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Phospho(Ser473)/Total Akt Base Kit

Product Detail
Application Phosphoproteins & Intracellular Markers
Analyte Akt
Species Human, Mouse, Rat
Instrument SI2400, SI6000
Plate Type 96-well multiplex
 
Documents
Title Lot Number
doc Product insert
doc Data sheet
Product Options
Catalog No. Product Name Size
Additional Information
Related Publications Journal Year  
GDC-0980 is a novel class I PI3K/mTOR kinase inhibitor with robust activity in cancer models driven by the PI3K pathway.
Wallin, J.J., Edgar, K.A., Guan, J., Berry, M., Prior, W.W., Lee, L., Lesnick, J.D., Lewis, C., Nonomiya, J., Pang, J., Salphati, L., Olivero, A.G., Sutherlin, D.P., O'Brien, C., Spoerke, J.M., Patel, S., Lensun, L., Kassees, R., Ross, L., Lackner, M.R., Sampath, D., Belvin, M., Friedman, L.S.
Mol Cancer Ther. 2011
Osteopontin Is Required for the Early Onset of High Fat Diet-Induced Insulin Resistance in Mice.
Chapman, J., Miles, P.D., Ofrecio, J.M., Neels, J.G., Yu, J.G., Resnik, J.L., Wilkes, J., Talukdar, S., Thapar, D., Johnson, K., Sears, D.D.
PLoS ONE 2010
Tumor necrosis factor-alpha regulates inflammatory and mesenchymal responses via mitogen-activated protein kinase kinase, p38, and nuclear factor kappaB in human endometriotic epithelial cells.
Grund, E.M., Kagan, D., Tran, C.A., Zeitvogel, A., Starzinski-Powitz, A., Nataraja, S., Palmer, S.S.
Mol Pharmacol. 2008
Development of sulfonamide AKT PH domain inhibitors.
Ahad, A.M., Zuohe, S., Du-Cuny, L., Moses, S.A., Zhou, L.L., Zhang, S., Powis, G., Meuillet, E.J., Mash, E.A.
Bioorg Med Chem Lett 2011
Efficacy of Ganitumab (AMG 479), Alone and in Combination With Rapamycin, in Ewing's and Osteogenic Sarcoma Models.
Beltran, P.J., Chung, Y.A., Moody, G., Mitchell, P., Cajulis, E., Vonderfecht, S., Kendall, R., Radinsky, R., Calzone, F.J.
Pharmacol Exp Ther. 2011

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Price and Availability
Price Please call for price
Size 20 plates
Catalog No. K15100A-3
Availability Usually ships in 1-3 days

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