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Human Total PYY Kit
Peptide-YY (PYY) is a 36-amino acid peptide secreted from the intestinal L-cells of the gastrointestinal tract in proportion to the caloric content of a meal. Two endogenous forms, PYY(1-36) and PYY(3-36), are released into circulation; PYY(3-36) is the major form (60%) of PYY in gut mucosal endocrine cells and in the blood stream. This form results from the cleavage of PYY by the enzyme dipeptidyl peptidase-IV (DPP-IV). Some studies have reported that obese individuals have lower basal fasting levels of PYY(3-36) and have a smaller rise in postprandial levels suggesting PYY may be a potential therapeutic target in obesity. The Human Total PYY Kit provides a plate pre-coated with streptavidin (the user adds human PYY capture antibody conjugated to biotin) and the assay-specific components for the quantitative determination of endogenous PYY(1-36) and PYY(3-36) in human serum, plasma and cell supernatant.

Product Detail
Application Metabolic Markers
Analyte PYY
Species Human
Instrument SI2400, SI6000
Plate Type 96-well singleplex
 
Documents
Title Lot Number
doc Product insert
doc Data sheet
Product Options
Catalog No. Product Name Size
K151MPD-1 Human Total PYY Kit 1 plate
K151MPD-4 Human Total PYY Kit 25 plates
Additional Information
Related Publications Journal Year  
Consumption of buckwheat modulates the post-prandial response of selected gastrointestinal satiety hormones in individuals with type 2 diabetes mellitus.
Stringer DM, Taylor CG, Appah P, Blewett H, Zahradka P.
Metabolism 2013
Price and Availability
Price Please call for price
Size 5 plates
Catalog No. K151MPD-2
Availability Usually ships within 3 weeks

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