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Human IL-6 Ultra-Sensitive Kit
This kit provides assay-specific components for the quantitative determination of both natural and recombinant human interleukin-6 (IL-6) in serum and plasma.

Product Detail
Application Cytokines & Chemokines
Analyte IL-6
Species Human
Instrument SI2400, SI6000
Plate Type 96-well singleplex
 
Documents
Title Lot Number
doc Data sheet
doc Product insert
Product Options
Catalog No. Product Name Size
K151AKC-4 Human IL-6 Ultra-Sensitive Kit 25 plates
K151AKC-2 Human IL-6 Ultra-Sensitive Kit 5 plates
Additional Information
Related Publications Journal Year  
Critical Appraisal of Four IL-6 Immunoassays.
Thompson, DK, Huffman, KM, Kraus, WE, Kraus, VB.
PLoS One. 2012
Short-term walnut consumption increases circulating total adiponectin and apolipoprotein A concentrations, but does not affect markers of inflammation or vascular injury in obese humans with the metabolic syndrome: data from a double-blinded, randomized, placebo-controlled study.
Aronis, K.N., Vamvini, M.T., Chamberland, J.P., Sweeney, L.L., Brennan, A.M., Magkos, F., Mantzoros, C.S.
Metabolism. 2011
Enhanced peripheral toll-like receptor responses in psychosis: further evidence of a pro-inflammatory phenotype.
McKernan, D.P., Dennison, U., Gaszner, G., Cryan, J.F., Dinan, T.G.
Translational Psychiatry 2011
Mycobacterium tuberculosis infection induces non-apoptotic cell death of human dendritic cells.
Ryan, R.C., O'Sullivan, M.P., Keane, J.
BMC Microbiol. 2011
MTRX1011A, a humanized anti-CD4 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: A Phase I randomized, double-blind, placebo-controlled study incorporating pharmacodynamic biomarker assessments.
Scheerens, H., Su, Z., Irving, B., Townsend, M.J., Zheng, Y., Stefanich, E., Chindalore, V., Bingham, C.O. 3rd, Davis, J.C. Jr.
Arthritis Res Ther. 2011

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Related Publications Journal Year  
Critical Appraisal of Four IL-6 Immunoassays.
Thompson, DK, Huffman, KM, Kraus, WE, Kraus, VB.
PLoS One. 2012
Short-term walnut consumption increases circulating total adiponectin and apolipoprotein A concentrations, but does not affect markers of inflammation or vascular injury in obese humans with the metabolic syndrome: data from a double-blinded, randomized, placebo-controlled study.
Aronis, K.N., Vamvini, M.T., Chamberland, J.P., Sweeney, L.L., Brennan, A.M., Magkos, F., Mantzoros, C.S.
Metabolism. 2011
Enhanced peripheral toll-like receptor responses in psychosis: further evidence of a pro-inflammatory phenotype.
McKernan, D.P., Dennison, U., Gaszner, G., Cryan, J.F., Dinan, T.G.
Translational Psychiatry 2011
Mycobacterium tuberculosis infection induces non-apoptotic cell death of human dendritic cells.
Ryan, R.C., O'Sullivan, M.P., Keane, J.
BMC Microbiol. 2011
MTRX1011A, a humanized anti-CD4 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: A Phase I randomized, double-blind, placebo-controlled study incorporating pharmacodynamic biomarker assessments.
Scheerens, H., Su, Z., Irving, B., Townsend, M.J., Zheng, Y., Stefanich, E., Chindalore, V., Bingham, C.O. 3rd, Davis, J.C. Jr.
Arthritis Res Ther. 2011
Placental growth factor and soluble c-kit receptor dynamics characterize the cytokine signature of imatinib in prostate cancer and bone metastases.
Mathew, P., Wen, S., Morita, S., Thall, P.F.
J Interferon Cytokine Res. 2011
High plasma interleukin-18 levels mark the acute phase of hepatitis C virus infection.
Chattergoon, M.A., Levine, J.S., Latanich, R., Osburn, W.O., Thomas, D.L., Cox, A.L.
J Infect Dis. 2011
Omega-3 supplementation lowers inflammation and anxiety in medical students: A randomized controlled trial.
Kiecolt-Glaser, J.K., Belury, M.A., Andridge, R., Malarkey, W.B., Glaser, R.
Brain Behav Immun. 2011
Inflammatory responses to trivalent influenza virus vaccine among pregnant women.
Christian, L.M., Iams, J.D., Porter, K., Glaser, R.
Vaccine. 2011
IL6-STAT3-HIF signaling and therapeutic response to the angiogenesis inhibitor sunitinib in ovarian clear cell cancer.
Anglesio, M.S., George, J., Kulbe, H., Friedlander, M., Rischin, D., Lemech, C., Power, J., Coward, J., Cowin, P.A., House, C.M., Chakravarty, P., Gorringe, K.L., Campbell, I.G.; Australian Ovarian Cancer Study Group, Okamoto, A., Birrer, M.J., Huntsman, D.G., de Fazio, A., Kalloger, S.E., Balkwill, F., Gilks, C.B., Bowtell, D.D.
Clin Cancer Res. 2011
Endothelial dysfunction and low-grade inflammation are associated with greater arterial stiffness over a 6-year period.
van Bussel, B.C., Schouten, F., Henry, R.M., Schalkwijk, C.G., de Boer, M.R., Ferreira, I., Smulders, Y.M., Twisk, J.W., Stehouwer, C.D.
Hypertension. 2011
Can emerging biomarkers of myocardial remodelling identify asymptomatic hypertensive patients at risk for diastolic dysfunction and diastolic heart failure?
Collier, P., Watson, C.J., Voon, V., Phelan, D., Jan, A., Mak, G., Martos, R., Baugh, J.A., Ledwidge, M.T., McDonald, K.M.
Eur J Heart Fail. 2011
Immediate and long-term effects of addition of exercise to a 16-week very low calorie diet on low-grade inflammation in obese, insulin-dependent type 2 diabetic patients.
Snel, M., Diepen, J.A., Stijnen, T., Pijl, H., Romijn, J.A., Edo Meinders, A., Voshol, P., Jazet, I.M.
Food Chem Toxicol. 2011
Cellular mechanism of insulin resistance in nonalcoholic fatty liver disease.
Kumashiro, N., Erion, D.M., Zhang, D., Kahn, M., Beddow, S.A., Chu, X., Still, C.D., Gerhard, G.S., Han, X., Dziura, J., Petersen, K.F., Samuel, V.T., Shulman, G.I.
Proc Natl Acad Sci U S A. 2011
Blood protein concentrations in the first two postnatal weeks associated with early postnatal blood gas derangements among infants born before the 28th week of gestation. The ELGAN Study.
Leviton, A., Allred, E.N., Kuban, K.C., Dammann, O., Fichorova, R.N., O'Shea, T.M., Paneth, N.; for the ELGAN Study Co-Investigators.
Cytokine. 2011
Persistence after birth of systemic inflammation associated with umbilical cord inflammation.
Leviton, A., Hecht, J.L., Allred, E.N., Yamamoto, H., Fichorova, R.N., Dammann, O.; for the ELGAN Study Investigators.
J Reprod Immunol. 2011
Cluster Analysis of Placental Inflammatory Proteins Can Distinguish Preeclampsia from Preterm Labor and Premature Membrane Rupture in Singleton Deliveries Less Than 28 Weeks of Gestation.
Faupel-Badger, J.M., Fichorova, R.N., Allred, E.N., Hecht, J.L., Dammann, O., Leviton, A., McElrath, T.F.
Am J Reprod Immunol. 2011
Cigarette smoke increases TLR4 and TLR9 expression and induces cytokine production from CD8+ T cells in chronic obstructive pulmonary disease.
Nadigel, J., Prefontaine, D., Baglole, C.J., Bourbeau, J., Maltais, F., Eidelman, D.H., Hamid, Q.
Respir Res. 2011
A Pilot Study of MUC-1/CEA/TRICOM Poxviral-Based Vaccine in Patients with Metastatic Breast and Ovarian Cancer.
Mohebtash, M., Tsang, K.Y., Madan, R.A., Huen, N.Y., Poole, D.J., Jochems, C., Jones, J., Ferrara, T., Heery, C.R., Arlen, P.M., Steinberg, S.M., Pazdur, M., Rauckhorst, M., Jones, E.C., Dahut, W.L., Schlom, J., Gulley, J.L.
Clin Cancer Res. 2011
Systemic responses of preterm newborns with presumed or documented bacteremia.
Leviton, A., O'Shea, M.T., Bednarek, F.J., Allred, E.N., Fichorova, R.N., Dammann, O.; for the ELGAN Study Investigators.
Acta Paediatr. 2011
Maintenance of a positive outlook during acute stress protects against pro-inflammatory reactivity and future depressive symptoms.
Aschbacher, K., Epel, E., Wolkowitz, O.M., Prather, A.A., Puterman, E., Dhabhar, F.S.
Brain, Behavior, and Immunity. 2011
Tumour tissue microenvironment can inhibit dendritic cell maturation in colorectal cancer.
Michielsen, A.J., Hogan, A.E., Marry, J., Tosetto, M., Cox, F., Hyland, J.M., Sheahan, K.D., O'Donoghue, D.P., Mulcahy, H.E., Ryan, E.J., O'Sullivan, J.N.
PLoS One. 2011
Mitochondrial mutagenesis correlates with the local inflammatory environment in arthritis.
Harty, L.C., Biniecka, M., O’Sullivan, J., Fox, E., Mulhall, K., Veale, D.J., Fearon, U.
Ann Rheum Dis. 2011
Tumor necrosis factor-alpha regulates inflammatory and mesenchymal responses via mitogen-activated protein kinase kinase, p38, and nuclear factor kappaB in human endometriotic epithelial cells.
Grund, E.M., Kagan, D., Tran, C.A., Zeitvogel, A., Starzinski-Powitz, A., Nataraja, S., Palmer, S.S.
Mol Pharmacol. 2008
Pharmacological properties of SD-282 - an alpha-isoform selective inhibitor for p38 MAP kinase.
Koppelman, B., Webb, H.K., Medicherla, S., Almirez, R., Feng, Y., Chavez, J.C., Mao, C.P., Nguyen, A., Liu, Y.W., Kapoun, A.M., Muiru, G., Huang, Y.A., Dugar, S., Mavunkel, B.J., Lim, D.W., Chakravarty, S., Luedtke, G., Protter, A.A., Higgins, L.S.
Pharmacology. 2008
The antileukemia activity of a human anti-CD40 antagonist antibody, HCD122, on human chronic lymphocytic leukemia cells.
Luqman, M., Klabunde, S., Lin, K., Georgakis, G.V., Cherukuri, A., Holash, J., Goldbeck, C., Xu, X., Kadel, E.E. 3rd, Lee, S.H., Aukerman, S.L., Jallal, B., Aziz, N., Weng, W.K., Wierda, W., O'Brien, S., Younes, A.
Blood 2008
Omega-3 fatty acids effect on wound healing.
McDaniel, J.C., Belury, M., Ahijevych, K., Blakely, W.
Wound Repair Regen. 2008
Agents associated with lung inflammation induce similar responses in NCI-H292 lung epithelial cells.
Newland, N., Richter, A.
Toxicol In Vitro. 2008
Impaired dendritic cell maturation and cytokine production in patients with chronic mucocutanous candidiasis with or without APECED.
Ryan, K.R., Hong, M., Arkwright, P.D., Gennery, A.R., Costigan, C., Dominguez, M., Denning, D., McConnell, V., Cant, A.J., Abinun, M., Spickett, G.P., Lilic, D.
Clin Exp Immunol. 2008
Simultaneous Detection of Eight Analytes in Human Serum by Two Commercially Available Platforms for Multiplex Cytokine Analysis.
Toedter, G., Hayden, K., Wagner, C., Brodmerkel, C.
Clin Vaccine Immunol. 2008
Investigating Toll-like receptor agonists for potential to treat hepatitis C virus infection.
Thomas, A., Laxton, C., Rodman, J., Myangar, N., Horscroft, N., Parkinson, T.
Antimicrob Agents Chemother. 2007
Trichomonas vaginalis Lipophosphoglycan Triggers a Selective Upregulation of Cytokines by Human Female Reproductive Tract Epithelial Cells.
Fichorova, R.N., Trifonova, R.T., Gilbert, R.O., Costello, C.E., Hayes, G.R., Lucas, J.J., Singh, B.N.
Infection and Immunity. 2006
Selective leukemic-cell killing by a novel functional class of thalidomide analogs.
Ge, Y., Montano, I., Rustici, G., Freebern, W.J., Haggerty, C.M., Cui, W., Ponciano-Jackson, D., Chandramouli, G.V., Gardner, E.R., Figg, W.D., Abu-Asab, M., Tsokos, M., Jackson, S.H., Gardner. K.
Blood 2006
Predictors of elevated nuclear factor-kappaB-dependent genes in obstructive sleep apnea syndrome.
Ryan, S., Taylor, C.T., McNicholas, W.T.
Am J Res and Crit Care Med. 2006
Biocompatibility of solid-dosage forms of anti-human immunodeficiency virus type 1 microbicides with the human cervicovaginal mucosa modeled ex vivo.
Trifonova, R.T., Pasicznyk, J.M., Fichorova, R.N.
Antimicrobial Agents and Chemotherapy. 2006
Pharmacologic profiling of transcriptional targets deciphers promoter logic.
Freebern, W.J., Haggerty, C.M., Montano, I., McNutt, M.C., Collins, I., Graham, A., Chandramouli, G.V.R., Stewart, D.H., Biebuyck, H.A., Taub, D.D., Gardner, K.
Pharmacogenomics J. 2005
A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease.
Björkqvist, M., Wild, E.J., Thiele, J., Silvestroni, A., Andre, R., Lahiri, N., Raibon, E., Lee, R.V., Benn, C.L., Soulet, D., Magnusson, A., Woodman, B., Landles, C., Pouladi, M.A., Hayden, M.R., Khalili-Shirazi, A., Lowdell, M.W., Brundin, P., Bates, G.P., Leavitt, B.R., Möller, T., Tabrizi, S.J.
J Exp Med. 2008
Novel insights into the cellular mechanisms of the anti-inflammatory effects of NF-kB essential modulator (NEMO) binding domain peptides.
Baima, E.T., Guzova, J.A., Mathialagan, S., Nagiec, E.E., Hardy, M.M., Song, L.R., Bonar, S.L., Weinberg, R.A., Selness, S.R., Woodard, S.S., Chrencik, J., Hood, W.F., Schindler, J.F., Kishore, N., Mbalaviele, G.
J Biol Chem. 2010
Surface molecules on stimulated plasmacytoid dendritic cells are sufficient to cross-activate resting myeloid dendritic cells.
Cantisani, R., Sammicheli, C., Tavarini, S., D'Oro, U., Wack, A., Piccioli, D.
Hum Immunol. 2011
Multiplex measurement of proinflammatory cytokines in human serum: Comparison of the Meso Scale Discovery electrochemiluminescence assay and the Cytometric Bead Array.
Dabitao, D., Margolick, J.B., Lopez, J., Bream, J.H.
J Immunol Methods 2011
Proinflammatory cytokines, sickness behavior, and Alzheimer disease.
Holmes, C., Cunningham, C., Zotova, E., Culliford, D., Perry, V.H.
Neurology. 2011
Safety, Efficacy, and Biomarker Exploration in a Phase II Study of Bevacizumab, Oxaliplatin, and Gemcitabine in Recurrent Müllerian Carcinoma.
Horowitz, N.S., Penson, R.T., Duda, D.G., di Tomaso, E., Boucher, Y., Ancukiewicz, M., Cohen, K.S., Berlin, S., Krasner, C.N., Moses, M.A., Jain, R.K.
Clin Ovarian Cancer Other Gynecol Malig. 2011
A Small Molecule That Mimics the BB-loop in the Toll Interleukin-1 (IL-1) Receptor Domain of MyD88 Attenuates Staphylococcal Enterotoxin B-induced Pro-inflammatory Cytokine Production and Toxicity in Mice.
Kissner, T.L., Moisan, L., Mann, E., Alam, S., Ruthel, G., Ulrich, R.G., Rebek, M., Rebek, J. Jr, Saikh, K.U.
J Biol Chem. 2011
Assessing immune function by profiling cytokine release from stimulated blood leukocytes and the risk of infection in rheumatoid arthritis.
Krause, M.L., Davis, J.M. 3rd, Knutson, K.L., Strausbach, M.A., Crowson, C.S., Therneau, T.M., Wettstein, P.J., Matteson, E.L., Gabriel, S.E.
Clin Immunol. 2011
Variance in the Acute Inflammatory Response to Prolonged Cycling Is Linked to Exercise Intensity.
Nieman, D.C., Konrad, M., Henson, D.A., Kennerly, K., Shanely, R.A., Wallner-Liebmann, S.J.
J Interferon Cytokine Res. 2011
Tenascin-C induces inflammatory mediators and matrix degradation in osteoarthritic cartilage.
Patel, L., Sun, W., Glasson, S.S., Morris, E.A., Flannery, C.R., Chockalingam, P.S.
BMC Musculoskelet Disord. 2011
Increased levels of circulating interleukin 6, interleukin 8, C-reactive protein, and risk of lung cancer.
Pine, S.R., Mechanic, L.E., Enewold, L., Chaturvedi, A.K., Katki, H.A., Zheng, Y.L., Bowman, E.D., Engels, E.A., Caporaso, N.E., Harris, C.C.
J Natl Cancer Inst. 2011
High-Throughput Simultaneous Analysis of RNA, Protein, and Lipid Biomarkers in Heterogeneous Tissue Samples.
Reiser, V., Smith, R.C., Xue, J., Kurtz, M.M., Liu, R., Legrand, C., He, X., Yu, X., Wong, P., Hinchcliffe, J.S., Tanen, M.R., Lazar, G., Zieba, R., Ichetovkin, M., Chen, Z., O'Neill, E.A., Tanaka, W.K., Marton, M.J., Liao, J., Morris, M., Hailman, E., Tokiwa, G.Y., Plump, A.S.
Clin Chem. 2011
Acute Exacerbations of COPD: Identification of Biological Clusters and Their Biomarkers.
Bafadhel, M., McKenna, S., Terry, S., Mistry, V., Reid, C., Haldar, P., McCormick, M., Haldar, K., Kebadze, T., Duvoix, A., Lindblad, K., Patel, H., Rugman, P., Dodson, P., Jenkins, M., Saunders, M., Newbold, P., Green, R.H., Venge, P., Lomas, D.A., Barer, M.R., Johnston, S.L., Pavord, I.D., Brightling, C.E.
Am J Respir Crit Care Med. 2011
Higher Levels of CRP, D-dimer, IL-6, and Hyaluronic Acid Before Initiation of Antiretroviral Therapy (ART) Are Associated With Increased Risk of AIDS or Death.
Boulware, D.R., Hullsiek, K.H., Puronen, C.E., Rupert, A., Baker, J.V., French, M.A., Bohjanen, P.R., Novak, R.M., Neaton, J.D., Sereti, I; for the INSIGHT Study Group.
J Infect Dis. 2011
Maturation of human dendritic cells with Saccharomyces cerevisiae (yeast) reduces the number and function of regulatory T cells and enhances the ratio of antigen-specific effectors to regulatory T cells.
Cereda, V., Vergati, M., Huen, N.Y., di Bari, M.G., Jochems, C., Intrivici, C., Gulley, J.L., Apelian, D., Schlom, J., Tsang, K.Y.
Vaccine. 2011
Presurgical stress management improves postoperative immune function in men with prostate cancer undergoing radical prostatectomy.
Cohen, L., Parker, P.A., Vence, L., Savary, C., Kentor, D., Pettaway, C., Babaian, R., Pisters, L., Miles, B., Wei, Q., Wiltz, L., Patel, T., Radvanyi, L.
Psychosom Med. 2011
A signature of aberrant immune responsiveness identifies myocardial dysfunction in rheumatoid arthritis.
Davis, J.M. 3rd, Knutson, K.L., Strausbauch, M.A., Crowson, C.S., Therneau, T.M., Wettstein, P.J., Roger, V.L., Matteson, E.L., Gabriel, S.E.
Arthritis Rheum. 2011
Interleukin-1ß-induced interleukin-6 production in A549 cells is mediated by both phosphatidylinositol 3-kinase and interleukin-1 receptor-associated kinase-4.
Eda, H., Burnette, B.L., Shimada, H., Hope, H.R., Monahan, J.B.
Cell Biol Int. 2011
The Innate Immune Response, Clinical Outcomes, and Ex Vivo HCV Antiviral Efficacy of a TLR7 Agonist (PF-4878691).
Fidock, M.D., Souberbielle, B.E., Laxton, C., Rawal, J., Delpuech-Adams, O., Corey, T.P., Colman, P., Kumar, V., Cheng, J.B., Wright, K., Srinivasan, S., Rana, K., Craig, C., Horscroft, N., Perros, M., Westby, M., Webster, R., van der Ryst, E.
Clin Pharmacol Ther. 2011
Relationship Between Neonatal Blood Protein Concentrations and Placenta Histologic Characteristics in Extremely Low GA Newborns.
Hecht, J.L., Fichorova, R.N., Tang, V.F., Allred, E.N., McElrath, T.F., Leviton, A; Elgan Study Investigators.
Pediatr Res. 2011
The Antagonists But Not Partial Agonists of Glucocorticoid Receptor Ligands Show Substantial Side Effect Dissociation.
Hu, X., Du, S., Tunca, C., Braden, T., Long, K.R., Lee, J., Webb, E.G., Dietz, J.D., Hummert, S., Rouw, S., Hegde, S.G., Webber, R.K., Obukowicz, M.G.
Endocrinology 2011
A role for reactive oxygen species in endotoxin-induced elevation of MOR expression in the nervous and immune systems.
Langsdorf, E.F., Mao, X., Chang, S.L.
J Neuroimmunol. 2011
IL-6-independent association of elevated serum neopterin levels with prevalent frailty in community-dwelling older adult.
Leng, S.X., Tian, X., Matteini, A., Li, H., Hughes, J., Jain, A., Walston, J.D., Fedarko, N.S.
Age Ageing. 2011
Early postnatal blood concentrations of inflammation-related proteins and microcephaly two years later in infants born before the 28th post-menstrual week.
Leviton, A., Kuban, K.C., Allred, E.N., Fichorova, R.N., O'Shea, T.M., Paneth, N.; for the ELGAN Study Investigators.
Early Hum Dev. 2011
The Relationship between Early Concentrations of 25 Blood Proteins and Cerebral White Matter Injury in Preterm Newborns: The ELGAN Study.
Leviton, A., Kuban, K., O'Shea, T.M., Paneth, N., Fichorova, R., Allred, E.N., Dammann, O.
J Pediatr. 2011
Exchanging Saturated Fatty Acids for (n-6) Polyunsaturated Fatty Acids in a Mixed Meal May Decrease Postprandial Lipemia and Markers of Inflammation and Endothelial Activity in Overweight Men.
Masson, C.J., Mensink, R.P.
J Nutr. 2011
Placental Growth Factor and Soluble c-Kit Receptor Dynamics Characterize the Cytokine Signature of Imatinib in Prostate Cancer and Bone Metastases.
Mathew, P., Wen, S., Morita, S., Thall, P.F.
J Interferon Cytokine Res. 2011
Blood protein profiles of infants born before 28th week differ by pregnancy complication.
McElrath, T.F., Fichorova, R.N., Allred, E.N., Hecht, J.L., Ismail, M.A., Yuan, H., Leviton, A; ELGAN Study Investigators.
Am J Obstet Gynecol. 2011
Markers of endothelial dysfunction, coagulation and tissue fibrosis independently predict venous thromboembolism in HIV.
Musselwhite, L.W., Sheikh, V., Norton, T.D., Rupert, A., Porter, B.O., Penzak, S.R., Skinner, J., Mican, J.M., Hadigan, C., Sereti, I.
AIDS 2011
Blockade of Toll-like receptor 2 prevents spontaneous cytokine release from rheumatoid arthritis ex vivo synovial explant cultures.
Nic An Ultaigh, S., Saber, T.P., McCormick, J., Connolly, M., Dellacasagrande, J., Keogh, B., McCormack, W., Reilly, M., O'Neill, L.A., McGuirk, P., Fearon, U., Veale, D.J.
Arthritis Res Ther. 2011
Microparticles (ectosomes) shed by stored human platelets downregulate macrophages and modify the development of dendritic cells.
Sadallah, S., Eken, C., Martin, P.J., Schifferli, J.A.
J Immunol Methods 2011
Differential effects of HIV viral load and CD4 counts on proliferation of naive and memory CD4 and CD8 T lymphocytes.
Srinivasula, S., Lempicki, R.A., Adelsberger, J.W., Huang, C.Y., Roark, J., Lee, P.I., Rupert, A., Stevens, R., Sereti, I., Lane, H.C., Di Mascio, M., Kovacs, J.A.
Blood 2011
High-dose zidovudine plus valganciclovir for Kaposi sarcoma herpesvirus-associated multicentric Castleman disease: a pilot study of virus-activated cytotoxic therapy.
Uldrick, T.S., Polizzotto, M.N., Aleman, K., O'Mahony, D., Wyvill, K.M., Wang, V., Marshall, V., Pittaluga, S., Steinberg, S.M., Tosato, G., Whitby, D., Little, R.F., Yarchoan, R.
Blood 2011
Pentoxifylline for the treatment of non-alcoholic steatohepatitis: a randomized controlled trial.
Van Wagner, L.B., Koppe, S.W., Brunt, E.M., Gottstein, J., Gardikiotes, K., Green, R.M., Rinella, M.E.
Ann Hepatol 2011
Proteomic analysis of coronary sinus serum reveals leucine-rich a2-glycoprotein as a novel biomarker of ventricular dysfunction and heart failure
Watson, C.J., Ledwidge, M.T., Phelan, D., Collier, P., Byrne, J.C., Dunn, M.J., McDonald, K.M., Baugh, J.A.
Circ Heart Fail. 2011
Lipopolysaccharide Regulation of Toll-Like Receptor-4 and Matrix Metalloprotease-9 in Human Primary Corneal Fibroblast Cells.
Wong, Y., Sethu, C., Louafi, F., Hossain, P.
Invest Ophthalmol Vis Sci. 2011
The biochemical response to biomechanical tissue loading on the low back during physical work exposure.
Yang, G., Marras, W.S., Best, T.M.
Clin Biomech (Bristol, Avon). 2011
Exploratory analysis of early toxicity of sunitinib in advanced hepatocellular carcinoma patients: kinetics and potential biomarker value.
Zhu, A.X., Duda, D.G., Ancukiewicz, M., di Tomaso, E., Clark, J.W., Miksad, R., Fuchs, C.S., Ryan, D.P., Jain, R.K.
Clin Cancer Res. 2011
A Long-Acting Tumor Necrosis Factor a-Binding Protein Demonstrates Activity in Both In Vitro and In Vivo Models of Endometriosis.
Altan, Z.M., Denis, D., Kagan, D., Grund, E.M., Palmer, S.S., Nataraja, S.G.
J Pharmacol. 2010
Phase II study of cediranib, an oral pan-vascular endothelial growth factor receptor tyrosine kinase inhibitor, in patients with recurrent glioblastoma.
Batchelor, T.T., Duda, D.G., di Tomaso, E., Ancukiewicz, M., Plotkin, S.R., Gerstner, E., Eichler, A.F., Drappatz, J., Hochberg, F.H., Benner, T., Louis, D.N., Cohen, K.S., Chea, H., Exarhopoulos, A., Loeffler, J.S., Moses, M.A., Ivy, P., Sorensen, A.G., Wen, P.Y., Jain, R.K.
J Clin Oncol. 2010
Maternal Microbe-Specific Modulation of Inflammatory Response in Extremely Low-Gestational-Age Newborns
Fichorova, R.N., Onderdonk, A.B., Yamamoto, H., Delaney, M.L., DuBois, A.M., Allred, E., Levition, A; for the ELGAN Study Investigators.
mBio 2011
Raised interleukin-17 is immunolocalised to neutrophils in cystic fibrosis lung disease.
Brodlie, M., McKean, M.C., Johnson, G.E., Anderson, A.E., Hilkens, C.M., Fisher, A.J., Corris, P.A., Lordan, J.L., Ward, C.
Eur Respir J. 2011
Microbial translocation, the innate cytokine response, and HIV-1 disease progression in Africa.
Redd, A.D., Dabitao, D., Bream, J.H., Charvat, B., Laeyendecker, O., Kiwanuka, N., Lutalo, T., Kigozi, G., Tobian, A.A., Gamiel, J., Neal, J.D., Oliver, A.E., Margolick, J.B., Sewankambo, N., Reynolds, S.J., Wawer, M.J., Serwadda, D., Gray, R.H., Quinn, T.C.
Proc Natl Acad Sci USA. 2009
Generation of an epigenetic signature by chronic hypoxia in prostate cells.
Watson, J.A., Watson, C.J., McCrohan, A.M., Woodfine, K., Tosetto, M., McDaid, J., Gallagher, E., Betts, D., Baugh, J., O'Sullivan, J., Murrell, A., Watson, R.W., McCann, A.
Human Molecular Genetics. 2009
Efficacy, Safety, and Biomarkers of Neoadjuvant Bevacizumab, Radiation Therapy, and Fluorouracil in Rectal Cancer: A Multidisciplinary Phase II Study.
Willett, C.G., Duda, D.G., di Tomaso, E., Boucher, Y., Ancukiewicz, M., Sahani, D.V., Lahdenranta, J., Chung, D.C., Fischman, A.J., Lauwers, G.Y., Shellito, P., Czito, B.G., Wong, T.Z., Paulson, E., Poleski, M., Vujaskovic, Z., Bentley, R., Chen, H.X., Clark, J.W., Jain, R.K.
Journal of Clinical Oncology. 2009
Efficacy, Safety, and Potential Biomarkers of Sunitinib Monotherapy in Advanced Hepatocellular Carcinoma: A Phase II Study.
Zhu, A.X., Sahani, D.V., Duda, D.G., di Tomaso, E., Ancukiewicz, M., Catalano, O.A., Sindhwani, V., Blaszkowsky, L.S. Yoon, S.S., Lahdenranta, J., Bhargava, P., Meyerhardt, J. Clark, J.W., Kwak, E.L., Hezel, A.F., Miksad, R., Abrams, T.A., Enzinger, P.C., Fuchs, C.S., Ryan, D.P., Jain, R.K.
Journal of Clinical Oncology. 2009
Structural and functional characterization of disulfide isoforms of the human IGG2 subclass.
Dillon, T.M., Ricci, M.S., Vezina, C., Flynn, G.C. Liu, Y. D., Rehder, D.S., Plant, M., Henkle, B., Li, Y., Deechongkit, S., Varnum, B., Wypych, J., Balland, A., Bondarenko P. V.
J Biol Chem. 2008
Marital behavior, oxytocin, vasopressin, and wound healing.
Gouin, J.P., Carter, C.S., Pournajafi-Nazarloo, H., Glaser, R., Malarkey, W.B., Loving, T.J., Stowell, J., Kiecolt-Glaser, J.K.
Psychoneuroendocrinology. 2010
Assessing agonistic potential of a candidate therapeutic anti-IL21R antibody.
Guo, Y., Hill, A.A., Ramsey, R.C., Immermann, F.W., Corcoran, C., Young, D., Lavallie, E.R., Ryan, M., Bouchard, T., Pfeifer, R., Warner, G., Bologna, M., Bloom, L., O'Toole, M.
J Transl Med. 2010
Exercise-induced release of cytokines in patients with major depressive disorder.
Hallberg, L., Janelidze, S., Engstrom, G., Wisen, A.G., Westrin, A., Brundin, L.
J Affect Disord. 2010
The relationship between neonatal blood protein profiles and placenta histologic characteristics in extremely low gestation age newborns.
Hecht, J.L., Fichorova, R.N., Tang, V.F., Allred, E.N., McElrath, T.F., Leviton, A; for the ELGAN study investigators.
Pediatr Res. 2010
Cytokine levels in the blood may distinguish suicide attempters from depressed patients.
Janelidze, S., Mattei, D., Westrin, S., Träskman-Bendz, L., Brundin, L.
Brain Behavior and Immunity 2010
Inflammation-related proteins in the blood of extremely low gestational age newborns. The contribution of inflammation to the appearance of developmental regulation.
Leviton, A., Fichorova, R., Yamamoto, Y., Allred, E.N., Dammann, O., Hecht, J., Kuban, K., McElrath, T., O'Shea, T.M., Paneth, N.
Cytokine 2010
Substitution of the Bordetella pertussis lipid A phosphate groups with glucosamine is required for robust NF-kappaB activation and release of proinflammatory cytokines in cells expressing human but not murine Toll-like receptor 4-MD-2-CD14.
Marr, N., Hajjar, A.M., Shah, N.R., Novikov, A., Yam, C.S., Caroff, M., Fernandez, R.C.
Infect Immun. 2010
Transcriptional responses in the adaptation to ischaemia-reperfusion injury: a study of the effect of ischaemic preconditioning in total knee arthroplasty patients.
Murphy, T., Walsh, P.M., Doran, P.P., Mulhall, K.J.
J Transl Med. 2010
Effects of exercise combined with caloric restriction on inflammatory cytokines.
Reed, J.L., De Souza, M.J., Williams, N.I.
Appl Physiol Nutr Metab. 2010
Differential IL-17 production and mannan recognition contribute to fungal pathogenicity and commensalism.
Rizzetto, L., Kuka, M., De Filippo, C., Cambi, A., Netea, M.G., Beltrame, L., Napolitani, G., Torcia, M.G., D'Oro, U., Cavalieri, D.
J Immunol Methods 2010
Short-term IL-1beta blockade reduces monocyte CD11b integrin expression in an IL-8 dependent fashion in patients with type 1 diabetes.
Sanda, S., Bollyky, J., Standifer, N., Nepom, G., Hamerman, J.A., Greenbaum, C.
Clin Immunol. 2010
Elevated levels of inflammatory cytokines predict survival in idiopathic and familial pulmonary arterial hypertension.
Soon, E., Holmes, A.M., Treacy, C.M., Doughty, N.J., Southgate, L., Machado, R.D., Trembath, R.C., Jennings, S., Barker, L., Nicklin, P., Walker, C., Budd, D.C., Pepke-Zaba, J., Morrell, N.W.
Circulation. 2010
Transforming growth factor beta is a major regulator of human neonatal immune responses following respiratory syncytial virus infection.
Thornburg, N.J., Shepherd, B., Crowe, J.E. Jr.
J Virol. 2010
Omega-3 fatty acid supplements in women at high risk of breast cancer have dose-dependent effects on breast adipose tissue fatty acid composition.
Yee, L.D., Lester, J.L., Cole, R.M., Richardson, J.R., Hsu, J.C., Li, Y., Lehman, A., Belury, M.A., Clinton, S.K.
Am J Clin Nutr. 2010
Lymphotoxin-aß heterotrimers are cleaved by metalloproteinases and contribute to synovitis in rheumatoid arthritis.
Young, J., Yu, X., Wolslegel, K., Nguyen, A., Kung, C., Chiang, E., Kolumam, G., Wei, N., Wong, W.L., DeForge, L., Townsend, M.J., Grogan, J.L.
Cytokine 2010
A phase I pharmacokinetic and biological correlative study of IMP321, a novel MHC class II agonist, in patients with advanced renal cell carcinoma.
Brignone, C., Escudier, B., Grygar, C., Marcu, M., Triebel, F.
Clin Cancer Res. 2009
Amphipathic DNA polymers exhibit antiviral activity against systemic murine Cytomegalovirus infection.
Cardin, R.D., Bravo, F.J., Sewell, A.P., Cummins, J., Flamand, L., Juteau, J.M., Bernstein, D.I., Vaillant, A.
Virol J. 2009
Longitudinal cytokine expression during IMRT for prostate cancer and acute treatment toxicity.
Christensen, E., Pintilie, M., Evans, K.R., Lenarduzzi, M., Menard, C., Catton, C.N., Diamandis, E.P., Bristow, R.G.
Clin Cancer Res. 2009
Depressive symptoms are associated with elevated serum proinflammatory cytokines among pregnant women.
Christian, L.M., Franco, A., Glaser, R. Iams, J.D.
Brain, Behavior, and Immunity. 2009
An in vitro perfusion system to examine the responses of endothelial cells to simulated flow and inflammatory stimulation.
Cockcroft, N.Y., Oke, O., Cunningham, F., Bishop, E., Fearon, I.M., Zantl, R., Gaca, M.D.
Altern Lab Anim. 2009
Serum concentrations of cytokines and lung cancer survival in African Americans and Caucasians.
Enewold, L., Mechanic, L.E., Bowman, E.D., Zheng, Y.L., Yu, Z., Trivers, G., Alberg, A.J., Harris, C.C.
Cancer Epidemiol Biomarkers Prev. 2009
Plasma cytokine profiles in systemic sclerosis: associations with autoantibody subsets and clinical manifestations.
Gourh, P., Arnett, F.C., Assassi, S., Tan, F.K., Huang, M., Diekman, L., Mayes, M.D., Reveille, J.D., Agarwal, S.K.
Arthritis Res Ther. 2009
Serum molecular signatures of weight change during early breast cancer chemotherapy.
Keun, H.C., Sidhu, J., Pchejetski, D., Lewis, J.S., Marconell, H., Patterson, M., Bloom, S.R., Amber, V., Coombes, R.C., Stebbing, J.
Clin Cancer Res. 2009
Interleukin-6 Is Elevated in the Cerebrospinal Fluid of Suicide Attempters and Related to Symptom Severity.
Lindqvist, D., Janelidze, S., Hagell, P., Erhardt, S., Samuelsson, M., Minthon, L., Hansson, O., Björkqvist, M., Träskman-Bendz, L., Brundin, L.
Biol Psychiatry. 2009
Natural History of Markers of Collagen Turnover in Patients With Early Diastolic Dysfunction and Impact of Eplerenone.
Mak, G.J., Ledwidge, M.T., Watson, C.J., Phelan, D.M., Dawkins, I.R., Murphy, N.F., Patle, A.K., Baugh, J.A., McDonald, K.M.
J Am Coll Cardiol. 2009
Physical training after percutaneous coronary intervention in patients with stable angina: effects on working capacity, metabolism, and markers of inflammation.
Astengo, M., Dahl, A., Karlsson, T., Mattsson-Hultén, L., Wiklund, O., Wennerblom, B.
European Journal of Cardiovascular Prevention & Rehabilitation. 2009
A combination of ultrahigh throughput PathHunter and cytokine secretion assays to identify glucocorticoid receptor agonists.
Patel, A., Murray, J., McElwee-Whitmer, S., Bai, C., Kunapuli, P., Johnson, E.N.
Anal Biochem. 2009
High sensitivity cytokine detection in acute coronary syndrome reveals up-regulation of Interferon Gamma and Interleukin-10 post Myocardial Infarction.
Patel, K.D., Duggan, S.P., Currid, C.A., Gallagher, W.M., McManus, R., Kelleher, D., Murphy, R.T., Ryan, A.W.
Clinical Immunology. 2009
Cellular senescence induced by aberrant MAD2 levels impacts on paclitaxel responsiveness in vitro.
Prencipe, M., Fitzpatrick, P., Gorman, S., Tosetto, M., Klinger, R., Furlong, F., Harrison, M., O'Connor, D., Roninson, I.B., O'Sullivan, J., McCann, A.
Br J Cancer. 2009
Omega-3 fatty acid supplementation improves vascular function and reduces inflammation in obese adolescents.
Dangardt, F., Osika, W., Chen, Y., Nilsson, U., Gan, L.M., Gronowitz, E., Strandvik, B., Friberg, P.
Atherosclerosis. 2010
Analysis of complex biomarkers for human immune-mediated disorders based on cytokine responsiveness of peripheral blood cells.
Davis, J.M. 3rd, Knutson, K.L., Strausbauch, M.A., Crowson, C.S., Therneau, T.M., Wettstein, P.J., Matteson, E.L., Gabriel, S.E.
J Immunol Methods 2010
Down-regulation of p38 mitogen-activated protein kinase activation and proinflammatory cytokine production by mitogen-activated protein kinase inhibitors in inflammatory bowel disease.
Docena, G., Rovedatti, L., Kruidenier, L., Fanning, A., Leakey, N.A., Knowles, C.H., Lee, K., Shanahan, F., Nally, K., McLean, P.G., Di Sabatino, A., MacDonald, T.T.
Clin Exp Immunol. 2010
Macrophage-colony stimulating factor and interleukin-34 induce chemokines in human whole blood.
Eda, H., Zhang, J., Keith, R.H., Michener, M., Beidler, D.R., Monahan, J.B.
Cytokine 2010
Traditional risk factors and D-dimer predict incident cardiovascular disease events in chronic HIV infection.
Ford, E.S., Greenwald, J.H., Richterman, A.G., Rupert, A., Dutcher, L., Badralmaa, Y., Natarajan, V., Rehm, C., Hadigan, C., Sereti, I.
AIDS 2010
Insulin resistance is associated with a metabolic profile of altered protein metabolism in Chinese and Asian-Indian men.
Tai, E.S., Tan, M.L., Stevens, R.D., Low, Y.L., Muehlbauer, M.J., Goh, D.L., Ilkayeva, O.R., Wenner, B.R., Bain, J.R., Lee, J.J., Lim, S.C., Khoo, C.M., Shah, S.H., Newgard, C.B.
Diabetologia 2010
Phase II Study of Neoadjuvant Bevacizumab and Radiotherapy for Resectable Soft Tissue Sarcomas.
Yoon, S.S., Duda, D.G., Karl, D.L., Kim, T.M., Kambadakone, A.R., Chen, Y.L., Rothrock, C., Rosenberg, A.E., Nielsen, G.P., Kirsch, D.G., Choy, E., Harmon, D.C., Hornicek, F.J., Dreyfuss, J., Ancukiewicz, M., Sahani, D.V., Park, P.J., Jain, R.K., Delaney, T.F.
Int J Radiat Oncol Biol Phys. 2010
Biological and technical variables affecting immunoassay recovery of cytokines from human serum and simulated vaginal fluid: a multicenter study.
Fichorova R.N., Richardson-Harman, N., Alfano, M., Belec, L., Carbonneil, C., Chen, S., Cosentino, L., Curtis, K., Dezzutti, C.S., Donoval, B. Doncel, G.F., Donaghay, M., Grivel, J.C., Guzman, E., Hayes, M., Herold, B, Hillier, S., Lackman-Smith, C., Landay, A., Margolis, L., Mayer, K.H., Pasicznyk, J.M., Pallansch-Cokonis, M., Poli, G., Reichelderfer, P., Roberts, P., Rodriguez, I., Saidi, H., Sassi, R.R., Shattock, R., Cummins, J.E. Jr.
Anal Chem. 2008
Serum and Colonic Mucosal Immune Markers in Irritable Bowel Syndrome.
Chang L, Adeyemo M, Karagiannidis I, Videlock EJ, Bowe C, Shih W, Presson AP, Yuan PQ, Cortina G, Gong H, Singh S, Licudine A, Mayer M, Tache Y, Pothoulakis C, Mayer EA.
Am J Gastroenterol. 2012
Fetal-placental inflammation, but not adrenal activation, is associated with extreme preterm delivery.
Trivedi S, Joachim M, McElrath T, Kliman HJ, Allred EN, Fichorova RN, Onderdonk A, Heitor F, Chaychi L, Leviton A, Majzoub JA; ELGAN study investigators.
Am J Obstet Gynecol. 2011
Profiling of sputum inflammatory mediators in asthma and chronic obstructive pulmonary disease.
Bafadhel M, McCormick M, Saha S, McKenna S, Shelley M, Hargadon B, Mistry V, Reid C, Parker D, Dodson P, Jenkins M, Lloyd A, Rugman P, Newbold P, Brightling CE.
Respiration. 2012
Effects of Sorafenib on Intra-Tumoral Interstitial Fluid Pressure and Circulating Biomarkers in Patients with Refractory Sarcomas (NCI Protocol 6948).
Raut CP, Boucher Y, Duda DG, Morgan JA, Quek R, Ancukiewicz M, Lahdenranta J, Eder JP, Demetri GD, Jain RK.
PLoS One. 2012
A profile of immune response to herpesvirus is associated with radiographic joint damage in rheumatoid arthritis.
Davis JM 3rd, Knutson KL, Skinner JA, Strausbauch MA, Crowson CS, Therneau TM, Wettstein PJ, Matteson EL, Gabriel SE.
Arthritis Res Ther. 2012
Differential Intestinal M Cell Gene Expression Response to Gut Commensals.
Lapthorne S, Sharry JM, Scully P, Nally K, Shanahan F.
Immunology. 2012
Cycling to work in London and inhaled dose of black carbon.
Nwokoro C, Ewin C, Harrison C, Ibrahim M, Dundas I, Dickson I, Mushtaq N, Grigg J.
Eur Respir J. 2012
Langerhans cells from human cutaneous squamous cell carcinoma induce strong type 1 immunity.
Fujita H, Suárez-Fariñas M, Mitsui H, Gonzalez J, Bluth MJ, Zhang S, Felsen D, Krueger JG, Carucci JA.
J Invest Dermatol. 2012
Macrophages are related to goblet cell hyperplasia and induce MUC5B but not MUC5AC in human bronchus epithelial cells.
Silva MA, Bercik P.
Lab Invest. 2012
Clinical and biomarker profile of trauma-induced secondary cardiac injury.
De'Ath HD, Rourke C, Davenport R, Manson J, Renfrew I, Uppal R, Davies LC, Brohi K.
Br J Surg. 2012
Examining the positive effects of exercise in intubated adults in ICU: A prospective repeated measures clinical study.
Winkelman C, Johnson KD, Hejal R, Gordon NH, Rowbottom J, Daly J, Peereboom K, Levine AD.
Intensive Crit Care Nurs. 2012
A CD4 T cell gene signature for early rheumatoid arthritis implicates interleukin 6-mediated STAT3 signalling, particularly in anti-citrullinated peptide antibody-negative disease.
Pratt AG, Swan DC, Richardson S, Wilson G, Hilkens CM, Young DA, Isaacs JD.
Ann Rheum Dis. 2012
Performance of a multi-biomarker score measuring rheumatoid arthritis disease activity in the CAMERA tight control study.
Bakker MF, Cavet G, Jacobs JW, Bijlsma JW, Haney DJ, Shen Y, Hesterberg LK, Smith DR, Centola M, van Roon JA, Lafeber FP, Welsing PM.
Ann Rheum Dis. 2012
Bananas as an Energy Source during Exercise: A Metabolomics Approach.
Nieman, DC, Gillitt, ND, Henson, DA, Sha, W, Shanely, RA, Knab, AM, Cialdella-Kam, L, Jin, F.
PLoS One. 2012
Human mesenchymal stem cells protect human islets from pro-inflammatory cytokines.
Yeung TY, Seeberger KL, Kin T, Adesida A, Jomha N, Shapiro AM, Korbutt GS.
PLoS One 2012
Phase I Study of Cetuximab, Irinotecan, and Vandetanib (ZD6474) as Therapy for Patients with Previously Treated Metastastic Colorectal Cancer.
Meyerhardt JA, Ancukiewicz M, Abrams TA, Schrag D, Enzinger PC, Chan JA, Kulke MH, Wolpin BM, Goldstein M, Blaszkowsky L, Zhu AX, Elliott M, Regan E, Jain RK, Duda DG.
PLoS One. 2012
Plasma neopterin level as a marker of peripheral immune activation in amnestic mild cognitive impairment and Alzheimer's disease.
Parker DC, Mielke MM, Yu Q, Rosenberg PB, Jain A, Lyketsos CG, Fedarko NS, Oh ES.
Int J Geriatr Psychiatry. 2012
LPS challenge in healthy subjects: An investigation of neutrophil chemotaxis mechanisms involving CXCR1 and CXCR2.
Aul R, Patel S, Summerhill S, Kilty I, Plumb J, Singh D.
Int Immunopharmacol. 2012
Efficiency of log wood combustion affects the toxicological and chemical properties of emission particles.
Tapanainen M, Jalava PI, Mäki-Paakkanen J, Hakulinen P, Lamberg H, Ruusunen J, Tissari J, Jokiniemi J, Hirvonen MR.
Inhal Toxicol. 2012
Depressive symptoms enhance stress-induced inflammatory responses.
Fagundes CP, Glaser R, Hwang BS, Malarkey WB, Kiecolt-Glaser JK.
Brain Behav Immun. 2012
Omega-3 supplementation lowers inflammation in healthy middle-aged and older adults: A randomized controlled trial.
Kiecolt-Glaser JK, Belury MA, Andridge R, Malarkey WB, Hwang BS, Glaser R.
Brain Behav Immun. 2012
Characterization of a multiplex, 12-biomarker test for rheumatoid arthritis.
Eastman PS, Manning WC, Qureshi F, Haney D, Cavet G, Alexander C, Hesterberg LK.
J Pharm Biomed Anal. 2012
Validation of a novel multi-biomarker test to assess rheumatoid arthritis disease activity.
Curtis JR, van der Helm-van Mil AH, Knevel R, Huizinga TW, Haney DJ, Shen Y, Ramanujan S, Cavet G, Centola M, Hesterberg LK, Chernoff D, Ford K, Shadick NA, Hamburger M, Fleischmann R, Keystone E, Weinblatt ME.
Arthritis Care Res. 2012
Blood protein concentrations in the first two postnatal weeks that predict bronchopulmonary dysplasia among infants born before the 28th week of gestation.
Bose, C., Laughon, M., Allred, E.N., Van Marter, L.J., O'shea, T.M., Ehrenkranz, R.A., Fichorova, R., Leviton, A; for the ELGAN Study Investigators.
Pediatr Res. 2011
Synthetic double-stranded RNA induces innate immune responses similar to a live viral vaccine in humans.
Caskey M, Lefebvre F, Filali-Mouhim A, Cameron MJ, Goulet JP, Haddad EK, Breton G, Trumpfheller C, Pollak S, Shimeliovich I, Duque-Alarcon A, Pan L, Nelkenbaum A, Salazar AM, Schlesinger SJ, Steinman RM, Sékaly RP.
J Exp Med. 2011
Phase II Study of Bevacizumab in Patients With HIV-Associated Kaposi's Sarcoma Receiving Antiretroviral Therapy.
Uldrick TS, Wyvill KM, Kumar P, O'Mahony D, Bernstein W, Aleman K, Polizzotto MN, Steinberg SM, Pittaluga S, Marshall V, Whitby D, Little RF, Yarchoan R.
J Clin Oncol. 2012
Ways of coping and biomarkers of an increased atherothrombotic cardiovascular disease risk in elderly individuals.
von Kanel R, Mausbach BT, Dimsdale JE, Mills PJ, Patterson TL, Ancoli-Israel S, Ziegler MG, Roepke SK, Allison M, Grant I.
Cardiovascular Psychiatry and Neurology 2012
Comparison of Multiplex Immunoassay Platforms.
Fu, Q., Zhu, J., Van Eyk, J.E.
Clinical Chemistry. 2010
A CD4 T cell gene signature for early rheumatoid arthritis implicates interleukin 6-mediated STAT3 signalling, particularly in anti-citrullinated peptide antibody-negative disease.
Pratt AG, Swan DC, Richardson S, Wilson G, Hilkens CMU, Young DA, Isaacs JD.
Ann Rheum Dis. 2012
Therapeutic Inhibition of Pro-Inflammatory Signaling and Toxicity to Staphylococcal Enterotoxin B by a Synthetic Dimeric BB-Loop Mimetic of MyD88.
Kissner TL, Ruthel G, Alam S, Mann E, Ajami D, Rebek M, Larkin E, Fernandez S, Ulrich RG, Ping S, Waugh DS, Rebek J Jr, Saikh KU.
PLoS One. 2012
A key role for the endothelium in NOD1 mediated vascular inflammation: comparison to TLR4 responses.
Gatheral T, Reed DM, Moreno L, Gough PJ, Votta BJ, Sehon CA, Rickard DJ, Bertin J, Lim E, Nicholson AG, Mitchell JA.
PLoS One. 2012
Arachidonate 15-Lipoxygenase Type B Knockdown Leads to Reduced Lipid Accumulation and Inflammation in Atherosclerosis.
Magnusson, LU, Lundqvist A, Karlsson MN, Skalen K, Levin M, Wiklund O, Boren J, Hulten LM.
PLoS One 2012
Helicobacter pylori induces in vivo expansion of human regulatory T cells through stimulating IL-1β-production by dendritic cells
Mitchell PJ, Afzali B, Fazekasova H, Chen D, Ali N, Powell N, Lord GM, Lechler RI, Lombardi G.
Clinical & Experimental Immunology 2012
In vitro and clinical studies examining the expression of osteopontin in cigarette smoke-exposed endothelial cells and cigarette smokers.
Bishop E, Theophilus EH, Fearon IM.
BMC Cardiovascular Disorders 2012
Short-term effects of air temperature on blood markers of coagulation and inflammation in potentially susceptible individuals.
Schauble CL, Hampel R, Breitner S, Rückerl R, Phipps R, Diaz-Sanchez D, Devlin RB, Carter JD, Soukup J, Silbajoris R, Dailey L, Koenig W, Cyrys J, Geruschkat U, Belcredi P, Kraus U, Peters A, Schneider AE.
Occup Environ Med. 2012
Chia seed supplementation and disease risk factors in overweight women: a metabolomics investigation.
Nieman DC, Gillitt N, Jin F, Henson DA, Kennerly K, Shanely RA, Ore B, Su M, Schwartz S.
J Altern Complement Med. 2012
Interrelationship of depression, stress and inflammation in cancer patients: A preliminary study.
Archer JA, Hutchison IL, Dorudi S, Stansfeld SA, Korszun A.
J Affect Disord. 2012
Phase I clinical trial of mixed bacterial vaccine (Coley's toxins) in patients with NY-ESO-1 expressing cancers: Immunological effects and clinical activity.
Karbach J, Neumann A, Brand K, Wahle C, Siegel E, Maeurer M, Ritter E, Tsuji T, Gnjatic S, Old LJ, Ritter G, Jäger E.
Clin Cancer Res. 2012
Cartilage and bone markers and inflammatory cytokines are increased in synovial fluid in the acute phase of knee injury (hemarthrosis) - a cross-sectional analysis.
Sward P, Frobell R, Englund M, Roos H, Struglics A.
Osteoarthritis Cartilage. 2012
Changes in novel biomarkers of disease activity in juvenile and adult dermatomyositis are sensitive biomarkers of disease course.
Reed AM, Peterson E, Bilgic H, Ytterberg SR, Amin S, Hein MS, Crowson CS, Ernste F, Gillespie EB.
Arthritis Rheum. 2012
Epstein-Barr virus reactivation during pregnancy and postpartum: Effects of race and racial discrimination.
Christian LM, Iams JD, Porter K, Glaser R.
Brain Behav Immun. 2012
Human parainfluenza virus serotypes differ in their kinetics of replication and cytokine secretion in human tracheobronchial airway epithelium.
Schaap-Nutt A, Liesman R, Bartlett EJ, Scull MA, Collins PL, Pickles RJ, Schmidt AC.
Virology. 2012
Systemic inflammation associated with severe intestinal injury in extremely low gestational age newborns.
Martin CR, Bellomy M, Allred EN, Fichorova RN, Leviton A.
Fetal Pediatr Pathol. 2012
Influenza enhances caspase-1 in bronchial epithelial cells from asthmatic volunteers and is associated with pathogenesis.
Bauer RN, Brighton LE, Mueller L, Xiang Z, Rager JE, Fry RC, Peden DB, Jaspers I.
J Allergy Clin Immunol. 2012
Zip14 expression induced by lipopolysaccharides in macrophages attenuates inflammatory response.
Sayadi A, Nguyen AT, Bard FA, Bard-Chapeau EA.
Inflamm Res. 2012
Endobiont viruses sensed by the human host – Beyond conventional antiparasitic therapy.
Fichorova RN, Lee Y, Yamamoto HS, Takagi Y, Hayes GR, Goodman RP, Chepa-Lotrea X, Buck OR, Murray R, Kula T, Beach DH, Singh BN, Nibert ML.
PLoS One 2012
Influence of red pepper spice and turmeric on inflammation and oxidative stress biomarkers in overweight females: A metabolomics approach.
Nieman DC, Cialdella-Kam L, Knab AM, Shanely RA.
Plant Foods Hum Nutr. 2012
Modest elevation in BNP in asymptomatic hypertensive patients reflects sub-clinical cardiac remodeling, inflammation and extracellular matrix changes.
Phelan D, Watson C, Martos R, Collier P, Patle A, Donnelly S, Ledwidge M, Baugh J, McDonald K.
PLoS One. 2012
Monocytes and γδ T cells control the acute phase response to intravenous zoledronate: Insights from a phase IV safety trial.
Welton JL, Morgan MP, Martí S, Stone MD, Moser B, Sewell AK, Turton J, Eberl M.
J Bone Miner Res. 2012
Workplace based mindfulness practice and inflammation: A randomized trial.
Malarkey WB, Jarjoura D, Klatt M.
Brain Behav Immun. 2012
Systemic inflammation, intraventricular hemorrhage, and white matter injury.
Leviton A, Allred EN, Dammann O, Engelke S, Fichorova RN, Hirtz D, Kuban KC, Ment LR, O'shea TM, Paneth N, Shah B, Schreiber MD.
J Child Neurol. 2012
Selective antagonist reveals the role of prostaglandin receptor EP2 in cancer cell proliferation, invasion and inflammation.
Jiang J, Dingledine R.
J Pharmacol Exp Ther. 2012
Use of PD biomarkers to drive dose selection and early clinical decision making.
Robas NM.
Bioanalysis 2012
Cognitive functions in middle aged individuals are related to metabolic disturbances and aerobic capacity: a cross-sectional study
Pedersen M, Pedersen KK, Bruunsgaard H, Krabbe KS, Thomsen C, Færch K, Pedersen BK, Mortensen EL.
PLoS One. 2012
Interleukin-6 Receptor Polymorphism Is Prevalent in HIV-negative Castleman Disease and Is Associated with Increased Soluble Interleukin-6 Receptor Levels.
Stone K, Woods E, Szmania SM, Stephens OW, Garg TK, Barlogie B, Shaughnessy Jr JD, Hall B, Reddy M, Hoering A, Hansen E, van Rhee F.
PLoS One 2013
Experimental pain and opioid analgesia in volunteers at high risk for obstructive sleep apnea
Doufas AG, Tian L, Padrez KA, Suwanprathes P, Cardell JA, Maecker HT, Panousis P.
PLoS One 2013
Elevated remnant lipoproteins may increase subclinical CVD risk in pre-pubertal children with obesity: a case-control study.
Wang Y, Pendlebury C, Dodd MM, Maximova K, Vine DF, Jetha MM, Ball GD, Proctor SD.
Pediatr Obes. 2012
Correlation between cytokine levels and changes in fatigue and quality of life in patients with acute myeloid leukemia.
Fung FY, Li M, Breunis H, Timilshina N, Minden MD, Alibhai SM.
Leuk Res. 2013
Blood CD33(+)HLA-DR(-) myeloid-derived suppressor cells are increased with age and a history of cancer.
Verschoor CP, Johnstone J, Millar J, Dorrington MG, Habibagahi M, Lelic A, Loeb M, Bramson JL, Bowdish DM.
J Leukoc Biol 2013
Association of IL-12p70 and IL-6:IL-10 ratio with autism-related behaviors in 22q11.2 deletion syndrome: A preliminary report.
Ross H, Guo Y, Coleman K, Ousley O, Miller A.
Brain Behav Immun 2013
TRIF-mediated TLR3 and TLR4 signaling is negatively regulated by ADAM15.
Ahmed S, Maratha A, Butt AQ, Shevlin E, Miggin SM.
J Immunol 2013
A multi-biomarker score measures rheumatoid arthritis disease activity in the BeSt study.
Hirata S, Dirven L, Shen Y, Centola M, Cavet G, Lems WF, Tanaka Y, Huizinga TW, Allaart CF.
Rheumatology (Oxford) 2013
Critical role for apoptosis signal-regulating kinase 1 in the development of inflammatory K/BxN serum-induced arthritis.
Mnich, S.J., Blanner, P.M., Hu, G., Shaffer, A.F., Happa, F.A., O'Neil, S., Ukairo, O., Weiss, D., Welsh, E., Storer, C., Mbalaviele, G., Ichijo, H., Monahan, J.B., Hardy, M.M., Eda, H.
Int Immunopharmacol. 2010
Helicobacter pylori-induced disruption of monolayer permeability and proinflammatory cytokine secretion in polarized human gastric epithelial cells.
Fiorentino M, Ding H, Blanchard TG, Czinn SJ, Sztein MB, Fasano A.
Infect Immun 2013
Biomarkers of inflammation and coagulation are associated with mortality and Hepatitis flares in persons coinfected with HIV and Hepatitis viruses.
Andrade BB, Hullsiek KH, Boulware DR, Rupert A, French MA, Ruxrungtham K, Montes ML, Price H, Barreiro P, Audsley J, Sher A, Lewin SR, Sereti I; for the INSIGHT Study Group.
J Infect Dis 2013
Anti-inflammatory cytokines, pro-fibrogenic chemokines and persistence of acute HCV infection.
Osburn WO, Levine JS, Chattergoon MA, Thomas DL, Cox AL.
Journal of Viral Hepatitis 2013
Phase II study of a neutrophil elastase inhibitor (AZD9668) in patients with bronchiectasis.
Stockley R, De Soyza A, Gunawardena K, Perrett J, Forsman-Semb K, Entwistle N, Snell N.
Respir Med 2013
Associations of interleukin-6 with vegetative but not affective depressive symptoms in terminally ill cancer patients.
Inagaki M, Akechi T, Okuyama T, Sugawara Y, Kinoshita H, Shima Y, Terao K, Mitsunaga S, Ochiai A, Uchitomi Y.
Support Care Cancer 2013
Vital exhaustion and markers of low-grade inflammation in healthy adults: The Amsterdam Growth and Health Longitudinal Study.
Hoekstra T, Barbosa-Leiker C, Twisk JW.
Stress Health 2013
The TARC/sICAM5 ratio in patient plasma is a candidate biomarker for drug resistant epilepsy
Pollard JR, Eidelman O, Mueller GP, Dalgard CL, Crino PB, Anderson CT, Brand EJ, Burakgazi E, Ivaturi SK, Pollard HB.
Front Neurol 2012
A randomized trial of fish oil omega-3 fatty acids on arterial health, inflammation, and metabolic syndrome in a young healthy population.
Root M, Collier SR, Zwetsloot KA, West KL, McGinn MC.
Nutr J 2013
NEW! Inflammation biomarkers in vaginal fluid and preterm delivery.
Taylor BD, Holzman CB, Fichorova RN, Tian Y, Jones NM, Fu W, Senagore PK.
Hum Reprod 2013
NEW! Loneliness promotes inflammation during acute stress.
Jaremka LM, Fagundes CP, Peng J, Bennett JM, Glaser R, Malarkey WB, Kiecolt-Glaser JK.
Psychol Sci 2013
NEW! Elevated sputum Interleukin-5 and submucosal eosinophilia in obese severe asthmatics.
Desai D, Newby C, Symon FA, Haldar P, Shah S, Gupta S, Bafadhel M, Singapuri A, Siddiqui S, Woods J, Herath A, Anderson IK, Bradding P, Green R, Kulkarni N, Pavord I, Marshall RP, Sousa AR, May RD, Wardlaw AJ, Brightling CE.
Am J Respir Crit Care Med. 2013



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