pS217/221)
MEK1/2 (total)
MEK2 (total)
Met (pY1349)
Met (total)
mTOR (pS2448)
NFkB (pS468)
NFkB (pS536)
NFkB (total) ‡
p21 (total) ‡
p38 (pT180/pY182)
p38 (total)
p53 (pS15)
p53 (total)
p70S6K (pT389)

p70S6K (pT421/pS424)
p70S6K (total)
PARP (D214) (cleaved)
PDGFR-b (pY751)
PDH E1a (pS293) ‡
Pleckstrin (pS) ‡
PRAS40 (pT246)
PRAS40 (total)
Rb (pS608)
Rb (pS780)
Rb (total)
RON (pT1238/1239) ‡
S6RP (pS235/236)
S6RP (pS240/244)
S6RP (total)
Smad1(pS463/465) ‡
SRC3 (Total) ‡
STAT3 (pY705)
STAT4 (pY693)
STAT4 (total)
STAT5a/b (pY694)
STAT5a/b (total)
Tau (pS202)
Tau (pS262) ‡
Tau (pS396) ‡
Tau (pT181)
Tau (pT231)
Tau (total)
Tuberin (pT1462) ‡
VASP (pS157)
VASP (pS239)
VASP (total)
VEGFR-2 (pY1054)
VEGFR-2 (pY1175)
VEGFR-2 (total)

CHO Host Cell Protein
Insulin
Methotrexate (MTX)
Protein A

cAMP
Cell-Based Antibody Screening
Immunogenicity
Immunoglobulin Isotyping and Quantification
Intact (Whole) Antibodies (human)
Isotyping Panel 1 (mouse) (IgGA, IgG1, IgG2a, IgG2b, IgG3, IgM)
Neutralization Assays
Pharmacokinetic Assays for Protein Therapeutics