Search For Scientific Publications - Meso Scale Discovery

Research laboratories and drug development companies around the world use MSD technology to analyze disease states through the characterization and quantification of biomarkers. We maintain a list of scientific journal articles that describe how MSD assays have been instrumental in providing highly sensitive, quantified, reproducible results.

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Title	Journal	Year
Resveratrol protects against atherosclerosis, but does not add to the antiatherogenic effect of atorvastatin, in APOE*3-Leiden.CETP mice. Berbee JF, Wong MC, Wang Y, van der Hoorn JW, Khedoe PP, van Klinken JB, Mol IM, Hiemstra PS, Tsikas D, Romijn JA, Havekes LM, Princen HM, Rensen PC.	J Nutr Biochem	2013
Endoglin requirement for BMP9 signaling in endothelial cells reveals new mechanism of action for selective anti-Endoglin antibodies. Nolan-Stevaux O, Zhong W, Culp S, Shaffer K, Hoover J, Wickramasinghe D, Ruefli-Brasse A.	PLoS One	2012
Transgenic mice with high endogenous omega-3 fatty acids are protected from spinal cord injury. Lim SN, Gladman SJ, Dyall SC, Patel U, Virani N, Kang JX, Priestley JV, Michael-Titus AT.	Neurobiol Dis.	2012
Granulocyte colony stimulating factor exacerbates antineutrophil cytoplasmic antibody vasculitis. Freeley SJ, Coughlan AM, Popat RJ, Dunn-Walters DK, Robson MG.	Ann Rheum Dis.	2012
Association between synovial fluid levels of aggrecan ARGS fragments and radiographic progression in knee osteoarthritis. Larsson S, Englund M, Struglics A, Lohmander LS.	Arthritis Res Ther.	2010
Cartilage and bone markers and inflammatory cytokines are increased in synovial fluid in the acute phase of knee injury (hemarthrosis) - a cross-sectional analysis. Sward P, Frobell R, Englund M, Roos H, Struglics A.	Osteoarthritis Cartilage.	2012
Biomarker panel of cardiac and skeletal muscle troponins, fatty acid binding protein 3 and myosin light chain 3 for the accurate diagnosis of cardiotoxicity and musculoskeletal toxicity in rats. Tonomura Y, Matsushima S, Kashiwagi E, Fujisawa K, Takagi S, Nishimura Y, Fukushima R, Torii M, Matsubara M.	Toxicology.	2012
Protective effects of dietary EPA and DHA on ischemia-reperfusion-induced intestinal stress. Brahmbhatt V, Oliveira M, Briand M, Perrisseau G, Bastic Schmid V, Destaillats F, Pace-Asciak C, Benyacoub J, Bosco N.	J Nutr Biochem.	2012
Architectural and biochemical expressions of mustard gas keratopathy: preclinical indicators and pathogenic mechanisms. McNutt P, Lyman M, Swartz A, Tuznik K, Kniffin D, Whitten K, Milhorn D, Hamilton T.	PLoS One.	2012
A key role for the endothelium in NOD1 mediated vascular inflammation: comparison to TLR4 responses. Gatheral T, Reed DM, Moreno L, Gough PJ, Votta BJ, Sehon CA, Rickard DJ, Bertin J, Lim E, Nicholson AG, Mitchell JA.	PLoS One.	2012
Loss-of-function mutations in TGFB2 cause a syndromic presentation of thoracic aortic aneurysm. Lindsay ME, Schepers D, Bolar NA, Doyle JJ, Gallo E, Fert-Bober J, Kempers MJ, Fishman EK, Chen Y, Myers L, Bjeda D, Oswald G, Elias AF, Levy HP, Anderlid BM, Yang MH, Bongers EM, Timmermans J, Braverman AC, Canham N, Mortier GR, Brunner HG, et al.	Nat Genet.	2012
Genetic Variants in Platelet Factor 4 Modulate Inflammatory and Platelet Activation Biomarkers. Bhatnagar P, Lu X, Evans MK, Laveist TA, Zonderman AB, Carter DL, Arking DE, Fletcher CA.	Circ Cardiovasc Genet.	2012
The effect of local anaesthetics on synoviocytes: a possible indirect mechanism of chondrolysis. Braun HJ, Busfield BT, Kim HJ, Scuderi GJ, Dragoo JL.	Knee Surg Sports Traumatol Arthrosc.	2012
TAP1-deficiency does not alter atherosclerosis development in Apoe-/- mice. Kolbus D, Ljungcrantz I, Söderberg I, Alm R, Björkbacka H, Nilsson J, Fredrikson GN.	PLoS One.	2012
The characterization of fibrocyte-like cells: A novel fibroblastic cell of the placenta. Riddell MR, Winkler-Lowen B, Chakrabarti S, Dunk C, Davidge ST, Guilbert LJ.	Placenta.	2012
Trabecular bone loss after administration of the second-generation antipsychotic risperidone is independent of weight gain. Motyl, K.J., Dick-de-Paula, I., Maloney, A.E., Lotinun, S., Bornstein, S., de Paula, F.J., Baron, R., Houseknecht, K.L., Rosen, C.J.	Bone.	2012
Immune Activation Resulting From NKG2D/Ligand Interaction Promotes Atherosclerosis. Xia, M., Guerra, N., Sukhova, G.K., Yang, K., Miller, C.K., Shi, G.P., Raulet, D.H., Xiong, N.	Circulation.	2011
Pharmacology and placental transfer of a human av integrin monoclonal antibody in rabbits. Martin, P. L., Zhou, Z., Van den Bulck, K., Kwok, D., Powers, G., Jiao, Q., Schantz, A., Treacy, G.	Birth Defects Res B Dev Reprod Toxicol.	2010
Identification and inhibition of drug target interference in immunogenicity assays. Zhong, Z.D., Dinnogen, S., Hokom, M., Ray, C., Weinreich, D., Swanson, S.J., Chirmule, N.	Journal of Immunological Methods	2010
Comparison of the effects of n-3 long chain polyunsaturated fatty acids and fenofibrate on markers of inflammation and vascular function, and on the serum lipoprotein profile in overweight and obese subjects. Bragt, M.C., Mensink, R.P.	Nutr Metab Cardiovasc Dis.	2011
Cerebrospinal fluid inflammatory cytokines and biomarkers of injury severity in acute human spinal cord injury. Kwon, B.K., Stammers, A.M., Belanger, L.M., Bernardo, A., Chan, D., Bishop, C.M., Slobogean, G.P., Zhang, H., Umedaly, H., Giffin, M., Street, J., Boyd, M.C., Paquette, S.J., Fisher, C.G., Dvorak, M.F.	J Neurotrauma.	2010
Transcriptional responses in the adaptation to ischaemia-reperfusion injury: a study of the effect of ischaemic preconditioning in total knee arthroplasty patients. Murphy, T., Walsh, P.M., Doran, P.P., Mulhall, K.J.	J Transl Med.	2010
Circulating Transforming Growth Factor-ß in Marfan Syndrome. Matt, P., Schoenhoff, F., Habashi, J., Holm, T., Van Erp, C., Loch, D., Carlson, O.D., Griswold, B.F., Fu, Q., Backer, J.D., PhD, Loey, B., Huso, D.L., McDonnell, N.B., Van Eyk, J.E., Dietz, H.C.	Journal of American Heart Association.	2009
Electrochemiluminescent immunoassay for rat skeletal troponin I (Tnni2) in serum. Sun, D., Hamlin, D., Butterfield, A., Watson, D.E., Smith, H.W.	J Pharmacol Toxicol Methods.	2009
Novel technologies for the discovery and quantitation of biomarkers of toxicity. Collings, F.B., Vaidya, V.S.	Toxicology.	2008

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