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Human IL-12p70 Base Kit
The Human IL-12p70 Base Kit provides basic components for the quantitative determination of both natural and recombinant human interleukin-12p70 (IL-12p70). Base kits generally include only MSD plates coated with the capture antibody, SULFO-TAG®-labeled antibody, and MSD proprietary read buffer. (See product insert for a list of kit components.) Base kits are most commonly used for high-throughput screening and assay development.

Product Detail
Application Cytokines & Chemokines
Analyte IL-12 p70
Species Human
Instrument SI2400, SI6000
Plate Type 96-well singleplex
 
Documents
Title Lot Number
doc Data sheet
doc Product insert
Product Options
Catalog No. Product Name Size
K151ARA-4 Human IL-12p70 Base Kit 25 plates
Additional Information
Related Publications Journal Year  
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Size 250 plates
Catalog No. K151ARA-5
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Related Publications Journal Year  
Short-term walnut consumption increases circulating total adiponectin and apolipoprotein A concentrations, but does not affect markers of inflammation or vascular injury in obese humans with the metabolic syndrome: data from a double-blinded, randomized, placebo-controlled study.
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Metabolism. 2011
Mycobacterium tuberculosis infection induces non-apoptotic cell death of human dendritic cells.
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BMC Microbiol. 2011
MTRX1011A, a humanized anti-CD4 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: A Phase I randomized, double-blind, placebo-controlled study incorporating pharmacodynamic biomarker assessments.
Scheerens, H., Su, Z., Irving, B., Townsend, M.J., Zheng, Y., Stefanich, E., Chindalore, V., Bingham, C.O. 3rd, Davis, J.C. Jr.
Arthritis Res Ther. 2011
Placental growth factor and soluble c-kit receptor dynamics characterize the cytokine signature of imatinib in prostate cancer and bone metastases.
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Neonatal Cytokine Profile in the Airway Mucosal Lining Fluid is skewed by Maternal Atopy.
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Maturation of human dendritic cells with Saccharomyces cerevisiae (yeast) reduces the number and function of regulatory T cells and enhances the ratio of antigen-specific effectors to regulatory T cells.
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AIDS 2011
Tobacco smoke exposure and altered nasal responses to live attenuated influenza virus.
Noah, T.L., Zhou, H., Monaco, J., Horvath, K., Herbst, M., Jaspers, I.
Environ Health Perspect. 2011
Microparticles (ectosomes) shed by stored human platelets downregulate macrophages and modify the development of dendritic cells.
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High-dose zidovudine plus valganciclovir for Kaposi sarcoma herpesvirus-associated multicentric Castleman disease: a pilot study of virus-activated cytotoxic therapy.
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Invest Ophthalmol Vis Sci. 2011
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Elevated levels of inflammatory cytokines predict survival in idiopathic and familial pulmonary arterial hypertension.
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Natural innate cytokine response to immunomodulators and adjuvants in human precision-cut lung slices.
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Toxicol Appl Pharmacol. 2010
Transforming growth factor beta is a major regulator of human neonatal immune responses following respiratory syncytial virus infection.
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J Virol. 2010
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Validation and comparison of two multiplex technologies, Luminex® and Mesoscale Discovery, for human cytokine profiling.
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Plasma cytokine profiles in systemic sclerosis: associations with autoantibody subsets and clinical manifestations.
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Arthritis Res Ther. 2009
Dexamethasone-pDMAEMA polymeric conjugates reduce inflammatory biomarkers in human intestinal epithelial monolayers.
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J Control Release. 2009
High sensitivity cytokine detection in acute coronary syndrome reveals up-regulation of Interferon Gamma and Interleukin-10 post Myocardial Infarction.
Patel, K.D., Duggan, S.P., Currid, C.A., Gallagher, W.M., McManus, R., Kelleher, D., Murphy, R.T., Ryan, A.W.
Clinical Immunology. 2009
Microbial translocation, the innate cytokine response, and HIV-1 disease progression in Africa.
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Proc Natl Acad Sci USA. 2009
Human dendritic cell maturation and activation by a heat-killed recombinant yeast (Saccharomyces cerevisiae) vector encoding carcinoembryonic antigen.
Remondo, C., Cereda, V., Mostbock, S., Sabzevari, H., Franzusoff, A., Schlom, J., Tsang, K.Y.
Vaccine. 2009
IL-13 expression by blood T cells and not eosinophils is increased in asthma compared to non-asthmatic eosinophilic bronchitis.
Siddiqui, S., Cruse, G., McKenna, S., Monteiro, W., Mistry, V., Wardlaw, A., Brightling, C.
BMC Pulmonary Medicine. 2009
IL-4 protein expression and basal activation of Erk in vivo in follicular lymphoma.
Calvo, K.R., Dabir, B., Kovach, A., Devor, C., Bandle, R., Bond, A., Shih, J.H., Jaffe, E.S.
Blood 2008
HIV infection-associated immune activation occurs by two distinct pathways that differentially affect CD4 and CD8 T cells.
Catalfamo, M., Di Mascio, M., Hu, Z., Srinivasula, S., Thaker, V., Adelsberger, J., Rupert, A., Baseler, M., Tagaya, Y., Roby, G., Rehm, C., Follmann, D., Lane, H.C.
PNAS. 2008
Lactoferrin acts as an alarmin to promote the recruitment and activation of APCs and antigen-specific immune responses.
de la Rosa, G., Yang, D., Tewary, P., Varadhachary, A., Oppenheim, J.J.
J Immunol Methods 2008
TLR7 Agonist 852A Inhibition of Tumor Cell Proliferation Is Dependent on Plasmacytoid Dendritic Cells and Type I IFN.
Inglefield, J.R., Dumitru, C.D., Alkan, S.S., Gibson, S.J., Lipson, K.E., Tomai, M.A., Larson, C.J., Vasilakos, J.P.
J Interferon Cytokine Res. 2008
Impaired dendritic cell maturation and cytokine production in patients with chronic mucocutanous candidiasis with or without APECED.
Ryan, K.R., Hong, M., Arkwright, P.D., Gennery, A.R., Costigan, C., Dominguez, M., Denning, D., McConnell, V., Cant, A.J., Abinun, M., Spickett, G.P., Lilic, D.
Clin Exp Immunol. 2008
TLR-TLR cross talk in human PBMC resulting in synergistic and antagonistic regulation of type-1 and 2 interferons, IL-12 and TNF-alpha.
Ghosh, T.K., Michelson, D.J., Solberg, J.C., Lipson, K.E., Inglefield, J.R., Alkan, S.S.
Int Immunopharmacol. 2007
Staphylococcus aureus enterotoxin B, protein A, and lipoteichoic acid stimulations in nasal polyps.
Patou, J., Gevaert, P., Van Zele, T., Holtappels, G., van Cauwenberge, P., Bachert, C.
J Allergy Clin Immunol. 2007
Selective leukemic-cell killing by a novel functional class of thalidomide analogs.
Ge, Y., Montano, I., Rustici, G., Freebern, W.J., Haggerty, C.M., Cui, W., Ponciano-Jackson, D., Chandramouli, G.V., Gardner, E.R., Figg, W.D., Abu-Asab, M., Tsokos, M., Jackson, S.H., Gardner. K.
Blood 2006
Toll-like receptor (TLR) 2-9 agonists-induced Cytokines & Chemokines: I. Comparison with T cell receptor-induced responses.
Ghosh, T.K., Michelson, D.J., Fink, J., Solberg, J.C., Inglefield, J.R., Hook, D., Gupta, S.K., Gibson, S., Alkan, S.S.
Cell Immunol. 2006
Pharmacologic profiling of transcriptional targets deciphers promoter logic.
Freebern, W.J., Haggerty, C.M., Montano, I., McNutt, M.C., Collins, I., Graham, A., Chandramouli, G.V.R., Stewart, D.H., Biebuyck, H.A., Taub, D.D., Gardner, K.
Pharmacogenomics J. 2005
Insulin resistance is associated with a metabolic profile of altered protein metabolism in Chinese and Asian-Indian men.
Tai, E.S., Tan, M.L., Stevens, R.D., Low, Y.L., Muehlbauer, M.J., Goh, D.L., Ilkayeva, O.R., Wenner, B.R., Bain, J.R., Lee, J.J., Lim, S.C., Khoo, C.M., Shah, S.H., Newgard, C.B.
Diabetologia 2010
Novel structurally related compounds reactivate latent HIV-1 in a bcl-2-transduced primary CD4+ T cell model without inducing global T cell activation.
Xing S, Bhat S, Shroff NS, Zhang H, Lopez JA, Margolick JB, Liu JO, Siliciano RF.
J Antimicrob Chemother. 2012
Qualitative Differences in T cell responses to Live, Attenuated and Inactivated Influenza Vaccines.
Eichelberger MC, Rivers KH, Ream R, Gao J, Hassantoufighi A, Straight TM.
J Clin Cell Immunol. 2011
Langerhans cells from human cutaneous squamous cell carcinoma induce strong type 1 immunity.
Fujita H, Suárez-Fariñas M, Mitsui H, Gonzalez J, Bluth MJ, Zhang S, Felsen D, Krueger JG, Carucci JA.
J Invest Dermatol. 2012
Natural-source d-α-tocopheryl acetate inhibits oxidant stress and modulates atopic asthma in humans in vivo.
Hoskins A, Roberts JL 2nd, Milne G, Choi L, Dworski R.
Allergy. 2012
Bananas as an Energy Source during Exercise: A Metabolomics Approach.
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PLoS One. 2012
Efficiency of log wood combustion affects the toxicological and chemical properties of emission particles.
Tapanainen M, Jalava PI, Mäki-Paakkanen J, Hakulinen P, Lamberg H, Ruusunen J, Tissari J, Jokiniemi J, Hirvonen MR.
Inhal Toxicol. 2012
Synthetic double-stranded RNA induces innate immune responses similar to a live viral vaccine in humans.
Caskey M, Lefebvre F, Filali-Mouhim A, Cameron MJ, Goulet JP, Haddad EK, Breton G, Trumpfheller C, Pollak S, Shimeliovich I, Duque-Alarcon A, Pan L, Nelkenbaum A, Salazar AM, Schlesinger SJ, Steinman RM, Sékaly RP.
J Exp Med. 2011
Phase II Study of Bevacizumab in Patients With HIV-Associated Kaposi's Sarcoma Receiving Antiretroviral Therapy.
Uldrick TS, Wyvill KM, Kumar P, O'Mahony D, Bernstein W, Aleman K, Polizzotto MN, Steinberg SM, Pittaluga S, Marshall V, Whitby D, Little RF, Yarchoan R.
J Clin Oncol. 2012
Sarcoidosis and Tuberculosis Cytokine Profiles: Indistinguishable in Bronchoalveolar Lavage but Different in Blood.
Thillai M, Eberhardt C, Lewin AM, Potiphar L, Hingley-Wilson S, Sridhar S, Macintyre J, Kon OM, Wickremasinghe M, Wells A, Weeks ME, Mitchell D, Lalvani A.
PLoS One 2012
Optimisation of grass pollen nasal allergen challenge for assessment of clinical and immunological outcomes.
Scadding GW, Calderon MA, Bellido V, Koed GK, Nielsen NC, Lund K, Togias A, Phippard D, Turka LA, Hansel TT, Durham SR, Wurtzen PA.
J Immunol Methods. 2012
Comparison of Multiplex Immunoassay Platforms.
Fu, Q., Zhu, J., Van Eyk, J.E.
Clinical Chemistry. 2010
A key role for the endothelium in NOD1 mediated vascular inflammation: comparison to TLR4 responses.
Gatheral T, Reed DM, Moreno L, Gough PJ, Votta BJ, Sehon CA, Rickard DJ, Bertin J, Lim E, Nicholson AG, Mitchell JA.
PLoS One. 2012
Chia seed supplementation and disease risk factors in overweight women: a metabolomics investigation.
Nieman DC, Gillitt N, Jin F, Henson DA, Kennerly K, Shanely RA, Ore B, Su M, Schwartz S.
J Altern Complement Med. 2012
Changes in serum and cerebrospinal fluid cytokines in response to non-neurological surgery: an observational study.
Bromander S, Anckarsäter R, Kristiansson M, Blennow K, Zetterberg H, Anckarsäter H, Wass CE.
J Neuroinflammation. 2012
Influence of red pepper spice and turmeric on inflammation and oxidative stress biomarkers in overweight females: A metabolomics approach.
Nieman DC, Cialdella-Kam L, Knab AM, Shanely RA.
Plant Foods Hum Nutr. 2012
Monocytes and γδ T cells control the acute phase response to intravenous zoledronate: Insights from a phase IV safety trial.
Welton JL, Morgan MP, Martí S, Stone MD, Moser B, Sewell AK, Turton J, Eberl M.
J Bone Miner Res. 2012
Experimental pain and opioid analgesia in volunteers at high risk for obstructive sleep apnea
Doufas AG, Tian L, Padrez KA, Suwanprathes P, Cardell JA, Maecker HT, Panousis P.
PLoS One 2013
Correlation between cytokine levels and changes in fatigue and quality of life in patients with acute myeloid leukemia.
Fung FY, Li M, Breunis H, Timilshina N, Minden MD, Alibhai SM.
Leuk Res. 2013
Glutathione S-transferase P1 Ile105Val polymorphism modulates allergen-induced airway inflammation in human atopic asthmatics in vivo
Hoskins A, Wu P, Reiss S, Dworski R.
Clinical & Experimental Allergy 2013
Association of IL-12p70 and IL-6:IL-10 ratio with autism-related behaviors in 22q11.2 deletion syndrome: A preliminary report.
Ross H, Guo Y, Coleman K, Ousley O, Miller A.
Brain Behav Immun 2013
TRIF-mediated TLR3 and TLR4 signaling is negatively regulated by ADAM15.
Ahmed S, Maratha A, Butt AQ, Shevlin E, Miggin SM.
J Immunol 2013
Helicobacter pylori-induced disruption of monolayer permeability and proinflammatory cytokine secretion in polarized human gastric epithelial cells.
Fiorentino M, Ding H, Blanchard TG, Czinn SJ, Sztein MB, Fasano A.
Infect Immun 2013
Anti-inflammatory cytokines, pro-fibrogenic chemokines and persistence of acute HCV infection.
Osburn WO, Levine JS, Chattergoon MA, Thomas DL, Cox AL.
Journal of Viral Hepatitis 2013
The TARC/sICAM5 ratio in patient plasma is a candidate biomarker for drug resistant epilepsy
Pollard JR, Eidelman O, Mueller GP, Dalgard CL, Crino PB, Anderson CT, Brand EJ, Burakgazi E, Ivaturi SK, Pollard HB.
Front Neurol 2012



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