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Cytokines are the soluble factors that mediate acute and chronic inflammatory responses, and are involved in many physiological events from wound healing to autoimmune disorders. MSD's MULTI-ARRAY® technology enables the detection of inflammatory biomarkers in single and multiplex formats. As the next generation of electrochemiluminescence detection, MSD offers cytokine and chemokine assays that;
- have ultra-low detection limits
- provide up to four logs of linear dynamic range
- use minimal sample volume
- handle complex matrices easily
Our Cytokine and Chemokine kits enable the measurement of native levels of biomarkers in normal and diseased samples without multiple dilutions. The ultimate benefit is an increase in productivity with minimal effort and time providing you with high quality results that you can trust.
- Tissue Culture kits are designed for use with cell culture media
- Ultra-Sensitive kits can be used for cell culture media as well as serum, plasma, and other complex matrixes such as urine, sputum, lavage, etc.
MSD offers a suite of singleplex and multiplex cytokine and chemokine kits for a wide range of species:
- Human Cytokine Assays
- Mouse Cytokine Assays
- Rat Cytokine Assays
- Canine Cytokine Assays
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MSD cytokine assays have benefited numerous researchers and scientists worldwide. Here are a few citations highlighting our cytokine product line.
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Fichorova R.N., Richardson-Harman, N., Alfano, M., Belec, L., Carbonneil, C., Chen, S., Cosentino, L., Curtis, K., Dezzutti, C.S., Donoval, B. Doncel, G.F., Donaghay, M., Grivel, J.C., Guzman, E., Hayes, M., Herold, B, Hillier, S., Lackman-Smith, C., Landay, A., Margolis, L., Mayer, K.H., Pasicznyk, J.M., Pallansch-Cokonis, M., Poli, G., Reichelderfer, P., Roberts, P., Rodriguez, I., Saidi, H., Sassi, R.R., Shattock, R., Cummins, J.E. Jr. (2008) Biological and technical variables affecting immunoassay recovery of cytokines from human serum and simulated vaginal fluid: a multicenter study. Anal Chem. Vol. 80(12): 4741-51. |
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Lembo, A., J, Neri, B., Tolley, J., Barken, D., Carroll, S., Pan, H. (2009) Use of serum biomarkers in a diagnostic test for irritable bowel syndrome. Aliment Pharmacol Ther. Vol. 29(8):834-42. |
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Young, J., Yu, X., Wolslegel, K., Nguyen, A., Kung, C., Chiang, E., Kolumam, G., Wei, N., Wong, W.L., DeForge, L., Townsend, M.J., Grogan, J.L. (2010) Lymphotoxin-aß heterotrimers are cleaved by metalloproteinases and contribute to synovitis in rheumatoid arthritis. Cytokine 2010. |
For a complete list of citations using MSD technology for cytokine measurement, visit the MSD Bibliography page.
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MSD takes great pride in the service we provide to our customers. You can search our catalog system to find what you need and request a quote.
To speak with one of our team members or to place an order:
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Assay development is complex, and we're always here to help. Access to our industry-leading scientific support team is provided complimentary for our customers.
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Cytokine Applications
