Search For Scientific Publications - Meso Scale Discovery

Research laboratories and drug development companies around the world use MSD technology to analyze disease states through the characterization and quantification of biomarkers. We maintain a list of scientific journal articles that describe how MSD assays have been instrumental in providing highly sensitive, quantified, reproducible results.

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Title	Journal	Year
Susceptibility of adult and senescent Brown Norway rats to repeated ozone exposure: an assessment of behavior, serum biochemistry and cardiopulmonary function. Gordon CJ, Jarema KA, Lehmann JR, Ledbetter AD, Schladweiler MC, Schmid JE, Ward WO, Kodavanti UP, Nyska A, MacPhail RC.	Inhal Toxicol	2013
Assessment of cisplatin-induced kidney injury using an integrated rodent platform. Chen Y, Brott D, Luo W, Gangl E, Kamendi H, Barthlow H, Lengel D, Fikes J, Kinter L, Valentin JP, Bialecki R.	Toxicol Appl Pharmacol	2013
Irreversible renal damage after transient Renin-Angiotensin System stimulation: involvement of an AT1-receptor mediated immune response. Heijnen BF, Nelissen J, van Essen H, Fazzi GE, Cohen Tervaert JW, Peutz-Kootstra CJ, Mullins JJ, Schalkwijk CG, Janssen BJ, Struijker-Boudier HA.	PLoS One	2013
Detection of Botulinum Neurotoxin Serotypes A and B using a chemiluminescent versus electrochemiluminescent immunoassay in food and serum. Cheng LW, Stanker LH.	J Agric Food Chem	2013
Bacillus anthracis protective antigen kinetics in inhalation spore-challenged untreated or Levofloxacin/ Raxibacumab-treated New Zealand White rabbits. Corey A, Migone TS, Bolmer S, Fiscella M, Ward C, Chen C, Meister G.	Toxins	2013
Immunosorbent analysis of ricin contamination in milk using colorimetric, chemiluminescent and electrochemiluminescent detection. Brandon DL, Korn AM, Yang LL.	Food and Agricultural Immunology	2013
Underestimation of urinary biomarker-to-creatinine ratio resulting from age-related gain in muscle mass in rats. Tonomura Y, Morikawa Y, Takagi S, Torii M, Matsubara M.	Toxicology	2012
Renal biomarker changes associated with hyaline droplet nephropathy in rats are time and potentially compound dependent. Brott DA, Bentley P, Nadella MV, Thurman D, Fikes J, Cheatham L, McGrath F, Luo W, Kinter LB.	Toxicology	2012
Botulinum neurotoxin serotype A specific cell-based potency assay to replace the mouse bioassay Fernandez-Salas E, Wang J, Molina Y, Nelson JB, Jacky BPS, Aoki KR.	PLoS One	2012
Evaluation of miR-122 and other biomarkers in distinct acute liver injury in rats Starckx S, Batheja A, Verheyen GR, Jonghe SD, Steemans K, Dijck BV, Singer M, Bogdan N, Snoeys J, Vinken P, Sasaki JC, Gompel JV, Guzzie-Peck P, Lampo A, Lammens L.	Toxicol Pathol.	2012
Kidney injury biomarkers in hypertensive, diabetic, and nephropathy rat models treated with contrast media. Rouse RL, Stewart SR, Thompson KL, Zhang J.	Toxicol Pathol.	2012
Biomarker panel of cardiac and skeletal muscle troponins, fatty acid binding protein 3 and myosin light chain 3 for the accurate diagnosis of cardiotoxicity and musculoskeletal toxicity in rats. Tonomura Y, Matsushima S, Kashiwagi E, Fujisawa K, Takagi S, Nishimura Y, Fukushima R, Torii M, Matsubara M.	Toxicology.	2012
Comparison of urinary and serum levels of di-22:6-bis(monoacylglycerol)phosphate as noninvasive biomarkers of phospholipidosis in rats. Thompson KL, Zhang J, Stewart S, Rosenzweig BA, Shea K, Mans D, Colatsky T.	Toxicol Lett.	2012
Fast and sensitive detection of Bacillus anthracis spores by immunoassay. Morel N, Volland H, Dano J, Lamourette P, Sylvestre P, Mock M, Créminon C.	Appl Environ Microbiol.	2012
Evaluation of novel renal biomarkers with a cisplatin model of kidney injury: gender and dosage differences. Pinches M, Betts C, Bickerton S, Burdett L, Thomas H, Derbyshire N, Jones HB, Moores M.	Toxicol Pathol.	2012
Detection of ricin contamination in liquid egg by electrochemiluminescence immunosorbent assay. Brandon DL, Korn AM, Yang LL.	J Food Sci.	2012
Urine Biomarkers Predict Acute Kidney Injury in Newborns. Askenazi DJ, Koralkar R, Hundley HE, Montesanti A, Parwar P, Sonjara S, Ambalavanan N.	J Pediatr.	2012
Evaluation of novel urinary renal biomarkers: biological variation and reference change values. Pinches MD, Betts CJ, Bickerton SJ, Beattie L, Burdett LD, Thomas HT, Derbyshire NA, Moores M, Price SA.	Toxicol Pathol.	2012
Acute phase response, inflammation and metabolic syndrome biomarkers of Libby asbestos exposure. Shannahan JH, Alzate O, Winnik WM, Andrews D, Schladweiler MC, Ghio AJ, Gavett SH, Kodavanti UP.	Toxicol Appl Pharmacol.	2012
Comparison of the Diagnostic Accuracy of Di-22:6-Bis(monoacylglycerol)Phosphate and Other Urinary Phospholipids for Drug-Induced Phospholipidosis or Tissue Injury in the Rat. Thompson KL, Haskins K, Rosenzweig BA, Stewart S, Zhang J, Peters D, Knapton A, Rouse R, Mans D, Colatsky T.	Int J Toxicol.	2012
Surface Sampling of a Dry Aerosol Deposited Ricin. Edmonds JM, Collett PJ, Brown RL, Mangaya K.	Appl Sci.	2012
(2011) Nephrotoxicity of hexachloro-1:3-butadiene in the male Hanover Wistar rat; correlation of minimal histopathological changes with biomarkers of renal injury. Swain, A., Turton, J., Scudamore, C., Maguire, D., Pereira, I., Freitas, S., Smyth, R., Munday, M., Stamp, C., Gandhi, M., Sondh, S., Ashall, H., Francis, I., Woodfine, J., Bowles, J., York, M.	J Appl Toxicol.	2011
Chronic Antagonism of the Mineralocorticoid Receptor Ameliorates Hypertension and End Organ Damage in a Rodent Model of Salt-Sensitive Hypertension. Zhou, X., Crook, M.F., Sharif-Rodriguez, W., Zhu, Y., Ruben, Z., Pan, Y., Urosevic-Price, O., Wang, L., Flattery, A.M., Forrest, G., Szeto, D., Zhao, H., Roy, S., Forrest, M.J.	Clin Exp Hypertens.	2011
Comparison of the course of biomarker changes and kidney injury in a rat model of drug-induced acute kidney injury. Sasaki, D., Yamada, A., Umeno, H., Kurihara, H., Nakatsuji, S., Fujihira, S., Tsubota, K., Ono, M., Moriguchi, A., Watanabe, K., Seki, J.	Biomarkers.	2011
Agents associated with lung inflammation induce similar responses in NCI-H292 lung epithelial cells. Newland, N., Richter, A.	Toxicol In Vitro.	2008

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