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Clinical Immunology
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Phosphoproteins, Intracellular Signaling, and Apoptosis
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NEW:
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42 Peptide ImmunoassaysThat Can be Multiplexed
NEW:
High Throughput Assays for Biomarkers in 384-well Format
NEW:
Antibody Screening Applications Performed Using Electrochemiluminescence
NEW:
Development of Multiplexed Immunoassay Panels forBiochemical Markers of Bone Development
NEW:
MSD MULTI-SPOT
®
384-Well 4 Spot Format: Higher Content and Throughput with Less Sample
NEW:
Multiplex Immunoassay Panels for Human and Rodent Hypoxia Markers
NEW:
Immunogenicity Applications Using Electrochemiluminescence
NEW:
Development of Biomarker Assays for Obesity, Diabetes,and Metabolic Syndrome
NEW:
Multiplex Panels for Measurement of Vascular Injury Biomarkers
Activation of STAT3 by EGFR Variant III: Tyrosine Residue 1068 is the Primary STAT3 Docking Site on EGFR
Development of Multiplexed Immunoassay Panels for Human Growth Factors and Growth Factor Receptors: bFGF, sFlt-1, PlGF, VEGF, KDR and c-Kit
Simultaneous Detection of Akt and MAPK Signaling Pathway Targets Reveals Reciprocal Regulation of Phospho-Akt(S473) and Phospho- S6RP(S235/236 and S240/244) as a Function of Cell Density
Multiplex Arrays for Measuring Protein Ubiquitylation
Human Cytokine Assay Products from Meso Scale Discovery
Multiplex Assays for Ubiquitous Signal Transduction Cascades: MAPK, Apoptosis and Akt/mTOR
A Suite of Assays to Detect Phosphorylated Receptor Tyrosine Kinases Associated with Neoplasia
Multiplex Detection of Alzheimer’s Disease-related Proteins and Peptides
Cardiac Biomarker Assays
Metabolic Marker Assays: Adiponectin, GLP-1, Insulin, Leptin and Resistin
Vascular Injury Biomarkers: Multiplexed Immunoassays
Ubiquitin System as a Target for High-Throughput Screening
Elucidation of Drug Responses by Profiling Signal Transduction Pathways Using Cytokine and Biomarker Panels
Multiplexed Cardiac Marker Assays: Troponin-I, CKMB, and Myoglobin
Revolutionizing Signal Transduction Assays in Drug Discovery: MSD’s Multiplex Phosphoprotein Assays with Cell Signaling Technology’s Antibodies
High Throughput Assays for Inhibitors of Ubiquitin Carrier (E2) and Ubiquitin Ligase (E3) Proteins
Multiplexed Fertility Marker Assays: LH, FSH and Progesterone
High-Throughput Multiplexed Assays for Biomarkers of Hypoxia: VEGF, IGFBP-1 and Erythropoietin
MAPK Cascade as a Signaling Convergence Point in Cancer Therapy: Simultaneous Detection of Activated p38, ERK and JNK
High Throughput Assays for Mouse Metabolic Markers: Insulin, Leptin and Adiponectin
Natural Product Inhibitors Of Specific E3 Ubiquitin Ligases
Development of a Multiplex Array to Simultaneously Monitor p53 Phosphorylation and the Induction of Apoptosis
High Throughput Assay to Screen for Inhibitors of the Proto-Oncogene Stat3
High-Throughput Multiplexed Assays for Biomarkers of Vascular Injury
Detection of Activated EGFR by the Association of Signaling Proteins: Stat3,Grb2 and Shc
Multiplex Measurements of Cytokines in High Density Formats Using MULTI-ARRAY
®
Technology
Analyzing cross-talk between Ras-Raf-MEK-ERK and PI3K-Akt Signaling Pathways: A highly sensitive multiplex assay for simultaneous determination of Phospho-Erk and Phospho-Akt
In vivo phosphorylation of key apoptotic and cell survival markers: simultaneous detection of phosphoproteins in a highly specific multiplex assay format
MSD
®
Technology: A New Way to Measure Classic Markers of Apoptosis
Multiplex Arrays to Measure phospho-p38, phospho-Akt and phospho-p53
A High-Throughput Replacement for Western Blots: Protein Expression Analysis Using the MSD
®
MULTI-ARRAY
®
Platform
Characterization of Novel Substrates of N-end Rule-Dependent Ubiquitylation Identified through a Proteome-Wide Screen
in vitro
Screen
Discovery Of Skeletrophin A Novel Ubiquitin E3 Ligase Regulator of NF-kappaB From A Genome-wide High Throughput Cell-based Assay
P53-MDM2 System as a Target for High-Throughput Screening
MULTI-SPOT
®
Assays: Detection of Multiple Phosphoproteins in Whole Cell Lysates in a Single Well
Detection of Activated EGFR by the Association of Signaling Proteins: Stat3,Grb2 and Shc
Genome-Wide High Throughput Cell-Based Assay for Activators of NFkB
Genome-Wide screen for Protein: Phosphorylated Protein Interactions using MULTI-ARRAY
®
Technology
Map Kinase Activity Assays on MSD
®
MULTI-ARRAY
®
Platform
MDM2 Self-Ubiquitylation: An Example of a High Throughput Assay for Inhibitors of E3 Ligase Activity
High-Throughput, MULTI-ARRAY
®
Assays to Detect Binding of SH2 Domain Proteins to Phosphoproteins
Ultra-High Throughput Screening Using Multi-Array 1536-Well Plates
Proteome-wide High Throughput Cell Based Assay for Apoptotic Genes
Fast, Sensitive Detection of EGF-Induced Receptor Autophosphorylation in Cell Lysates
A MULTI-ARRAY
®
Technology Based Assay for cAMP
An Integrated Approach to High Throughput, High Content Screening for Regulatory Interactions in Epidermal Growth Factor Receptor Regulation
G-Protein Coupled Receptors: A Fast, Convenient Method to Identify Inhibitors of Ligand Binding and Second Messenger Accumulation
High Throughput Kinase Discovery, Inhibitor Screening and Specificity Analysis using Multi-Array Technology