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Human MCP-1 384 Tissue Culture Kit
The Human MCP-1 Tissue Culture Kit provides assay-specific components for the quantitative determination of both natural and recombinant human monocyte chemoatatic protein-1 (MCP-1 or CCL2) in tissue culture supernatant.

Product Detail
Application Cytokines & Chemokines
Analyte MCP-1
Species Human
Instrument SI2400
Plate Type 384-well singleplex
Documents
Title Lot Number
doc Product insert
Product Options
Catalog No. Product Name Size
K251AYB-2 Human MCP-1 384 Tissue Culture Kit 5 plates
Additional Information
Related Publications Journal Year  
Abnormal peripheral chemokine profile in Huntington’s disease.
Wild, E., Magnusson, A., Lahiri, N., Krus, U., Orth, M., Tabrizi, S.J., Bjorkqvist, M.
PLoS Curr. 2011
Can emerging biomarkers of myocardial remodelling identify asymptomatic hypertensive patients at risk for diastolic dysfunction and diastolic heart failure?
Collier, P., Watson, C.J., Voon, V., Phelan, D., Jan, A., Mak, G., Martos, R., Baugh, J.A., Ledwidge, M.T., McDonald, K.M.
Eur J Heart Fail. 2011
Blood protein concentrations in the first two postnatal weeks associated with early postnatal blood gas derangements among infants born before the 28th week of gestation. The ELGAN Study.
Leviton, A., Allred, E.N., Kuban, K.C., Dammann, O., Fichorova, R.N., O'Shea, T.M., Paneth, N.; for the ELGAN Study Co-Investigators.
Cytokine. 2011
Persistence after birth of systemic inflammation associated with umbilical cord inflammation.
Leviton, A., Hecht, J.L., Allred, E.N., Yamamoto, H., Fichorova, R.N., Dammann, O.; for the ELGAN Study Investigators.
J Reprod Immunol. 2011
Neonatal Cytokine Profile in the Airway Mucosal Lining Fluid is skewed by Maternal Atopy.
Folsgaard, N.V., Chawes, B.L., Rasmussen, M.A., Bischoff, A.L., Carson, C.G., Stokholm, J., Pedersen, L., Hansel, T.T., Bønnelykke, K., Brix, S., Bisgaard, H.
Am J Respir Crit Care Med. 2011

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Price and Availability
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Size 50 plates
Catalog No. K251AYB-6
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Request a Certificate of Analysis
Related Publications Journal Year  
Abnormal peripheral chemokine profile in Huntington’s disease.
Wild, E., Magnusson, A., Lahiri, N., Krus, U., Orth, M., Tabrizi, S.J., Bjorkqvist, M.
PLoS Curr. 2011
Can emerging biomarkers of myocardial remodelling identify asymptomatic hypertensive patients at risk for diastolic dysfunction and diastolic heart failure?
Collier, P., Watson, C.J., Voon, V., Phelan, D., Jan, A., Mak, G., Martos, R., Baugh, J.A., Ledwidge, M.T., McDonald, K.M.
Eur J Heart Fail. 2011
Blood protein concentrations in the first two postnatal weeks associated with early postnatal blood gas derangements among infants born before the 28th week of gestation. The ELGAN Study.
Leviton, A., Allred, E.N., Kuban, K.C., Dammann, O., Fichorova, R.N., O'Shea, T.M., Paneth, N.; for the ELGAN Study Co-Investigators.
Cytokine. 2011
Persistence after birth of systemic inflammation associated with umbilical cord inflammation.
Leviton, A., Hecht, J.L., Allred, E.N., Yamamoto, H., Fichorova, R.N., Dammann, O.; for the ELGAN Study Investigators.
J Reprod Immunol. 2011
Neonatal Cytokine Profile in the Airway Mucosal Lining Fluid is skewed by Maternal Atopy.
Folsgaard, N.V., Chawes, B.L., Rasmussen, M.A., Bischoff, A.L., Carson, C.G., Stokholm, J., Pedersen, L., Hansel, T.T., Bønnelykke, K., Brix, S., Bisgaard, H.
Am J Respir Crit Care Med. 2011
Systemic responses of preterm newborns with presumed or documented bacteremia.
Leviton, A., O'Shea, M.T., Bednarek, F.J., Allred, E.N., Fichorova, R.N., Dammann, O.; for the ELGAN Study Investigators.
Acta Paediatr. 2011
Biochemical, cellular, and anti-inflammatory properties of a potent, selective, orally bioavailable benzamide inhibitor of Rho kinase activity.
Rajagopalan, L.E., Davies, M.S., Kahn, L.E., Kornmeier, C.M., Shimada, H., Steiner, T.A., Zweifel, B.S., Wendling, J.M., Payne, M.A., Loeffler, R.F., Case, B.L., Norton, M.B., Parikh, M.D., Nemirovskiy, O.V., Mourey, R.J., Masferrer, J.L., Misko, T.P., Kolodziej, S.A.
J Pharmacol Exp Ther. 2010
Rho-kinase mediates lysophosphatidic acid-induced IL-8 and MCP-1 production via p38 and JNK pathways in human endothelial cells.
Shimada, H., Rajagopalan, L.E.
FEBS Lett. 2010
Maternal Microbe-Specific Modulation of Inflammatory Response in Extremely Low-Gestational-Age Newborns
Fichorova, R.N., Onderdonk, A.B., Yamamoto, H., Delaney, M.L., DuBois, A.M., Allred, E., Levition, A; for the ELGAN Study Investigators.
mBio 2011
Assessing immune function by profiling cytokine release from stimulated blood leukocytes and the risk of infection in rheumatoid arthritis.
Krause, M.L., Davis, J.M. 3rd, Knutson, K.L., Strausbach, M.A., Crowson, C.S., Therneau, T.M., Wettstein, P.J., Matteson, E.L., Gabriel, S.E.
Clin Immunol. 2011
Cerebrospinal fluid microglial markers in Alzheimer's disease: elevated chitotriosidase activity but lack of diagnostic utility.
Mattsson, N., Tabatabaei, S., Johansson, P., Hansson, O., Andreasson, U., Månsson, J.E., Johansson, J.O., Olsson, B., Wallin, A., Svensson, J., Blennow, K., Zetterberg, H.
Neuromolecular Med. 2011
High-Throughput Simultaneous Analysis of RNA, Protein, and Lipid Biomarkers in Heterogeneous Tissue Samples.
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Clin Chem. 2011
Acute Exacerbations of COPD: Identification of Biological Clusters and Their Biomarkers.
Bafadhel, M., McKenna, S., Terry, S., Mistry, V., Reid, C., Haldar, P., McCormick, M., Haldar, K., Kebadze, T., Duvoix, A., Lindblad, K., Patel, H., Rugman, P., Dodson, P., Jenkins, M., Saunders, M., Newbold, P., Green, R.H., Venge, P., Lomas, D.A., Barer, M.R., Johnston, S.L., Pavord, I.D., Brightling, C.E.
Am J Respir Crit Care Med. 2011
Higher Levels of CRP, D-dimer, IL-6, and Hyaluronic Acid Before Initiation of Antiretroviral Therapy (ART) Are Associated With Increased Risk of AIDS or Death.
Boulware, D.R., Hullsiek, K.H., Puronen, C.E., Rupert, A., Baker, J.V., French, M.A., Bohjanen, P.R., Novak, R.M., Neaton, J.D., Sereti, I; for the INSIGHT Study Group.
J Infect Dis. 2011
Comparison of the effects of n-3 long chain polyunsaturated fatty acids and fenofibrate on markers of inflammation and vascular function, and on the serum lipoprotein profile in overweight and obese subjects.
Bragt, M.C., Mensink, R.P.
Nutr Metab Cardiovasc Dis. 2011
A signature of aberrant immune responsiveness identifies myocardial dysfunction in rheumatoid arthritis.
Davis, J.M. 3rd, Knutson, K.L., Strausbauch, M.A., Crowson, C.S., Therneau, T.M., Wettstein, P.J., Roger, V.L., Matteson, E.L., Gabriel, S.E.
Arthritis Rheum. 2011
Relationship Between Neonatal Blood Protein Concentrations and Placenta Histologic Characteristics in Extremely Low GA Newborns.
Hecht, J.L., Fichorova, R.N., Tang, V.F., Allred, E.N., McElrath, T.F., Leviton, A; Elgan Study Investigators.
Pediatr Res. 2011
Small molecule inhibitors of FABP4/5 ameliorate dyslipidemia but not insulin resistance in mice with diet-induced obesity.
Lan, H., Cheng, C.C., Kowalski, T.J., Pang, L., Shan, L., Chuang, C.C., Jackson, J., Rojas-Triana, A., Bober, L., Liu, L., Voigt, J., Orth, P., Yang, X., Shipps, G.W. Jr, Hedrick, J.A.
J Lipid Res. 2011
Early postnatal blood concentrations of inflammation-related proteins and microcephaly two years later in infants born before the 28th post-menstrual week.
Leviton, A., Kuban, K.C., Allred, E.N., Fichorova, R.N., O'Shea, T.M., Paneth, N.; for the ELGAN Study Investigators.
Early Hum Dev. 2011
The Relationship between Early Concentrations of 25 Blood Proteins and Cerebral White Matter Injury in Preterm Newborns: The ELGAN Study.
Leviton, A., Kuban, K., O'Shea, T.M., Paneth, N., Fichorova, R., Allred, E.N., Dammann, O.
J Pediatr. 2011
Exchanging Saturated Fatty Acids for (n-6) Polyunsaturated Fatty Acids in a Mixed Meal May Decrease Postprandial Lipemia and Markers of Inflammation and Endothelial Activity in Overweight Men.
Masson, C.J., Mensink, R.P.
J Nutr. 2011
Blood protein profiles of infants born before 28th week differ by pregnancy complication.
McElrath, T.F., Fichorova, R.N., Allred, E.N., Hecht, J.L., Ismail, M.A., Yuan, H., Leviton, A; ELGAN Study Investigators.
Am J Obstet Gynecol. 2011
Markers of endothelial dysfunction, coagulation and tissue fibrosis independently predict venous thromboembolism in HIV.
Musselwhite, L.W., Sheikh, V., Norton, T.D., Rupert, A., Porter, B.O., Penzak, S.R., Skinner, J., Mican, J.M., Hadigan, C., Sereti, I.
AIDS 2011
A Long-Acting Tumor Necrosis Factor a-Binding Protein Demonstrates Activity in Both In Vitro and In Vivo Models of Endometriosis.
Altan, Z.M., Denis, D., Kagan, D., Grund, E.M., Palmer, S.S., Nataraja, S.G.
J Pharmacol. 2010
Analysis of complex biomarkers for human immune-mediated disorders based on cytokine responsiveness of peripheral blood cells.
Davis, J.M. 3rd, Knutson, K.L., Strausbauch, M.A., Crowson, C.S., Therneau, T.M., Wettstein, P.J., Matteson, E.L., Gabriel, S.E.
J Immunol Methods 2010
Lactobacillus rhamnosus GG attenuates interferon-{gamma} and tumor necrosis factor-{alpha}-induced barrier dysfunction and pro-inflammatory signalling.
Donato, K.A., Gareau, M.G., Wang, Y.J., Sherman, P.M.
Microbiology. 2010
Macrophage-colony stimulating factor and interleukin-34 induce chemokines in human whole blood.
Eda, H., Zhang, J., Keith, R.H., Michener, M., Beidler, D.R., Monahan, J.B.
Cytokine 2010
Traditional risk factors and D-dimer predict incident cardiovascular disease events in chronic HIV infection.
Ford, E.S., Greenwald, J.H., Richterman, A.G., Rupert, A., Dutcher, L., Badralmaa, Y., Natarajan, V., Rehm, C., Hadigan, C., Sereti, I.
AIDS 2010
Assessing agonistic potential of a candidate therapeutic anti-IL21R antibody.
Guo, Y., Hill, A.A., Ramsey, R.C., Immermann, F.W., Corcoran, C., Young, D., Lavallie, E.R., Ryan, M., Bouchard, T., Pfeifer, R., Warner, G., Bologna, M., Bloom, L., O'Toole, M.
J Transl Med. 2010
The relationship between neonatal blood protein profiles and placenta histologic characteristics in extremely low gestation age newborns.
Hecht, J.L., Fichorova, R.N., Tang, V.F., Allred, E.N., McElrath, T.F., Leviton, A; for the ELGAN study investigators.
Pediatr Res. 2010
No effect of supplementation with cholecalciferol on cytokines and markers of inflammation in overweight and obese subjects.
Jorde, R., Sneve, M., Torjesen, P.A., Figenschau, Y., Gøransson, L.G., Omdal, R.
Cytokine 2010
Inflammation-related proteins in the blood of extremely low gestational age newborns. The contribution of inflammation to the appearance of developmental regulation.
Leviton, A., Fichorova, R., Yamamoto, Y., Allred, E.N., Dammann, O., Hecht, J., Kuban, K., McElrath, T., O'Shea, T.M., Paneth, N.
Cytokine 2010
Short-term IL-1beta blockade reduces monocyte CD11b integrin expression in an IL-8 dependent fashion in patients with type 1 diabetes.
Sanda, S., Bollyky, J., Standifer, N., Nepom, G., Hamerman, J.A., Greenbaum, C.
Clin Immunol. 2010
Natural innate cytokine response to immunomodulators and adjuvants in human precision-cut lung slices.
Switalla, S., Lauenstein, L., Prenzler, F., Knothe, S., Forster, C., Fieguth, H.G., Pfennig, O., Schaumann, F., Martin, C., Guzman, C.A., Ebensen, T., Muller, M., Hohlfeld, J.M., Krug, N., Braun, A., Sewald, K.
Toxicol Appl Pharmacol. 2010
Effects of glycemic load on metabolic risk markers in subjects at increased risk of developing metabolic syndrome.
Vrolix, R., Mensink, R.P.
Am J Clin Nutr. 2010
A phase I pharmacokinetic and biological correlative study of IMP321, a novel MHC class II agonist, in patients with advanced renal cell carcinoma.
Brignone, C., Escudier, B., Grygar, C., Marcu, M., Triebel, F.
Clin Cancer Res. 2009
An in vitro perfusion system to examine the responses of endothelial cells to simulated flow and inflammatory stimulation.
Cockcroft, N.Y., Oke, O., Cunningham, F., Bishop, E., Fearon, I.M., Zantl, R., Gaca, M.D.
Altern Lab Anim. 2009
Atorvastatin reduces plasma levels of chemokine (CXCL10) in patients with Crohn's disease.
Grip, O., Janciauskiene, S.
PLoS ONE 2009
Increased levels of inflammatory chemokines in amyotrophic lateral sclerosis.
Kuhle, J., Lindberg, R.L., Regeniter, A., Mehling, M., Steck, A.J., Kappos, L, Czaplinski, A.
Eur J of Neurology. 2009
Natural History of Markers of Collagen Turnover in Patients With Early Diastolic Dysfunction and Impact of Eplerenone.
Mak, G.J., Ledwidge, M.T., Watson, C.J., Phelan, D.M., Dawkins, I.R., Murphy, N.F., Patle, A.K., Baugh, J.A., McDonald, K.M.
J Am Coll Cardiol. 2009
IL-13 expression by blood T cells and not eosinophils is increased in asthma compared to non-asthmatic eosinophilic bronchitis.
Siddiqui, S., Cruse, G., McKenna, S., Monteiro, W., Mistry, V., Wardlaw, A., Brightling, C.
BMC Pulmonary Medicine. 2009
Tumor necrosis factor-alpha regulates inflammatory and mesenchymal responses via mitogen-activated protein kinase kinase, p38, and nuclear factor kappaB in human endometriotic epithelial cells.
Grund, E.M., Kagan, D., Tran, C.A., Zeitvogel, A., Starzinski-Powitz, A., Nataraja, S., Palmer, S.S.
Mol Pharmacol. 2008
TLR7 Agonist 852A Inhibition of Tumor Cell Proliferation Is Dependent on Plasmacytoid Dendritic Cells and Type I IFN.
Inglefield, J.R., Dumitru, C.D., Alkan, S.S., Gibson, S.J., Lipson, K.E., Tomai, M.A., Larson, C.J., Vasilakos, J.P.
J Interferon Cytokine Res. 2008
Simultaneous Detection of Eight Analytes in Human Serum by Two Commercially Available Platforms for Multiplex Cytokine Analysis.
Toedter, G., Hayden, K., Wagner, C., Brodmerkel, C.
Clin Vaccine Immunol. 2008
Toll-like receptor (TLR) 2-9 agonists-induced Cytokines & Chemokines: I. Comparison with T cell receptor-induced responses.
Ghosh, T.K., Michelson, D.J., Fink, J., Solberg, J.C., Inglefield, J.R., Hook, D., Gupta, S.K., Gibson, S., Alkan, S.S.
Cell Immunol. 2006
Fetal-placental inflammation, but not adrenal activation, is associated with extreme preterm delivery.
Trivedi S, Joachim M, McElrath T, Kliman HJ, Allred EN, Fichorova RN, Onderdonk A, Heitor F, Chaychi L, Leviton A, Majzoub JA; ELGAN study investigators.
Am J Obstet Gynecol. 2011
Profiling of sputum inflammatory mediators in asthma and chronic obstructive pulmonary disease.
Bafadhel M, McCormick M, Saha S, McKenna S, Shelley M, Hargadon B, Mistry V, Reid C, Parker D, Dodson P, Jenkins M, Lloyd A, Rugman P, Newbold P, Brightling CE.
Respiration. 2012
CCL2 Is Associated with a Faster Rate of Cognitive Decline during Early Stages of Alzheimer's Disease.
Westin, K, Buchhave, P, Nielsen, H, Minthon, L, Janciauskiene, S, Hansson, O.
PLoS One. 2012
A profile of immune response to herpesvirus is associated with radiographic joint damage in rheumatoid arthritis.
Davis JM 3rd, Knutson KL, Skinner JA, Strausbauch MA, Crowson CS, Therneau TM, Wettstein PJ, Matteson EL, Gabriel SE.
Arthritis Res Ther. 2012
LPS challenge in healthy subjects: An investigation of neutrophil chemotaxis mechanisms involving CXCR1 and CXCR2.
Aul R, Patel S, Summerhill S, Kilty I, Plumb J, Singh D.
Int Immunopharmacol. 2012
Blood protein concentrations in the first two postnatal weeks that predict bronchopulmonary dysplasia among infants born before the 28th week of gestation.
Bose, C., Laughon, M., Allred, E.N., Van Marter, L.J., O'shea, T.M., Ehrenkranz, R.A., Fichorova, R., Leviton, A; for the ELGAN Study Investigators.
Pediatr Res. 2011
Posiphen as a candidate drug to lower CSF amyloid precursor protein, amyloid-β peptide and τ levels: target engagement, tolerability and pharmacokinetics in humans.
Maccecchini ML, Chang MY, Pan C, John V, Zetterberg H, Greig NH.
J Neurol Neurosurg Psychiatry. 2012
Changes in novel biomarkers of disease activity in juvenile and adult dermatomyositis are sensitive biomarkers of disease course.
Reed AM, Peterson E, Bilgic H, Ytterberg SR, Amin S, Hein MS, Crowson CS, Ernste F, Gillespie EB.
Arthritis Rheum. 2012
Phase 2 study of carlumab (CNTO 888), a human monoclonal antibody against CC-chemokine ligand 2 (CCL2), in metastatic castration-resistant prostate cancer.
Pienta KJ, Machiels JP, Schrijvers D, Alekseev B, Shkolnik M, Crabb SJ, Li S, Seetharam S, Puchalski TA, Takimoto C, Elsayed Y, Dawkins F, de Bono JS.
Invest New Drugs. 2012
Human parainfluenza virus serotypes differ in their kinetics of replication and cytokine secretion in human tracheobronchial airway epithelium.
Schaap-Nutt A, Liesman R, Bartlett EJ, Scull MA, Collins PL, Pickles RJ, Schmidt AC.
Virology. 2012
Systemic inflammation associated with severe intestinal injury in extremely low gestational age newborns.
Martin CR, Bellomy M, Allred EN, Fichorova RN, Leviton A.
Fetal Pediatr Pathol. 2012
Interferon inducible chemokines correlate with disease severity in systemic sclerosis.
Liu X, Mayes MD, Tan FK, Wu M, Reveille JD, Harper BE, Draeger HT, Gonzalez EB, Assassi S.
Arthritis Rheum. 2012
Systemic inflammation, intraventricular hemorrhage, and white matter injury.
Leviton A, Allred EN, Dammann O, Engelke S, Fichorova RN, Hirtz D, Kuban KC, Ment LR, O'shea TM, Paneth N, Shah B, Schreiber MD.
J Child Neurol. 2012
Barrier responses of human bronchial epithelial cells to grass pollen exposure.
Blume C, Swindle EJ, Dennison P, Jayasekera NP, Dudley S, Monk P, Behrendt H, Schmidt-Weber CB, Holgate ST, Howarth PH, Traidl-Hoffmann C, Davies DE.
Eur Respir J. 2012
Inhibition of cholesteryl ester transfer protein by anacetrapib does not impair the anti-inflammatory properties of high density lipoprotein.
Han S, Levoci L, Fischer P, Wang SP, Gagen K, Chen Y, Xie D, Fisher T, Ehrhardt AG, Peier AM, Johns DG.
Biochim Biophys Acta 2012
Critical role for apoptosis signal-regulating kinase 1 in the development of inflammatory K/BxN serum-induced arthritis.
Mnich, S.J., Blanner, P.M., Hu, G., Shaffer, A.F., Happa, F.A., O'Neil, S., Ukairo, O., Weiss, D., Welsh, E., Storer, C., Mbalaviele, G., Ichijo, H., Monahan, J.B., Hardy, M.M., Eda, H.
Int Immunopharmacol. 2010
Anti-inflammatory cytokines, pro-fibrogenic chemokines and persistence of acute HCV infection.
Osburn WO, Levine JS, Chattergoon MA, Thomas DL, Cox AL.
Journal of Viral Hepatitis 2013
Phase II study of a neutrophil elastase inhibitor (AZD9668) in patients with bronchiectasis.
Stockley R, De Soyza A, Gunawardena K, Perrett J, Forsman-Semb K, Entwistle N, Snell N.
Respir Med 2013
Idiopathic normal-pressure hydrocephalus: Pathophysiology and diagnosis by CSF biomarkers.
Jeppsson A, Zetterberg H, Blennow K, Wikkelso C.
Neurology 2013
The TARC/sICAM5 ratio in patient plasma is a candidate biomarker for drug resistant epilepsy
Pollard JR, Eidelman O, Mueller GP, Dalgard CL, Crino PB, Anderson CT, Brand EJ, Burakgazi E, Ivaturi SK, Pollard HB.
Front Neurol 2012



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